Matches in SemOpenAlex for { <https://semopenalex.org/work/W2916506247> ?p ?o ?g. }
- W2916506247 endingPage "13" @default.
- W2916506247 startingPage "1" @default.
- W2916506247 abstract "Endothelial dysfunction is characterized by nitric oxide dysregulation and an altered redox state. Oxidative stress and inflammatory markers prevail, thus promoting atherogenesis and hypertension, important risk factors for the development and progression of heart failure. There has been a reemerging interest in the role that endothelial dysfunction plays in the failing circulation. Accordingly, patients with heart failure are being clinically assessed for endothelial dysfunction via various methods, including flow-mediated vasodilation, peripheral arterial tonometry, quantification of circulating endothelial progenitor cells, and early and late endothelial progenitor cell outgrowth measurements. Although the mechanisms underlying endothelial dysfunction are intimately related to cardiovascular disease and heart failure, it remains unclear whether targeting endothelial dysfunction is a feasible strategy for ameliorating heart failure progression. This review focuses on the pathophysiology of endothelial dysfunction, the mechanisms linking endothelial dysfunction and heart failure, and the various diagnostic methods currently used to measure endothelial function, ultimately highlighting the therapeutic implications of targeting endothelial dysfunction for the treatment of heart failure." @default.
- W2916506247 created "2019-03-02" @default.
- W2916506247 creator A5064682818 @default.
- W2916506247 creator A5079149524 @default.
- W2916506247 creator A5085774808 @default.
- W2916506247 creator A5086268360 @default.
- W2916506247 date "2019-03-01" @default.
- W2916506247 modified "2023-10-16" @default.
- W2916506247 title "Rethinking Endothelial Dysfunction as a Crucial Target in Fighting Heart Failure" @default.
- W2916506247 cites W113644040 @default.
- W2916506247 cites W1503505289 @default.
- W2916506247 cites W1607867060 @default.
- W2916506247 cites W1700072306 @default.
- W2916506247 cites W1715320380 @default.
- W2916506247 cites W1921078192 @default.
- W2916506247 cites W1930421067 @default.
- W2916506247 cites W1969789360 @default.
- W2916506247 cites W1974769258 @default.
- W2916506247 cites W1980445357 @default.
- W2916506247 cites W1983580215 @default.
- W2916506247 cites W1985757967 @default.
- W2916506247 cites W1987529279 @default.
- W2916506247 cites W1991875014 @default.
- W2916506247 cites W1995444906 @default.
- W2916506247 cites W1996873499 @default.
- W2916506247 cites W2000117038 @default.
- W2916506247 cites W2012124023 @default.
- W2916506247 cites W2017499594 @default.
- W2916506247 cites W2024324080 @default.
- W2916506247 cites W2025669009 @default.
- W2916506247 cites W2028063897 @default.
- W2916506247 cites W2028139057 @default.
- W2916506247 cites W2031166312 @default.
- W2916506247 cites W2036987415 @default.
- W2916506247 cites W2040603631 @default.
- W2916506247 cites W2045019896 @default.
- W2916506247 cites W2045402361 @default.
- W2916506247 cites W2046060950 @default.
- W2916506247 cites W2047688401 @default.
- W2916506247 cites W2049978396 @default.
- W2916506247 cites W2052932260 @default.
- W2916506247 cites W2057116025 @default.
- W2916506247 cites W2061566600 @default.
- W2916506247 cites W2061834165 @default.
- W2916506247 cites W2062541458 @default.
- W2916506247 cites W2063506869 @default.
- W2916506247 cites W2067292833 @default.
- W2916506247 cites W2068519950 @default.
- W2916506247 cites W2069367967 @default.
- W2916506247 cites W2072122716 @default.
- W2916506247 cites W2073069044 @default.
- W2916506247 cites W2073179272 @default.
- W2916506247 cites W2074035327 @default.
- W2916506247 cites W2075515334 @default.
- W2916506247 cites W2076269747 @default.
- W2916506247 cites W2083765557 @default.
- W2916506247 cites W2084327878 @default.
- W2916506247 cites W2089195576 @default.
- W2916506247 cites W2096151264 @default.
- W2916506247 cites W2100127875 @default.
- W2916506247 cites W2113617288 @default.
- W2916506247 cites W2122386753 @default.
- W2916506247 cites W2122880159 @default.
- W2916506247 cites W2127254785 @default.
- W2916506247 cites W2127872440 @default.
- W2916506247 cites W2132250523 @default.
- W2916506247 cites W2141665762 @default.
- W2916506247 cites W2147993424 @default.
- W2916506247 cites W2148477337 @default.
- W2916506247 cites W2148637873 @default.
- W2916506247 cites W2152072062 @default.
- W2916506247 cites W2161918376 @default.
- W2916506247 cites W2161982738 @default.
- W2916506247 cites W2165029049 @default.
- W2916506247 cites W2165753570 @default.
- W2916506247 cites W2169354842 @default.
- W2916506247 cites W2170597525 @default.
- W2916506247 cites W2205684329 @default.
- W2916506247 cites W2290762340 @default.
- W2916506247 cites W2292856586 @default.
- W2916506247 cites W2318781926 @default.
- W2916506247 cites W2335161036 @default.
- W2916506247 cites W2427094903 @default.
- W2916506247 cites W2475261460 @default.
- W2916506247 cites W2477345637 @default.
- W2916506247 cites W2517631128 @default.
- W2916506247 cites W2549128727 @default.
- W2916506247 cites W2591267093 @default.
- W2916506247 cites W2594052307 @default.
- W2916506247 cites W2594271032 @default.
- W2916506247 cites W2605862990 @default.
- W2916506247 cites W2609605008 @default.
- W2916506247 cites W2618268791 @default.
- W2916506247 cites W2644819006 @default.
- W2916506247 cites W2744603107 @default.
- W2916506247 cites W2773779644 @default.
- W2916506247 cites W2786059401 @default.
- W2916506247 cites W2790616177 @default.