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- W2916236864 abstract "Advances in stem cell research have made revolutionary changes to healthcare and medicine, holding promise for the restoration and regeneration of dysfunctional cells for a wide range of diseases and injuries. Ophthalmology stands at the forefront of this new technology with cultivated limbal epithelial transplantation (CLET) as a prime example of these cell-based therapies. CLET aims to restore the ocular surface in stem cell-deficient eyes by transplanting ex vivo expanded stem cell grafts. Cells are harvested from a healthy limbus, grown and multiplied in a laboratory for several days and then transplanted onto the stem cell-deficient eye. Since the introduction of this technique in 1997, numerous cultivation methods and surgical approaches have been used in various centres worldwide. In the majority of cases, the technique has been shown to successfully regenerate the corneal epithelium." @default.
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- W2916236864 date "2019-01-01" @default.
- W2916236864 modified "2023-10-14" @default.
- W2916236864 title "Cultivated Limbal Stem Cell Transplantation: Indications and Technique" @default.
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- W2916236864 doi "https://doi.org/10.1007/978-3-030-01304-2_19" @default.
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