Matches in SemOpenAlex for { <https://semopenalex.org/work/W2915698323> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W2915698323 endingPage "1925" @default.
- W2915698323 startingPage "1921" @default.
- W2915698323 abstract "Purpose The purpose of this study was to develop a pre-operative risk assessment tool for childhood and adolescent ovarian malignancy, in order to guide operative management of pediatric ovarian masses. Methods We conducted a retrospective analysis of patients <18 years old who underwent ovarian surgery at two quaternary care pediatric centers over 4 years (1/1/13–12/31/16). Probability of malignancy was estimated based on imaging characteristics (simple cyst, heterogeneous, or solid), maximal diameter, and tumor markers (α-fetoprotein, β-human chorionic gonadotropin). Results Among 188 children with ovarian masses, 11% had malignancies. For simple cysts, there were no malignancies (0/24, 95% CI = 0–17%). Among solid lesions, 44% (15/34, 95% CI = 28–62%) were malignant. Among marker-elevated heterogeneous masses, 40% (2/5, 95% CI = 12–77%) were malignant. Conversely, small (≤10 cm) and large (>10 cm) marker-negative heterogeneous lesions had malignancy proportions of 0% (0/39, 95% CI = 0–11%) and 5% (2/40, 95% CI = 1–18%), respectively. Conclusions Given the malignancy estimates identified from these multi-institutional data, we recommend an attempt at ovarian-sparing resection for simple cysts or tumor marker-negative heterogeneous lesions ≤10 cm. Oophorectomy is recommended for solid masses or heterogeneous lesions with elevated markers. Finally, large (>10 cm) heterogeneous masses with non-elevated markers warrant a careful discussion of ovarian-sparing techniques. Complete surgical staging is mandatory regardless of operative procedure. Type of Study Study of Diagnostic Test. Level of Evidence Level I." @default.
- W2915698323 created "2019-03-02" @default.
- W2915698323 creator A5000265695 @default.
- W2915698323 creator A5010260826 @default.
- W2915698323 creator A5012637798 @default.
- W2915698323 creator A5018600971 @default.
- W2915698323 creator A5019568309 @default.
- W2915698323 creator A5020672409 @default.
- W2915698323 creator A5032126905 @default.
- W2915698323 creator A5037740620 @default.
- W2915698323 creator A5055771015 @default.
- W2915698323 creator A5072248130 @default.
- W2915698323 creator A5078106172 @default.
- W2915698323 date "2019-09-01" @default.
- W2915698323 modified "2023-10-16" @default.
- W2915698323 title "Multicenter pre-operative assessment of pediatric ovarian malignancy" @default.
- W2915698323 cites W1965772308 @default.
- W2915698323 cites W1967550853 @default.
- W2915698323 cites W1997517877 @default.
- W2915698323 cites W2028236696 @default.
- W2915698323 cites W2101983821 @default.
- W2915698323 cites W2108484617 @default.
- W2915698323 cites W2110976869 @default.
- W2915698323 cites W2117352205 @default.
- W2915698323 cites W2119691301 @default.
- W2915698323 cites W2123668071 @default.
- W2915698323 cites W2128942908 @default.
- W2915698323 cites W2141405866 @default.
- W2915698323 cites W2146272590 @default.
- W2915698323 cites W2312938254 @default.
- W2915698323 cites W2409123357 @default.
- W2915698323 cites W2596094167 @default.
- W2915698323 cites W2740976433 @default.
- W2915698323 cites W4238595708 @default.
- W2915698323 doi "https://doi.org/10.1016/j.jpedsurg.2019.02.019" @default.
- W2915698323 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30867096" @default.
- W2915698323 hasPublicationYear "2019" @default.
- W2915698323 type Work @default.
- W2915698323 sameAs 2915698323 @default.
- W2915698323 citedByCount "14" @default.
- W2915698323 countsByYear W29156983232019 @default.
- W2915698323 countsByYear W29156983232020 @default.
- W2915698323 countsByYear W29156983232021 @default.
- W2915698323 countsByYear W29156983232022 @default.
- W2915698323 countsByYear W29156983232023 @default.
- W2915698323 crossrefType "journal-article" @default.
- W2915698323 hasAuthorship W2915698323A5000265695 @default.
- W2915698323 hasAuthorship W2915698323A5010260826 @default.
- W2915698323 hasAuthorship W2915698323A5012637798 @default.
- W2915698323 hasAuthorship W2915698323A5018600971 @default.
- W2915698323 hasAuthorship W2915698323A5019568309 @default.
- W2915698323 hasAuthorship W2915698323A5020672409 @default.
- W2915698323 hasAuthorship W2915698323A5032126905 @default.
- W2915698323 hasAuthorship W2915698323A5037740620 @default.
- W2915698323 hasAuthorship W2915698323A5055771015 @default.
- W2915698323 hasAuthorship W2915698323A5072248130 @default.
- W2915698323 hasAuthorship W2915698323A5078106172 @default.
- W2915698323 hasConcept C121608353 @default.
- W2915698323 hasConcept C126322002 @default.
- W2915698323 hasConcept C126838900 @default.
- W2915698323 hasConcept C143998085 @default.
- W2915698323 hasConcept C2779399171 @default.
- W2915698323 hasConcept C2780302416 @default.
- W2915698323 hasConcept C2780427987 @default.
- W2915698323 hasConcept C2780597408 @default.
- W2915698323 hasConcept C2781447364 @default.
- W2915698323 hasConcept C71924100 @default.
- W2915698323 hasConceptScore W2915698323C121608353 @default.
- W2915698323 hasConceptScore W2915698323C126322002 @default.
- W2915698323 hasConceptScore W2915698323C126838900 @default.
- W2915698323 hasConceptScore W2915698323C143998085 @default.
- W2915698323 hasConceptScore W2915698323C2779399171 @default.
- W2915698323 hasConceptScore W2915698323C2780302416 @default.
- W2915698323 hasConceptScore W2915698323C2780427987 @default.
- W2915698323 hasConceptScore W2915698323C2780597408 @default.
- W2915698323 hasConceptScore W2915698323C2781447364 @default.
- W2915698323 hasConceptScore W2915698323C71924100 @default.
- W2915698323 hasIssue "9" @default.
- W2915698323 hasLocation W29156983231 @default.
- W2915698323 hasLocation W29156983232 @default.
- W2915698323 hasOpenAccess W2915698323 @default.
- W2915698323 hasPrimaryLocation W29156983231 @default.
- W2915698323 hasRelatedWork W130409979 @default.
- W2915698323 hasRelatedWork W2024987942 @default.
- W2915698323 hasRelatedWork W2145231085 @default.
- W2915698323 hasRelatedWork W2365608035 @default.
- W2915698323 hasRelatedWork W2411595064 @default.
- W2915698323 hasRelatedWork W2411782998 @default.
- W2915698323 hasRelatedWork W3045649719 @default.
- W2915698323 hasRelatedWork W4293224485 @default.
- W2915698323 hasRelatedWork W4295226747 @default.
- W2915698323 hasRelatedWork W2948697744 @default.
- W2915698323 hasVolume "54" @default.
- W2915698323 isParatext "false" @default.
- W2915698323 isRetracted "false" @default.
- W2915698323 magId "2915698323" @default.
- W2915698323 workType "article" @default.