Matches in SemOpenAlex for { <https://semopenalex.org/work/W2917444168> ?p ?o ?g. }
- W2917444168 endingPage "67" @default.
- W2917444168 startingPage "62" @default.
- W2917444168 abstract "This work used 3,4,9,10-perylenetetracarboxylic acid-luminol composite (PTCA-luminol) as signal tag with improved ECL signal and applied cruciform DNA structure mediated exponential strand displacement reaction (SDR) to construct an ultrasensitive electrochemiluminescence (ECL) biosensor for microRNA-21 (miRNA-21) detection. The novel luminol-based signal tags was synthesized utilizing the π-π stacking interaction between PTCA and luminol, realizing highly effective and stable immobilization of luminol and resulting in good stability and strong ECL response. Meanwhile, target miRNA-21 triggered disaggregation of cruciform DNA structure was used to mediate exponential SDR for target recycling amplification. Taking advantage of the novel luminol-based signal tag and exponential SDR, the proposed ECL biosensor achieved excellent sensitivity with wide linear range from 10 aM to 100 pM and detection limit was 2 aM. Moreover, this ECL biosensor was applied to estimate the expression level of miRNA-21 and pharmacodynamics of matrine in human breast cancer cells (MCF-7 cells). The proposed biosensor provided a new opportunity for the preparation of ECL nanomaterials and exhibited great application potential in other biomarkers detection, clinical application and pharmacodynamics evaluation." @default.
- W2917444168 created "2019-03-02" @default.
- W2917444168 creator A5026154658 @default.
- W2917444168 creator A5033684035 @default.
- W2917444168 creator A5055505843 @default.
- W2917444168 creator A5057795872 @default.
- W2917444168 creator A5063870450 @default.
- W2917444168 creator A5075456604 @default.
- W2917444168 date "2019-05-01" @default.
- W2917444168 modified "2023-10-18" @default.
- W2917444168 title "Highly-efficient luminol immobilization approach and exponential strand displacement reaction based electrochemiluminescent strategy for monitoring microRNA expression in cell" @default.
- W2917444168 cites W1650481969 @default.
- W2917444168 cites W1770611730 @default.
- W2917444168 cites W1990078858 @default.
- W2917444168 cites W1996923356 @default.
- W2917444168 cites W2008262280 @default.
- W2917444168 cites W2066081299 @default.
- W2917444168 cites W2098584669 @default.
- W2917444168 cites W2103211592 @default.
- W2917444168 cites W2129330594 @default.
- W2917444168 cites W2141615308 @default.
- W2917444168 cites W2144253455 @default.
- W2917444168 cites W2156476859 @default.
- W2917444168 cites W2200504012 @default.
- W2917444168 cites W2318267179 @default.
- W2917444168 cites W2322049100 @default.
- W2917444168 cites W2327218239 @default.
- W2917444168 cites W2336375238 @default.
- W2917444168 cites W2339164603 @default.
- W2917444168 cites W2341908201 @default.
- W2917444168 cites W2346309772 @default.
- W2917444168 cites W2467832899 @default.
- W2917444168 cites W2515083824 @default.
- W2917444168 cites W2580095184 @default.
- W2917444168 cites W2583428319 @default.
- W2917444168 cites W2589249520 @default.
- W2917444168 cites W2602614828 @default.
- W2917444168 cites W2609622939 @default.
- W2917444168 cites W2610068365 @default.
- W2917444168 cites W2664462862 @default.
- W2917444168 cites W2737356908 @default.
- W2917444168 cites W2746779421 @default.
- W2917444168 cites W2747389346 @default.
- W2917444168 cites W2748133704 @default.
- W2917444168 cites W2748205671 @default.
- W2917444168 cites W2779383593 @default.
- W2917444168 cites W2782074095 @default.
- W2917444168 cites W2889737384 @default.
- W2917444168 cites W2898436134 @default.
- W2917444168 doi "https://doi.org/10.1016/j.bios.2019.02.005" @default.
- W2917444168 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30856428" @default.
- W2917444168 hasPublicationYear "2019" @default.
- W2917444168 type Work @default.
- W2917444168 sameAs 2917444168 @default.
- W2917444168 citedByCount "19" @default.
- W2917444168 countsByYear W29174441682019 @default.
- W2917444168 countsByYear W29174441682020 @default.
- W2917444168 countsByYear W29174441682021 @default.
- W2917444168 countsByYear W29174441682022 @default.
- W2917444168 countsByYear W29174441682023 @default.
- W2917444168 crossrefType "journal-article" @default.
- W2917444168 hasAuthorship W2917444168A5026154658 @default.
- W2917444168 hasAuthorship W2917444168A5033684035 @default.
- W2917444168 hasAuthorship W2917444168A5055505843 @default.
- W2917444168 hasAuthorship W2917444168A5057795872 @default.
- W2917444168 hasAuthorship W2917444168A5063870450 @default.
- W2917444168 hasAuthorship W2917444168A5075456604 @default.
- W2917444168 hasConcept C10349863 @default.
- W2917444168 hasConcept C119128265 @default.
- W2917444168 hasConcept C145802702 @default.
- W2917444168 hasConcept C160756335 @default.
- W2917444168 hasConcept C185592680 @default.
- W2917444168 hasConcept C2776316542 @default.
- W2917444168 hasConcept C38965407 @default.
- W2917444168 hasConcept C43617362 @default.
- W2917444168 hasConcept C55493867 @default.
- W2917444168 hasConceptScore W2917444168C10349863 @default.
- W2917444168 hasConceptScore W2917444168C119128265 @default.
- W2917444168 hasConceptScore W2917444168C145802702 @default.
- W2917444168 hasConceptScore W2917444168C160756335 @default.
- W2917444168 hasConceptScore W2917444168C185592680 @default.
- W2917444168 hasConceptScore W2917444168C2776316542 @default.
- W2917444168 hasConceptScore W2917444168C38965407 @default.
- W2917444168 hasConceptScore W2917444168C43617362 @default.
- W2917444168 hasConceptScore W2917444168C55493867 @default.
- W2917444168 hasFunder F4320321001 @default.
- W2917444168 hasLocation W29174441681 @default.
- W2917444168 hasLocation W29174441682 @default.
- W2917444168 hasOpenAccess W2917444168 @default.
- W2917444168 hasPrimaryLocation W29174441681 @default.
- W2917444168 hasRelatedWork W1976486319 @default.
- W2917444168 hasRelatedWork W2033449957 @default.
- W2917444168 hasRelatedWork W2065285972 @default.
- W2917444168 hasRelatedWork W2362479462 @default.
- W2917444168 hasRelatedWork W2512544230 @default.
- W2917444168 hasRelatedWork W2950162684 @default.
- W2917444168 hasRelatedWork W2980154840 @default.
- W2917444168 hasRelatedWork W2986923691 @default.