FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2916839666> ?p ?o ?g. }

• W2916839666 endingPage "202" @default.
• W2916839666 startingPage "192" @default.
• W2916839666 abstract "Cardiovascular disease (CVD) is the main reason for premature death in patients with type 2 diabetes. Hyperglycemia, the hallmark of diabetes, has long been considered the link between diabetes and CVD, and many trials focused on preventing CVD manifestations by means of tight glucose control. However, diabetes is a multifactorial disease in which, e. g., insulin resistance, endothelial dysfunction, and factors such as hypertension and dyslipidemia contribute. Thus, treatment needs to be multifactorial and take cardiovascular aspects into account. Newer classes of drugs, originally launched for glucose lowering, among them dipeptidyl-peptidase (DPP)-4 inhibitors, sodium-glucose cotransporter (SGLT)-2 inhibitors, and glucagon-like peptide (GLP)-1 receptor agonists, have been studied in large cardiovascular outcome trials (CVOT). Several SGLT-2 inhibitors and GLP-1 receptor agonists are associated with a reduction of cardiovascular events (cardiovascular death, nonfatal myocardial infarction, and nonfatal stroke). Although the mechanisms behind the effects are not fully understood, an important reason for the benefits of SGLT-2 inhibitors seems be a reduction in heart failure, while GLP-1 receptor agonists may retard the development of the atherosclerotic vascular disease or may be effective by stabilizing plaques. The outcomes of these studies have been taken into account in recently issued guidelines and an important task for diabetologists, cardiologists, and general practitioners is to incorporate the findings of these trials into clinical practice." @default.
• W2916839666 created "2019-03-02" @default.
• W2916839666 creator A5030492424 @default.
• W2916839666 creator A5031807159 @default.
• W2916839666 creator A5082101100 @default.
• W2916839666 date "2019-02-25" @default.
• W2916839666 modified "2023-10-16" @default.
• W2916839666 title "Clinical implications of cardiovascular outcome trials in type 2 diabetes" @default.
• W2916839666 cites W1526927233 @default.
• W2916839666 cites W1534052272 @default.
• W2916839666 cites W172609984 @default.
• W2916839666 cites W1914420255 @default.
• W2916839666 cites W1973158237 @default.
• W2916839666 cites W1975663485 @default.
• W2916839666 cites W1977530623 @default.
• W2916839666 cites W1983269691 @default.
• W2916839666 cites W1987889845 @default.
• W2916839666 cites W2014759828 @default.
• W2916839666 cites W2024302114 @default.
• W2916839666 cites W2064130493 @default.
• W2916839666 cites W2073820461 @default.
• W2916839666 cites W2076573528 @default.
• W2916839666 cites W2090816085 @default.
• W2916839666 cites W2115271679 @default.
• W2916839666 cites W2123946565 @default.
• W2916839666 cites W2127125241 @default.
• W2916839666 cites W2127854619 @default.
• W2916839666 cites W2139634859 @default.
• W2916839666 cites W2139912326 @default.
• W2916839666 cites W2142830692 @default.
• W2916839666 cites W2144125787 @default.
• W2916839666 cites W2144423617 @default.
• W2916839666 cites W2146264128 @default.
• W2916839666 cites W2150561315 @default.
• W2916839666 cites W2158666727 @default.
• W2916839666 cites W2159087408 @default.
• W2916839666 cites W2159969745 @default.
• W2916839666 cites W2170271198 @default.
• W2916839666 cites W2171294019 @default.
• W2916839666 cites W2188846692 @default.
• W2916839666 cites W2271771390 @default.
• W2916839666 cites W2274836352 @default.
• W2916839666 cites W2282578582 @default.
• W2916839666 cites W2302447233 @default.
• W2916839666 cites W2337454357 @default.
• W2916839666 cites W2339857359 @default.
• W2916839666 cites W2346113118 @default.
• W2916839666 cites W2346794292 @default.
• W2916839666 cites W2425644022 @default.
• W2916839666 cites W2475233216 @default.
• W2916839666 cites W2513040800 @default.
• W2916839666 cites W2519510391 @default.
• W2916839666 cites W2625031949 @default.
• W2916839666 cites W2626446274 @default.
• W2916839666 cites W2735325912 @default.
• W2916839666 cites W2754041380 @default.
• W2916839666 cites W2806147248 @default.
• W2916839666 cites W2883137353 @default.
• W2916839666 cites W2894746763 @default.
• W2916839666 cites W2895533920 @default.
• W2916839666 cites W2900149048 @default.
• W2916839666 cites W2900413769 @default.
• W2916839666 cites W2907458346 @default.
• W2916839666 cites W3171237122 @default.
• W2916839666 cites W4297923916 @default.
• W2916839666 doi "https://doi.org/10.1007/s00059-019-4789-4" @default.
• W2916839666 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6507479" @default.
• W2916839666 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30805659" @default.
• W2916839666 hasPublicationYear "2019" @default.
• W2916839666 type Work @default.
• W2916839666 sameAs 2916839666 @default.
• W2916839666 citedByCount "4" @default.
• W2916839666 countsByYear W29168396662021 @default.
• W2916839666 countsByYear W29168396662022 @default.
• W2916839666 crossrefType "journal-article" @default.
• W2916839666 hasAuthorship W2916839666A5030492424 @default.
• W2916839666 hasAuthorship W2916839666A5031807159 @default.
• W2916839666 hasAuthorship W2916839666A5082101100 @default.
• W2916839666 hasBestOaLocation W29168396661 @default.
• W2916839666 hasConcept C126322002 @default.
• W2916839666 hasConcept C127413603 @default.
• W2916839666 hasConcept C134018914 @default.
• W2916839666 hasConcept C164705383 @default.
• W2916839666 hasConcept C177713679 @default.
• W2916839666 hasConcept C2777180221 @default.
• W2916839666 hasConcept C2777391703 @default.
• W2916839666 hasConcept C2778096610 @default.
• W2916839666 hasConcept C2778198053 @default.
• W2916839666 hasConcept C2778881409 @default.
• W2916839666 hasConcept C2779134260 @default.
• W2916839666 hasConcept C2780645631 @default.
• W2916839666 hasConcept C500558357 @default.
• W2916839666 hasConcept C535046627 @default.
• W2916839666 hasConcept C555293320 @default.
• W2916839666 hasConcept C60644358 @default.
• W2916839666 hasConcept C71924100 @default.
• W2916839666 hasConcept C78519656 @default.
• W2916839666 hasConcept C86803240 @default.

• next