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- W2916715270 abstract "A phytochemical study on the stem bark of Metasequoia glyptostroboides led to the isolation of sixty-one diterpenoids and sesquiterpenoids, including seventeen previously undescribed compounds, metaglyptins A-Q. Their structures were elucidated by extensive analysis of spectroscopic data (IR, UV, HRESIMS, and 1H, 13C and 2D NMR). The absolute configurations of metaglyptins I, J, and O were determined by the ECD data and single-crystal X-ray diffraction analysis. The undescribed compounds were evaluated for their cytotoxicity against HeLa, AGS, and MDA-MB-231 cancer cell lines. The results revealed that metaglyptin A exhibited moderate cytotoxicity against MDA-MB-231 cell line with IC50 value of 20.02 μM." @default.
- W2916715270 created "2019-03-02" @default.
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- W2916715270 date "2019-05-01" @default.
- W2916715270 modified "2023-09-30" @default.
- W2916715270 title "Diterpenoids and sesquiterpenoids from the stem bark of Metasequoia glyptostroboides" @default.
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- W2916715270 doi "https://doi.org/10.1016/j.phytochem.2019.02.008" @default.
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