Matches in SemOpenAlex for { <https://semopenalex.org/work/W2916857891> ?p ?o ?g. }
Showing items 1 to 78 of
78
with 100 items per page.
- W2916857891 abstract "ProblemThe aim of this study was to examine if allergic rhinitis and nasal polyposis are associated with the level of surfactant protein-A. MethodsSinus mucosal biopsies were performed in patients with allergic rhinitis (n= 15), nasal polyposis (n=21) and controls (n= 10). Immunolocalization of surfactant protein was performed with antibodies to SP-A using Streptavidin Peroxidase Conjugated Method and indirect immunofluorescence method. Blood serums were obtained from three subjects in each group for enzyme-linked immunosorbent assay (ELISA) analysis of surfactant protein-A. ResultsBy ELISA, AR (n =15) and NP (n = 21) showed significantly decreased levels of SP-A when compared with controls (n= 10), although these two groups were not statistically significant. Immunohistochemical investigation showed intense SP-A staining in the nasal epithelium of each groups, but weak staining in patients with AR and NP. ConclusionWe report for the first time the expression of SP-A in both diseased and normal nasal mucosa using the indirect immunofluorescence method. There was an inverse relation between surfactant protein-A levels and symptoms and signs of rhinitis in patients with AR and NP. SignificanceSP-A may play a defensive role in the chronic inflammatory diseases of upper airway. Understanding the exact role of SP-A in the upper airway diseases will help develop novel treatment approaches for sinonasal pathoses." @default.
- W2916857891 created "2019-03-02" @default.
- W2916857891 creator A5037579252 @default.
- W2916857891 creator A5062278651 @default.
- W2916857891 creator A5075472743 @default.
- W2916857891 date "2008-08-01" @default.
- W2916857891 modified "2023-09-26" @default.
- W2916857891 title "R460 – Relation Between SPA and Symptoms of Patients With AR and NP" @default.
- W2916857891 doi "https://doi.org/10.1016/j.otohns.2008.05.619" @default.
- W2916857891 hasPublicationYear "2008" @default.
- W2916857891 type Work @default.
- W2916857891 sameAs 2916857891 @default.
- W2916857891 citedByCount "0" @default.
- W2916857891 crossrefType "journal-article" @default.
- W2916857891 hasAuthorship W2916857891A5037579252 @default.
- W2916857891 hasAuthorship W2916857891A5062278651 @default.
- W2916857891 hasAuthorship W2916857891A5075472743 @default.
- W2916857891 hasConcept C105922876 @default.
- W2916857891 hasConcept C126322002 @default.
- W2916857891 hasConcept C136449434 @default.
- W2916857891 hasConcept C141071460 @default.
- W2916857891 hasConcept C142724271 @default.
- W2916857891 hasConcept C159654299 @default.
- W2916857891 hasConcept C185592680 @default.
- W2916857891 hasConcept C194108754 @default.
- W2916857891 hasConcept C203014093 @default.
- W2916857891 hasConcept C204232928 @default.
- W2916857891 hasConcept C2777438239 @default.
- W2916857891 hasConcept C2777714996 @default.
- W2916857891 hasConcept C2778236600 @default.
- W2916857891 hasConcept C2984894117 @default.
- W2916857891 hasConcept C55493867 @default.
- W2916857891 hasConcept C58226133 @default.
- W2916857891 hasConcept C59377437 @default.
- W2916857891 hasConcept C71924100 @default.
- W2916857891 hasConcept C74864618 @default.
- W2916857891 hasConcept C8891405 @default.
- W2916857891 hasConcept C90924648 @default.
- W2916857891 hasConceptScore W2916857891C105922876 @default.
- W2916857891 hasConceptScore W2916857891C126322002 @default.
- W2916857891 hasConceptScore W2916857891C136449434 @default.
- W2916857891 hasConceptScore W2916857891C141071460 @default.
- W2916857891 hasConceptScore W2916857891C142724271 @default.
- W2916857891 hasConceptScore W2916857891C159654299 @default.
- W2916857891 hasConceptScore W2916857891C185592680 @default.
- W2916857891 hasConceptScore W2916857891C194108754 @default.
- W2916857891 hasConceptScore W2916857891C203014093 @default.
- W2916857891 hasConceptScore W2916857891C204232928 @default.
- W2916857891 hasConceptScore W2916857891C2777438239 @default.
- W2916857891 hasConceptScore W2916857891C2777714996 @default.
- W2916857891 hasConceptScore W2916857891C2778236600 @default.
- W2916857891 hasConceptScore W2916857891C2984894117 @default.
- W2916857891 hasConceptScore W2916857891C55493867 @default.
- W2916857891 hasConceptScore W2916857891C58226133 @default.
- W2916857891 hasConceptScore W2916857891C59377437 @default.
- W2916857891 hasConceptScore W2916857891C71924100 @default.
- W2916857891 hasConceptScore W2916857891C74864618 @default.
- W2916857891 hasConceptScore W2916857891C8891405 @default.
- W2916857891 hasConceptScore W2916857891C90924648 @default.
- W2916857891 hasIssue "S2" @default.
- W2916857891 hasLocation W29168578911 @default.
- W2916857891 hasOpenAccess W2916857891 @default.
- W2916857891 hasPrimaryLocation W29168578911 @default.
- W2916857891 hasRelatedWork W1990910225 @default.
- W2916857891 hasRelatedWork W1999016335 @default.
- W2916857891 hasRelatedWork W2004170831 @default.
- W2916857891 hasRelatedWork W2021548813 @default.
- W2916857891 hasRelatedWork W2035464821 @default.
- W2916857891 hasRelatedWork W2080788616 @default.
- W2916857891 hasRelatedWork W2087936264 @default.
- W2916857891 hasRelatedWork W2147831483 @default.
- W2916857891 hasRelatedWork W2916857891 @default.
- W2916857891 hasRelatedWork W3126707439 @default.
- W2916857891 hasVolume "139" @default.
- W2916857891 isParatext "false" @default.
- W2916857891 isRetracted "false" @default.
- W2916857891 magId "2916857891" @default.
- W2916857891 workType "article" @default.