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• W2916939527 abstract "Enantioenriched aldehydes are produced through asymmetric hydroformylation of styrene derivatives using BIBOP-type ligands. The featured example is enantioselective synthesis of 4-methyl-3,4-dihydroisocoumarin, which was prepared in a 95.1:4.9 enantiomeric ratio from asymmetric hydroformylation of ethyl 2-vinylbenzoate followed by in situ lactonization during the reduction process. The conditions are compatible with both electron-rich and electron-poor substituents." @default.
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• W2916939527 date "2019-02-19" @default.
• W2916939527 modified "2023-10-14" @default.
• W2916939527 title "Enantioselective Synthesis of 4-Methyl-3,4-dihydroisocoumarin via Asymmetric Hydroformylation of Styrene Derivatives" @default.
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• W2916939527 doi "https://doi.org/10.1021/acs.joc.8b02813" @default.
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