FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2916166238> ?p ?o ?g. }

• W2916166238 abstract "Measuring concentrations of metabolites of estradiol and progesterone in urine, instead of measuring serum concentrations, is common in research and also is used in patient care. The primary aim of this study was to demonstrate that analysis of urine samples dried on filter paper by gas chromatography with tandem mass spectrometry (GC-MS/MS) provides results similar to serum analyzed by radioimmunoassay (RIA). Secondary aims were to show that collection of four samples during the day (4-spot method) can be substituted for a 24-h collection, and that analysis of urine from dried samples is equivalent to liquid urine samples.This prospective observational study compared results of urine and serum analyses. Urine samples from women throughout the menstrual cycle and single samples from postmenopausal women were evaluated. Urine was collected onto filter paper and dried. Dried urine was extracted, hydrolyzed, and derivatized prior to analysis by GC-MS/MS. Hormone concentrations were normalized to creatinine. Single samples were used to compare results of 24-h urine collection to the 4-spot method from a separate population of women and men. A subset of these samples were used to compare results from dried urine to liquid urine.The primary study showed good reliability in the comparisons between the dried urine and serum assays. During the menstrual cycles of a subset of four women, urine metabolite concentrations followed the same pattern as serum concentrations. Comparison of 4-spot to 24-h urine collections and of dried to liquid urine measurements had intraclass correlation coefficients (ICC) greater than 0.95, indicating excellent agreement.For estradiol and progesterone, the dried urine assay is a good surrogate for serum testing. The 4-spot method can be used instead of 24-h urine collections and dried urine results are comparable to liquid urine. The dried urine assay is useful for some clinical assessments of hormone disorders and may be useful in large epidemiologic studies due to ease of sample handling." @default.
• W2916166238 created "2019-03-02" @default.
• W2916166238 creator A5013855410 @default.
• W2916166238 creator A5033042160 @default.
• W2916166238 creator A5037144037 @default.
• W2916166238 creator A5089494098 @default.
• W2916166238 date "2019-02-04" @default.
• W2916166238 modified "2023-10-08" @default.
• W2916166238 title "Evaluating urinary estrogen and progesterone metabolites using dried filter paper samples and gas chromatography with tandem mass spectrometry (GC–MS/MS)" @default.
• W2916166238 cites W1700762969 @default.
• W2916166238 cites W1985139791 @default.
• W2916166238 cites W1996532697 @default.
• W2916166238 cites W2011956717 @default.
• W2916166238 cites W2083551372 @default.
• W2916166238 cites W2098157949 @default.
• W2916166238 cites W2104090353 @default.
• W2916166238 cites W2105624384 @default.
• W2916166238 cites W2110492067 @default.
• W2916166238 cites W2144319070 @default.
• W2916166238 cites W2149210130 @default.
• W2916166238 cites W2156455308 @default.
• W2916166238 cites W2164777277 @default.
• W2916166238 doi "https://doi.org/10.1186/s13065-019-0539-1" @default.
• W2916166238 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6661742" @default.
• W2916166238 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31384769" @default.
• W2916166238 hasPublicationYear "2019" @default.
• W2916166238 type Work @default.
• W2916166238 sameAs 2916166238 @default.
• W2916166238 citedByCount "22" @default.
• W2916166238 countsByYear W29161662382019 @default.
• W2916166238 countsByYear W29161662382020 @default.
• W2916166238 countsByYear W29161662382021 @default.
• W2916166238 countsByYear W29161662382022 @default.
• W2916166238 countsByYear W29161662382023 @default.
• W2916166238 crossrefType "journal-article" @default.
• W2916166238 hasAuthorship W2916166238A5013855410 @default.
• W2916166238 hasAuthorship W2916166238A5033042160 @default.
• W2916166238 hasAuthorship W2916166238A5037144037 @default.
• W2916166238 hasAuthorship W2916166238A5089494098 @default.
• W2916166238 hasBestOaLocation W29161662381 @default.
• W2916166238 hasConcept C162356407 @default.
• W2916166238 hasConcept C185592680 @default.
• W2916166238 hasConcept C205345274 @default.
• W2916166238 hasConcept C2777477808 @default.
• W2916166238 hasConcept C2780026642 @default.
• W2916166238 hasConcept C43617362 @default.
• W2916166238 hasConcept C55493867 @default.
• W2916166238 hasConceptScore W2916166238C162356407 @default.
• W2916166238 hasConceptScore W2916166238C185592680 @default.
• W2916166238 hasConceptScore W2916166238C205345274 @default.
• W2916166238 hasConceptScore W2916166238C2777477808 @default.
• W2916166238 hasConceptScore W2916166238C2780026642 @default.
• W2916166238 hasConceptScore W2916166238C43617362 @default.
• W2916166238 hasConceptScore W2916166238C55493867 @default.
• W2916166238 hasIssue "1" @default.
• W2916166238 hasLocation W29161662381 @default.
• W2916166238 hasLocation W29161662382 @default.
• W2916166238 hasLocation W29161662383 @default.
• W2916166238 hasLocation W29161662384 @default.
• W2916166238 hasLocation W29161662385 @default.
• W2916166238 hasOpenAccess W2916166238 @default.
• W2916166238 hasPrimaryLocation W29161662381 @default.
• W2916166238 hasRelatedWork W1976626766 @default.
• W2916166238 hasRelatedWork W1984052295 @default.
• W2916166238 hasRelatedWork W1989198756 @default.
• W2916166238 hasRelatedWork W1990694197 @default.
• W2916166238 hasRelatedWork W2003174742 @default.
• W2916166238 hasRelatedWork W2008651038 @default.
• W2916166238 hasRelatedWork W2043524890 @default.
• W2916166238 hasRelatedWork W2067605410 @default.
• W2916166238 hasRelatedWork W2072164925 @default.
• W2916166238 hasRelatedWork W3021100874 @default.
• W2916166238 hasVolume "13" @default.
• W2916166238 isParatext "false" @default.
• W2916166238 isRetracted "false" @default.
• W2916166238 magId "2916166238" @default.
• W2916166238 workType "article" @default.