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- W2917492111 abstract "Preterm infants are at greater risk of microbial insult than full-term infants, including reduced exposure to maternal vaginal and enteric microbes, higher rates of formula feeding, invasive procedures, and administration of antibiotics and medications that alter gastrointestinal pH. This investigation of the VLBW infant microbiome over the course of the neonatal intensive care unit (NICU) stay, and at ages 2 and 4 years, showed that the only clinical variables associated with significant differences in taxon abundance were weight gain during NICU stay ( Klebsiella and Staphylococcus ) and antibiotic administration ( Streptococcus and Bifidobacterium ). At 2 and 4 years of age, the microbiota of these VLBW infants became similar to the mothers’ microbiota. The number of microbial taxa shared between the infant or toddler and the mother varied, with least the overlap between infants and mothers. Overall, there was a significant association between the diversity and structure of the microbial community and infant weight and length gain in an at-risk childhood population." @default.
- W2917492111 created "2019-03-02" @default.
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- W2917492111 date "2019-02-26" @default.
- W2917492111 modified "2023-10-18" @default.
- W2917492111 title "Longitudinal Microbiome Composition and Stability Correlate with Increased Weight and Length of Very-Low-Birth-Weight Infants" @default.
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- W2917492111 doi "https://doi.org/10.1128/msystems.00229-18" @default.
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