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• W2916093760 abstract "Abstract This study examines health outcomes in burn patients with sepsis. We hypothesized that burn patients with sepsis would have an increased odds risk for in-hospital death and longer intensive care unit (ICU) stays. This was a retrospective cohort of consecutive patients admitted to the burn ICU with total BSA (TBSA) ≥10% and/or inhalation injury between January 2008 and March 2015. Overall 407 burn patients were included; the case-rate for sepsis was 39.1% (n = 159); 20.1% (n = 82) patients were septic and 18.9% (n = 77) patients experienced septic shock. Patients with septic shock had the highest mortality rate (13.31% no sepsis vs 3.7% sepsis vs 49.4% septic shock, P &lt; .01). Median 28-day ICU-free days was higher in patients without sepsis (23 days [Interquartile range (IQR) 14–27] no sepsis vs 0 days [IQR 0–10] sepsis vs 0 days [IQR 0–0] septic shock, P &lt; .01). Sepsis (with or without shock) increased odds of in-hospital death (odds ratio 7.04, 95% confidence interval 1.93–25.7) in reference to the no sepsis group. With each incremental Sequential Organ Failure Assessment (SOFA) score or 10% TBSA increase, the odds risk for in-hospital death increased by 56 and 75%, respectively. Our study characterized outcomes in patients with sepsis after severe burn injury. The odds risk for in-hospital death was greater in patients with sepsis, increasing burn severity according to TBSA and SOFA score." @default.
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• W2916093760 date "2019-02-26" @default.
• W2916093760 modified "2023-09-24" @default.
• W2916093760 title "Outcomes in Burn-Injured Patients Who Develop Sepsis" @default.
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• W2916093760 doi "https://doi.org/10.1093/jbcr/irz017" @default.
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