FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2917538021> ?p ?o ?g. }

• W2917538021 abstract "Abstract Synthetic biology based on bacteria has been displayed in antitumor therapy and shown good performance. In this study, an engineered bacterium Escherichia coli MG1655 is designed with NDH‐2 enzyme (respiratory chain enzyme II) overexpression (Ec‐pE), which can colonize in tumor regions and increase localized H 2 O 2 generation. Following from this, magnetic Fe 3 O 4 nanoparticles are covalently linked to bacteria to act as a catalyst for a Fenton‐like reaction, which converts H 2 O 2 to toxic hydroxyl radicals (•OH) for tumor therapy. In this constructed bioreactor, the Fenton‐like reaction occurs with sustainably synthesized H 2 O 2 produced by engineered bacteria, and severe tumor apoptosis is induced via the produced toxic •OH. These results show that this bioreactor can achieve effective tumor colonization, and realize a self‐supplied therapeutic Fenton‐like reaction without additional H 2 O 2 provision." @default.
• W2917538021 created "2019-03-02" @default.
• W2917538021 creator A5022812355 @default.
• W2917538021 creator A5034515596 @default.
• W2917538021 creator A5038811887 @default.
• W2917538021 creator A5047428207 @default.
• W2917538021 creator A5053792879 @default.
• W2917538021 creator A5058399592 @default.
• W2917538021 creator A5064634628 @default.
• W2917538021 creator A5069099639 @default.
• W2917538021 creator A5075557728 @default.
• W2917538021 creator A5080779729 @default.
• W2917538021 date "2019-02-25" @default.
• W2917538021 modified "2023-10-16" @default.
• W2917538021 title "Engineered Bacterial Bioreactor for Tumor Therapy via Fenton‐Like Reaction with Localized H₂O₂ Generation" @default.
• W2917538021 cites W1835465815 @default.
• W2917538021 cites W1921909110 @default.
• W2917538021 cites W1979507175 @default.
• W2917538021 cites W1988985710 @default.
• W2917538021 cites W2032651140 @default.
• W2917538021 cites W2034200782 @default.
• W2917538021 cites W2042595128 @default.
• W2917538021 cites W2054484446 @default.
• W2917538021 cites W2062318924 @default.
• W2917538021 cites W2082792779 @default.
• W2917538021 cites W2123958837 @default.
• W2917538021 cites W2141564052 @default.
• W2917538021 cites W2162853190 @default.
• W2917538021 cites W2167862219 @default.
• W2917538021 cites W2246562916 @default.
• W2917538021 cites W2346043912 @default.
• W2917538021 cites W2480697384 @default.
• W2917538021 cites W2515051096 @default.
• W2917538021 cites W2550813149 @default.
• W2917538021 cites W2558943593 @default.
• W2917538021 cites W2586484796 @default.
• W2917538021 cites W2604529579 @default.
• W2917538021 cites W2625655597 @default.
• W2917538021 cites W2734854413 @default.
• W2917538021 cites W2783392188 @default.
• W2917538021 cites W2793503277 @default.
• W2917538021 cites W2794224913 @default.
• W2917538021 cites W2797507121 @default.
• W2917538021 cites W2800987852 @default.
• W2917538021 cites W2804958847 @default.
• W2917538021 cites W2808758302 @default.
• W2917538021 cites W2897382512 @default.
• W2917538021 cites W2899114650 @default.
• W2917538021 cites W2900578714 @default.
• W2917538021 doi "https://doi.org/10.1002/adma.201808278" @default.
• W2917538021 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30803049" @default.
• W2917538021 hasPublicationYear "2019" @default.
• W2917538021 type Work @default.
• W2917538021 sameAs 2917538021 @default.
• W2917538021 citedByCount "236" @default.
• W2917538021 countsByYear W29175380212019 @default.
• W2917538021 countsByYear W29175380212020 @default.
• W2917538021 countsByYear W29175380212021 @default.
• W2917538021 countsByYear W29175380212022 @default.
• W2917538021 countsByYear W29175380212023 @default.
• W2917538021 crossrefType "journal-article" @default.
• W2917538021 hasAuthorship W2917538021A5022812355 @default.
• W2917538021 hasAuthorship W2917538021A5034515596 @default.
• W2917538021 hasAuthorship W2917538021A5038811887 @default.
• W2917538021 hasAuthorship W2917538021A5047428207 @default.
• W2917538021 hasAuthorship W2917538021A5053792879 @default.
• W2917538021 hasAuthorship W2917538021A5058399592 @default.
• W2917538021 hasAuthorship W2917538021A5064634628 @default.
• W2917538021 hasAuthorship W2917538021A5069099639 @default.
• W2917538021 hasAuthorship W2917538021A5075557728 @default.
• W2917538021 hasAuthorship W2917538021A5080779729 @default.
• W2917538021 hasConcept C104317684 @default.
• W2917538021 hasConcept C139066938 @default.
• W2917538021 hasConcept C155672457 @default.
• W2917538021 hasConcept C161790260 @default.
• W2917538021 hasConcept C168170006 @default.
• W2917538021 hasConcept C171250308 @default.
• W2917538021 hasConcept C178790620 @default.
• W2917538021 hasConcept C181199279 @default.
• W2917538021 hasConcept C185592680 @default.
• W2917538021 hasConcept C192562407 @default.
• W2917538021 hasConcept C21951064 @default.
• W2917538021 hasConcept C2993040405 @default.
• W2917538021 hasConcept C523546767 @default.
• W2917538021 hasConcept C54355233 @default.
• W2917538021 hasConcept C547475151 @default.
• W2917538021 hasConcept C55493867 @default.
• W2917538021 hasConcept C86803240 @default.
• W2917538021 hasConcept C89423630 @default.
• W2917538021 hasConceptScore W2917538021C104317684 @default.
• W2917538021 hasConceptScore W2917538021C139066938 @default.
• W2917538021 hasConceptScore W2917538021C155672457 @default.
• W2917538021 hasConceptScore W2917538021C161790260 @default.
• W2917538021 hasConceptScore W2917538021C168170006 @default.
• W2917538021 hasConceptScore W2917538021C171250308 @default.
• W2917538021 hasConceptScore W2917538021C178790620 @default.
• W2917538021 hasConceptScore W2917538021C181199279 @default.
• W2917538021 hasConceptScore W2917538021C185592680 @default.
• W2917538021 hasConceptScore W2917538021C192562407 @default.
• W2917538021 hasConceptScore W2917538021C21951064 @default.

• next