Matches in SemOpenAlex for { <https://semopenalex.org/work/W2915262021> ?p ?o ?g. }
- W2915262021 endingPage "146" @default.
- W2915262021 startingPage "124" @default.
- W2915262021 abstract "BACKGROUNDNovel strategies are needed for improving guided bone regeneration (GBR) in oral surgery prior to implant placement, particularly in maxillary sinus augmentation (GBR-MSA) and in lateral alveolar ridge augmentation (LRA). This study tested the hypothesis that the combination of freshly isolated, unmodified autologous adipose-derived regenerative cells (UA-ADRCs), fraction 2 of plasma rich in growth factors (PRGF-2) and an osteoinductive scaffold (OIS) (UA-ADRC/PRGF-2/OIS) is superior to the combination of PRGF-2 and the same OIS alone (PRGF-2/OIS) in GBR-MSA/LRA. CASE SUMMARYA 79-year-old patient was treated with a bilateral external sinus lift procedure as well as a bilateral lateral alveolar ridge augmentation. GBR-MSA/LRA was performed with UA-ADRC/PRGF-2/OIS on the right side, and with PRGF-2/OIS on the left side. Biopsies were collected at 6 wk and 34 wk after GBR-MSA/LRA. At the latter time point implants were placed. Radiographs (32 mo follow-up time) demonstrated excellent bone healing. No radiological or histological signs of inflammation were observed. Detailed histologic, histomorphometric, and immunohistochemical analysis of the biopsies evidenced that UA-ADRC/PRGF-2/OIS resulted in better and faster bone regeneration than PRGF-2/OIS. CONCLUSIONGBR-MSA with UA-ADRCs, PRGF-2, and an OIS shows effectiveness without adverse effects." @default.
- W2915262021 created "2019-03-02" @default.
- W2915262021 creator A5001138713 @default.
- W2915262021 creator A5019190963 @default.
- W2915262021 creator A5070408180 @default.
- W2915262021 creator A5072906409 @default.
- W2915262021 creator A5077726948 @default.
- W2915262021 creator A5085533869 @default.
- W2915262021 date "2019-02-26" @default.
- W2915262021 modified "2023-10-16" @default.
- W2915262021 title "Improved guided bone regeneration by combined application of unmodified, fresh autologous adipose derived regenerative cells and plasma rich in growth factors: A first-in-human case report and literature review" @default.
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