Matches in SemOpenAlex for { <https://semopenalex.org/work/W2915961477> ?p ?o ?g. }
- W2915961477 endingPage "76" @default.
- W2915961477 startingPage "67" @default.
- W2915961477 abstract "(1) To develop a novel bioactive root canal sealer with antibiofilm and remineralization properties using dimethylaminohexadecyl methacrylate (DMAHDM) and nanoparticles of amorphous calcium phosphate (NACP); (2) investigate the effects on E. faecalis biofilm inhibition, sealer flow and sealing ability, compared with an epoxy-resin-based sealer AH Plus; and (3) investigate the calcium (Ca) and phosphate (P) ion release from the sealers.A series of dual-cure endodontic sealers were formulated with DMAHDM and NACP at 5% and 20% by mass, respectively. Flow properties and sealing ability of the sealers were measured. Colony-forming units (CFU), live/dead assay, and polysaccharide production of biofilms on sealers were determined. Ca and P ion releases from the sealers were measured.The new sealer containing 20% NACP and 5% DMAHDM yielded a paste flow of (28.99 ± 0.69) mm, within the range of ISO recommendations. The sealing properties of the sealer with 5% DMAHDM and 20% NACP were similar to a commercial control (p > 0.05). The sealer with DMAHDM decreased E. faecalis biofilm CFU by more than 4 orders of magnitude, compared to AH plus and experimental controls. The sealer with 20% NACP and 5% DMAHDM had relatively high levels of Ca and P ion release necessary for remineralization.A new bioactive endodontic sealer was developed with strong antibiofilm activity against E. faecalis biofilms and high levels of Ca and P ion release for remineralization, without compromising the paste flow and sealing properties.The bioactive antibacterial and remineralizing root canal sealer is promising to inhibit E. faecalis biofilms to prevent endodontic treatment failure and secondary endodontic infections, while releasing high levels of Ca and P ions that could remineralize and strengthen the tooth structures and potentially prevent future root fractures and teeth extractions." @default.
- W2915961477 created "2019-03-02" @default.
- W2915961477 creator A5006690496 @default.
- W2915961477 creator A5042228098 @default.
- W2915961477 creator A5047718865 @default.
- W2915961477 creator A5053640827 @default.
- W2915961477 creator A5061900770 @default.
- W2915961477 creator A5074872099 @default.
- W2915961477 creator A5081161678 @default.
- W2915961477 creator A5088320537 @default.
- W2915961477 date "2019-04-01" @default.
- W2915961477 modified "2023-10-10" @default.
- W2915961477 title "Novel bioactive root canal sealer with antibiofilm and remineralization properties" @default.
- W2915961477 cites W1539125265 @default.
- W2915961477 cites W1918905072 @default.
- W2915961477 cites W1964975641 @default.
- W2915961477 cites W1967017908 @default.
- W2915961477 cites W1968040337 @default.
- W2915961477 cites W1981133001 @default.
- W2915961477 cites W1981378977 @default.
- W2915961477 cites W1983241034 @default.
- W2915961477 cites W1984819833 @default.
- W2915961477 cites W1987336642 @default.
- W2915961477 cites W2013741962 @default.
- W2915961477 cites W2018388671 @default.
- W2915961477 cites W2024550809 @default.
- W2915961477 cites W2025080495 @default.
- W2915961477 cites W2029989802 @default.
- W2915961477 cites W2042774380 @default.
- W2915961477 cites W2042879923 @default.
- W2915961477 cites W2043662853 @default.
- W2915961477 cites W2043934813 @default.
- W2915961477 cites W2044395861 @default.
- W2915961477 cites W2049959883 @default.
- W2915961477 cites W2053098444 @default.
- W2915961477 cites W2054003035 @default.
- W2915961477 cites W2064005517 @default.
- W2915961477 cites W2071537545 @default.
- W2915961477 cites W2078579619 @default.
- W2915961477 cites W2082723728 @default.
- W2915961477 cites W2087882436 @default.
- W2915961477 cites W2107809819 @default.
- W2915961477 cites W2111302020 @default.
- W2915961477 cites W2114684396 @default.
- W2915961477 cites W2124945708 @default.
- W2915961477 cites W2127723704 @default.
- W2915961477 cites W2132104110 @default.
- W2915961477 cites W2132612531 @default.
- W2915961477 cites W2144049824 @default.
- W2915961477 cites W2144440398 @default.
- W2915961477 cites W2144494270 @default.
- W2915961477 cites W2148784801 @default.
- W2915961477 cites W2152088778 @default.
- W2915961477 cites W2152796130 @default.
- W2915961477 cites W2157532610 @default.
- W2915961477 cites W2159856643 @default.
- W2915961477 cites W2170097513 @default.
- W2915961477 cites W2171375246 @default.
- W2915961477 cites W2276733167 @default.
- W2915961477 cites W2278134576 @default.
- W2915961477 cites W2345871120 @default.
- W2915961477 cites W2519804936 @default.
- W2915961477 cites W2521681161 @default.
- W2915961477 cites W2528569552 @default.
- W2915961477 cites W2549217154 @default.
- W2915961477 cites W2566792252 @default.
- W2915961477 cites W2590557660 @default.
- W2915961477 cites W2603531426 @default.
- W2915961477 cites W2620987087 @default.
- W2915961477 cites W2738458382 @default.
- W2915961477 cites W2759278838 @default.
- W2915961477 cites W2777379641 @default.
- W2915961477 cites W2790097242 @default.
- W2915961477 cites W2794494490 @default.
- W2915961477 cites W2802350694 @default.
- W2915961477 cites W2888868131 @default.
- W2915961477 cites W4234095729 @default.
- W2915961477 doi "https://doi.org/10.1016/j.jdent.2019.02.006" @default.
- W2915961477 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30825569" @default.
- W2915961477 hasPublicationYear "2019" @default.
- W2915961477 type Work @default.
- W2915961477 sameAs 2915961477 @default.
- W2915961477 citedByCount "28" @default.
- W2915961477 countsByYear W29159614772019 @default.
- W2915961477 countsByYear W29159614772020 @default.
- W2915961477 countsByYear W29159614772021 @default.
- W2915961477 countsByYear W29159614772022 @default.
- W2915961477 countsByYear W29159614772023 @default.
- W2915961477 crossrefType "journal-article" @default.
- W2915961477 hasAuthorship W2915961477A5006690496 @default.
- W2915961477 hasAuthorship W2915961477A5042228098 @default.
- W2915961477 hasAuthorship W2915961477A5047718865 @default.
- W2915961477 hasAuthorship W2915961477A5053640827 @default.
- W2915961477 hasAuthorship W2915961477A5061900770 @default.
- W2915961477 hasAuthorship W2915961477A5074872099 @default.
- W2915961477 hasAuthorship W2915961477A5081161678 @default.
- W2915961477 hasAuthorship W2915961477A5088320537 @default.
- W2915961477 hasConcept C104317684 @default.