Matches in SemOpenAlex for { <https://semopenalex.org/work/W2915685771> ?p ?o ?g. }
- W2915685771 endingPage "1112" @default.
- W2915685771 startingPage "1104" @default.
- W2915685771 abstract "Astroglial networks mediated by gap junction channels contribute to neurotransmission and promote neuronal coordination. Connexin 30, one of the two main astroglial gap junction forming protein, alters at the behavioral level the reactivity of mice to novel environment and at the synaptic level excitatory transmission. However, the role and function of Cx30 at the neuronal network level remain unclear. We thus investigated whether Cx30 regulates neuronal population bursts and associated convulsive behavior. We found in vivo that Cx30 is upregulated by kainate-induced seizures and that it regulates in turn the severity of associated behavioral seizures. Using electrophysiology ex vivo, we report that Cx30 regulates aberrant network activity via control of astroglial glutamate clearance independently of gap-junction mediated biochemical coupling. Altogether, our results indicate that astroglial Cx30 is an important player in orchestrating neuronal network activity." @default.
- W2915685771 created "2019-03-02" @default.
- W2915685771 creator A5000510243 @default.
- W2915685771 creator A5033299269 @default.
- W2915685771 creator A5061966529 @default.
- W2915685771 creator A5091312680 @default.
- W2915685771 date "2019-02-22" @default.
- W2915685771 modified "2023-09-27" @default.
- W2915685771 title "Astroglial Cx30 sustains neuronal population bursts independently of gap‐junction mediated biochemical coupling" @default.
- W2915685771 cites W1547441355 @default.
- W2915685771 cites W1604501714 @default.
- W2915685771 cites W1959780907 @default.
- W2915685771 cites W1966072261 @default.
- W2915685771 cites W1973093449 @default.
- W2915685771 cites W1973112416 @default.
- W2915685771 cites W1974420316 @default.
- W2915685771 cites W1982409010 @default.
- W2915685771 cites W1982952381 @default.
- W2915685771 cites W1984033396 @default.
- W2915685771 cites W1987520241 @default.
- W2915685771 cites W1987710661 @default.
- W2915685771 cites W1995101735 @default.
- W2915685771 cites W1997557640 @default.
- W2915685771 cites W2004115145 @default.
- W2915685771 cites W2008206624 @default.
- W2915685771 cites W2013752437 @default.
- W2915685771 cites W2030663705 @default.
- W2915685771 cites W2035334102 @default.
- W2915685771 cites W2039876485 @default.
- W2915685771 cites W2042681276 @default.
- W2915685771 cites W2048173148 @default.
- W2915685771 cites W2048916015 @default.
- W2915685771 cites W2051046645 @default.
- W2915685771 cites W2066781189 @default.
- W2915685771 cites W2067570041 @default.
- W2915685771 cites W2067988047 @default.
- W2915685771 cites W2075218913 @default.
- W2915685771 cites W2075252509 @default.
- W2915685771 cites W2081608043 @default.
- W2915685771 cites W2083204774 @default.
- W2915685771 cites W2083217982 @default.
- W2915685771 cites W2086457513 @default.
- W2915685771 cites W2104988801 @default.
- W2915685771 cites W2110615319 @default.
- W2915685771 cites W2119774379 @default.
- W2915685771 cites W2127097320 @default.
- W2915685771 cites W2128650885 @default.
- W2915685771 cites W2132112338 @default.
- W2915685771 cites W2136091390 @default.
- W2915685771 cites W2138670140 @default.
- W2915685771 cites W2142358760 @default.
- W2915685771 cites W2147372806 @default.
- W2915685771 cites W2156054910 @default.
- W2915685771 cites W2157414926 @default.
- W2915685771 cites W2158211937 @default.
- W2915685771 cites W2159029858 @default.
- W2915685771 cites W2160464539 @default.
- W2915685771 cites W2160644313 @default.
- W2915685771 cites W2165986036 @default.
- W2915685771 cites W2171891895 @default.
- W2915685771 cites W2178878227 @default.
- W2915685771 cites W2237168544 @default.
- W2915685771 cites W2744137535 @default.
- W2915685771 cites W2752703006 @default.
- W2915685771 cites W2763529605 @default.
- W2915685771 cites W2771558655 @default.
- W2915685771 doi "https://doi.org/10.1002/glia.23591" @default.
- W2915685771 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6519011" @default.
- W2915685771 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30794327" @default.
- W2915685771 hasPublicationYear "2019" @default.
- W2915685771 type Work @default.
- W2915685771 sameAs 2915685771 @default.
- W2915685771 citedByCount "11" @default.
- W2915685771 countsByYear W29156857712019 @default.
- W2915685771 countsByYear W29156857712020 @default.
- W2915685771 countsByYear W29156857712021 @default.
- W2915685771 countsByYear W29156857712023 @default.
- W2915685771 crossrefType "journal-article" @default.
- W2915685771 hasAuthorship W2915685771A5000510243 @default.
- W2915685771 hasAuthorship W2915685771A5033299269 @default.
- W2915685771 hasAuthorship W2915685771A5061966529 @default.
- W2915685771 hasAuthorship W2915685771A5091312680 @default.
- W2915685771 hasBestOaLocation W29156857711 @default.
- W2915685771 hasConcept C112592302 @default.
- W2915685771 hasConcept C158157758 @default.
- W2915685771 hasConcept C160268369 @default.
- W2915685771 hasConcept C169760540 @default.
- W2915685771 hasConcept C170493617 @default.
- W2915685771 hasConcept C17077164 @default.
- W2915685771 hasConcept C189184402 @default.
- W2915685771 hasConcept C200170125 @default.
- W2915685771 hasConcept C2777542381 @default.
- W2915685771 hasConcept C2780228694 @default.
- W2915685771 hasConcept C2908647359 @default.
- W2915685771 hasConcept C529278444 @default.
- W2915685771 hasConcept C55493867 @default.
- W2915685771 hasConcept C61174792 @default.
- W2915685771 hasConcept C71924100 @default.