Matches in SemOpenAlex for { <https://semopenalex.org/work/W2916849011> ?p ?o ?g. }
- W2916849011 endingPage "1087" @default.
- W2916849011 startingPage "1078" @default.
- W2916849011 abstract "Cardiovascular diseases (CVDs) are one of the leading causes of global morbidity and mortality. Among these, the ischemic heart disease (IHD) or coronary artery disease (CAD) accounts for the major deaths due to CVDs. Several approaches followed to treat the ischemic heart diseases are limited due to various adverse effects and cost of treatment. Recently, nanotechnology has revolutionized the field of biomedical research by introducing various technologies to improve the health care, using a nanomedicine approach. In this context, our group has well-established the europium hydroxide nanorods (EHNs), which promote the formation of new blood vessels (angiogenesis) through reactive oxygen species (ROS) and nitric oxide (NO)-mediated signaling pathways. Further, these pro-angiogenic nanorods were also reported to exhibit a mild to nontoxic nature toward mammalian cells and mouse models. Henceforth, in the present study, myocardial ischemia (MI) was created in Wistar rats using isoproterenol (ISO), a well-established model for investigating MI. For the first time, the effect of the pro-angiogenic nanorods (EHNs) on the ischemic condition was validated using several assays, which revealed that the ischemia and cardiotoxicity induced by ISO were ameliorated by EHNs in both H9C2 rat cardiomyocytes (in vitro) and Wistar rats (in vivo). Considering the above results, we believe that EHN could be developed as alternative treatment strategies for myocardial ischemia therapy and other ischemic diseases where angiogenesis plays a significant role, in the near future." @default.
- W2916849011 created "2019-03-02" @default.
- W2916849011 creator A5003099400 @default.
- W2916849011 creator A5029181368 @default.
- W2916849011 creator A5048827419 @default.
- W2916849011 creator A5067246815 @default.
- W2916849011 creator A5074076072 @default.
- W2916849011 creator A5081100739 @default.
- W2916849011 date "2019-02-20" @default.
- W2916849011 modified "2023-10-16" @default.
- W2916849011 title "Europium Hydroxide Nanorods (EHNs) Ameliorate Isoproterenol-Induced Myocardial Infarction: An <i>in Vitro</i> and <i>in Vivo</i> Investigation" @default.
- W2916849011 cites W1522247554 @default.
- W2916849011 cites W1936220942 @default.
- W2916849011 cites W1968236746 @default.
- W2916849011 cites W1981729984 @default.
- W2916849011 cites W1982514013 @default.
- W2916849011 cites W1982570312 @default.
- W2916849011 cites W1982830133 @default.
- W2916849011 cites W1997548509 @default.
- W2916849011 cites W2007425795 @default.
- W2916849011 cites W2011313485 @default.
- W2916849011 cites W2031061585 @default.
- W2916849011 cites W2039047287 @default.
- W2916849011 cites W2046348093 @default.
- W2916849011 cites W2060944117 @default.
- W2916849011 cites W2062121786 @default.
- W2916849011 cites W2064316640 @default.
- W2916849011 cites W2089035907 @default.
- W2916849011 cites W2091782127 @default.
- W2916849011 cites W2094176510 @default.
- W2916849011 cites W2098683031 @default.
- W2916849011 cites W2101450536 @default.
- W2916849011 cites W2118530283 @default.
- W2916849011 cites W2122741794 @default.
- W2916849011 cites W2125065061 @default.
- W2916849011 cites W2139109539 @default.
- W2916849011 cites W2141002407 @default.
- W2916849011 cites W2145974818 @default.
- W2916849011 cites W2147131254 @default.
- W2916849011 cites W2148892416 @default.
- W2916849011 cites W2157040346 @default.
- W2916849011 cites W2157456029 @default.
- W2916849011 cites W2488637612 @default.
- W2916849011 cites W2557061717 @default.
- W2916849011 cites W2601693710 @default.
- W2916849011 cites W2603417975 @default.
- W2916849011 cites W2605922486 @default.
- W2916849011 cites W2609170681 @default.
- W2916849011 cites W2610713452 @default.
- W2916849011 cites W2613412363 @default.
- W2916849011 cites W2616642355 @default.
- W2916849011 cites W2620735567 @default.
- W2916849011 cites W2620784243 @default.
- W2916849011 cites W2624904709 @default.
- W2916849011 cites W2734390831 @default.
- W2916849011 cites W2738861968 @default.
- W2916849011 cites W2740343873 @default.
- W2916849011 cites W2768873441 @default.
- W2916849011 cites W2806331530 @default.
- W2916849011 cites W2810218508 @default.
- W2916849011 doi "https://doi.org/10.1021/acsabm.8b00669" @default.
- W2916849011 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35021358" @default.
- W2916849011 hasPublicationYear "2019" @default.
- W2916849011 type Work @default.
- W2916849011 sameAs 2916849011 @default.
- W2916849011 citedByCount "13" @default.
- W2916849011 countsByYear W29168490112019 @default.
- W2916849011 countsByYear W29168490112020 @default.
- W2916849011 countsByYear W29168490112021 @default.
- W2916849011 countsByYear W29168490112022 @default.
- W2916849011 countsByYear W29168490112023 @default.
- W2916849011 crossrefType "journal-article" @default.
- W2916849011 hasAuthorship W2916849011A5003099400 @default.
- W2916849011 hasAuthorship W2916849011A5029181368 @default.
- W2916849011 hasAuthorship W2916849011A5048827419 @default.
- W2916849011 hasAuthorship W2916849011A5067246815 @default.
- W2916849011 hasAuthorship W2916849011A5074076072 @default.
- W2916849011 hasAuthorship W2916849011A5081100739 @default.
- W2916849011 hasConcept C126322002 @default.
- W2916849011 hasConcept C15083742 @default.
- W2916849011 hasConcept C150903083 @default.
- W2916849011 hasConcept C151730666 @default.
- W2916849011 hasConcept C155672457 @default.
- W2916849011 hasConcept C164705383 @default.
- W2916849011 hasConcept C171250308 @default.
- W2916849011 hasConcept C192562407 @default.
- W2916849011 hasConcept C207001950 @default.
- W2916849011 hasConcept C2776694085 @default.
- W2916849011 hasConcept C2778213512 @default.
- W2916849011 hasConcept C2778233292 @default.
- W2916849011 hasConcept C2779343474 @default.
- W2916849011 hasConcept C2780394083 @default.
- W2916849011 hasConcept C500558357 @default.
- W2916849011 hasConcept C519581460 @default.
- W2916849011 hasConcept C541997718 @default.
- W2916849011 hasConcept C71924100 @default.
- W2916849011 hasConcept C86803240 @default.
- W2916849011 hasConcept C98274493 @default.