Matches in SemOpenAlex for { <https://semopenalex.org/work/W2915207412> ?p ?o ?g. }
- W2915207412 endingPage "e0212041" @default.
- W2915207412 startingPage "e0212041" @default.
- W2915207412 abstract "This study aimed to screen DNA aptamers against the signal molecule C4-HSL of the rhl system for the inhibition of biofilm formation of Pseudomonas aeruginosa using an improved systematic evolution of ligand by exponential enrichment (SELEX) method based on a structure-switching fluorescent activating bead. The aptamers against the C4-HSL with a high affinity and specifity were successfully obtained and evaluated in real-time by this method. Results of biofilm inhibition experiments in vitro showed that the biofilm formation of P. aeruginosa was efficiently reduced to about 1/3 by the aptamers compared with that of the groups without the aptamers. Independent secondary structure simulation and computer-aided tertiary structure prediction (3dRNA) showed that the aptamers contained a highly conserved Y-shaped structural unit. Therefore, this study benefits the search for new methods for the detection and treatment of P. aeruginosa biofilm formation." @default.
- W2915207412 created "2019-03-02" @default.
- W2915207412 creator A5001362787 @default.
- W2915207412 creator A5019428987 @default.
- W2915207412 creator A5031801059 @default.
- W2915207412 creator A5043774051 @default.
- W2915207412 creator A5065277510 @default.
- W2915207412 date "2019-02-19" @default.
- W2915207412 modified "2023-10-01" @default.
- W2915207412 title "C4-HSL aptamers for blocking qurom sensing and inhibiting biofilm formation in Pseudomonas aeruginosa and its structure prediction and analysis" @default.
- W2915207412 cites W1521289261 @default.
- W2915207412 cites W1585406682 @default.
- W2915207412 cites W1965973263 @default.
- W2915207412 cites W1971647859 @default.
- W2915207412 cites W1992486208 @default.
- W2915207412 cites W1996148766 @default.
- W2915207412 cites W2007995861 @default.
- W2915207412 cites W2014386748 @default.
- W2915207412 cites W2018035550 @default.
- W2915207412 cites W2022012719 @default.
- W2915207412 cites W2039746015 @default.
- W2915207412 cites W2045859085 @default.
- W2915207412 cites W2046448273 @default.
- W2915207412 cites W2053150979 @default.
- W2915207412 cites W2083717115 @default.
- W2915207412 cites W2090985466 @default.
- W2915207412 cites W2091710634 @default.
- W2915207412 cites W2097478029 @default.
- W2915207412 cites W2115308874 @default.
- W2915207412 cites W2119377644 @default.
- W2915207412 cites W2133279153 @default.
- W2915207412 cites W2137729811 @default.
- W2915207412 cites W2137757371 @default.
- W2915207412 cites W2148032806 @default.
- W2915207412 cites W2153842751 @default.
- W2915207412 cites W2163543246 @default.
- W2915207412 cites W2169545551 @default.
- W2915207412 cites W2170291633 @default.
- W2915207412 cites W2325138149 @default.
- W2915207412 cites W2329678482 @default.
- W2915207412 cites W2410223316 @default.
- W2915207412 cites W2463929650 @default.
- W2915207412 cites W2474810755 @default.
- W2915207412 cites W2571964425 @default.
- W2915207412 cites W2594151002 @default.
- W2915207412 cites W4240940294 @default.
- W2915207412 cites W4361805308 @default.
- W2915207412 doi "https://doi.org/10.1371/journal.pone.0212041" @default.
- W2915207412 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6380626" @default.
- W2915207412 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30779754" @default.
- W2915207412 hasPublicationYear "2019" @default.
- W2915207412 type Work @default.
- W2915207412 sameAs 2915207412 @default.
- W2915207412 citedByCount "9" @default.
- W2915207412 countsByYear W29152074122020 @default.
- W2915207412 countsByYear W29152074122021 @default.
- W2915207412 countsByYear W29152074122022 @default.
- W2915207412 countsByYear W29152074122023 @default.
- W2915207412 crossrefType "journal-article" @default.
- W2915207412 hasAuthorship W2915207412A5001362787 @default.
- W2915207412 hasAuthorship W2915207412A5019428987 @default.
- W2915207412 hasAuthorship W2915207412A5031801059 @default.
- W2915207412 hasAuthorship W2915207412A5043774051 @default.
- W2915207412 hasAuthorship W2915207412A5065277510 @default.
- W2915207412 hasBestOaLocation W29152074121 @default.
- W2915207412 hasConcept C104317684 @default.
- W2915207412 hasConcept C122682173 @default.
- W2915207412 hasConcept C12554922 @default.
- W2915207412 hasConcept C128972844 @default.
- W2915207412 hasConcept C153911025 @default.
- W2915207412 hasConcept C185592680 @default.
- W2915207412 hasConcept C2777637488 @default.
- W2915207412 hasConcept C523546767 @default.
- W2915207412 hasConcept C54355233 @default.
- W2915207412 hasConcept C55493867 @default.
- W2915207412 hasConcept C58123911 @default.
- W2915207412 hasConcept C67705224 @default.
- W2915207412 hasConcept C70721500 @default.
- W2915207412 hasConcept C86803240 @default.
- W2915207412 hasConcept C89423630 @default.
- W2915207412 hasConceptScore W2915207412C104317684 @default.
- W2915207412 hasConceptScore W2915207412C122682173 @default.
- W2915207412 hasConceptScore W2915207412C12554922 @default.
- W2915207412 hasConceptScore W2915207412C128972844 @default.
- W2915207412 hasConceptScore W2915207412C153911025 @default.
- W2915207412 hasConceptScore W2915207412C185592680 @default.
- W2915207412 hasConceptScore W2915207412C2777637488 @default.
- W2915207412 hasConceptScore W2915207412C523546767 @default.
- W2915207412 hasConceptScore W2915207412C54355233 @default.
- W2915207412 hasConceptScore W2915207412C55493867 @default.
- W2915207412 hasConceptScore W2915207412C58123911 @default.
- W2915207412 hasConceptScore W2915207412C67705224 @default.
- W2915207412 hasConceptScore W2915207412C70721500 @default.
- W2915207412 hasConceptScore W2915207412C86803240 @default.
- W2915207412 hasConceptScore W2915207412C89423630 @default.
- W2915207412 hasFunder F4320321001 @default.
- W2915207412 hasFunder F4320323190 @default.
- W2915207412 hasIssue "2" @default.