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• W2915662325 abstract "CXCR7 plays an emerging role in several physiological processes. A linear peptide, amantamide (1), was isolated from marine cyanobacteria, and the structure was determined by NMR and mass spectrometry. The total synthesis was achieved by solid-phase method. After screening two biological target libraries, 1 was identified as a selective CXCR7 agonist. The selective activation of CXCR7 by 1 could provide the basis for developing CXCR7-targeted therapeutics and deciphering the role of CXCR7 in different diseases." @default.
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• W2915662325 date "2019-02-19" @default.
• W2915662325 modified "2023-09-26" @default.
• W2915662325 title "Discovery of Amantamide, a Selective CXCR7 Agonist from Marine Cyanobacteria" @default.
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• W2915662325 doi "https://doi.org/10.1021/acs.orglett.9b00163" @default.
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