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- W2916104780 abstract "Purpose Multifocal/multicentric breast carcinoma (M/MBC) is defined in cases with two or more foci in same and different quadrants of breasts. Digital breast tomosynthesis (DBT) addition to digital mammography (DM) increases the diagnosis of breast lesions and malignancies. While DM, has low sensitivity in multifocal lesion detection, additional ultrasonography (US) increases diagnostic performance. However, magnetic resonance imaging (MRI) has the highest sensitivity in M/MBC determination. We here aimed to investigate diagnostic value of DBT with and without additional US examination in M/MBC. We evaluated our results with MRI comparatively. Material and Methods Between April 2014-March 2017, 64 patients with pre-diagnosis of M/MBC were enrolled study. DBT, US, and MRI were reviewed separately. One breast radiologist carried out the review, retrospectively. MRI findings were accepted as gold standard. Lesions and foci of M/MBC in DBT were classified by presence of calcifications, spiculate masses and asymmetric fibroglandular tissues. Patients’ m ean data were compared by one-way analysis of variance (ANOVA). Interrelated variables were evaluated by using cross tables and Qui Square Tests. P value was accepted as p < 0.05. Results DBT diagnosed 53 breasts in 52 patients as M/MBC. Sensitivity of DBT was 76.1%, specificity was 83.3% (p=0.77). US evaluation revealed that 46 breasts in 45 patients had M/MBC. Sensitivity and specificity of US were 74.1% and 78.8%, respectively (p=0.1). US addition to DBT increased sensitivity to 94,2%. Conclusion MRI detects lesions, lesion spread and the dimensions with high accuracy. It is important that, in M/MBC, US and MRI addition to DBT provides false positivity and negativity decrease, prevents reoperations." @default.
- W2916104780 created "2019-03-02" @default.
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- W2916104780 date "2019-03-01" @default.
- W2916104780 modified "2023-10-18" @default.
- W2916104780 title "Effectiveness of Digital Tomosynthesis in Multifocal/Multicentric Breast Cancer: A Pilot Study" @default.
- W2916104780 doi "https://doi.org/10.16919/bozoktip.450988" @default.
- W2916104780 hasPublicationYear "2019" @default.
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