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- W2915278272 abstract "Macular telangiectasia type 2 (MacTel) is a relatively rare disease without established treatments. Although MacTel was previously considered a primarily vascular condition, the thinking on its pathogenesis has shifted to it now being considered principally a neurodegenerative disease. This has resulted in a subsequent change in the approach to treatment toward neuro-protection for the non-proliferative phase of this disease. Carotenoid supplementation has had mixed results. Ciliary neurotrophic factor (CNTF) has demonstrated some promising early results, but further study is necessary to determine its actual effect. Some structural improvements have been seen in the non-proliferative phase with oral acetazolamide but without accompanying functional improvement. Anti-vascular endothelial drugs have been studied and not found to have benefit in the non-proliferative phase of disease but have demonstrated significant structural and functional value in the treatment of secondary neovascularization. There is no level I evidence for the various proposed MacTel treatments, and efforts need to be directed toward conducting multicenter randomized trials to better understand possible treatments for this condition." @default.
- W2915278272 created "2019-03-02" @default.
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- W2915278272 date "2019-02-20" @default.
- W2915278272 modified "2023-10-18" @default.
- W2915278272 title "Management of Idiopathic Macular Telangiectasia Type 2" @default.
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- W2915278272 cites W1977108733 @default.
- W2915278272 cites W1979047354 @default.
- W2915278272 cites W1986479016 @default.
- W2915278272 cites W1989919076 @default.
- W2915278272 cites W1991210467 @default.
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- W2915278272 doi "https://doi.org/10.1007/s40123-019-0170-1" @default.
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