FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2917569531> ?p ?o ?g. }

• W2917569531 endingPage "1282" @default.
• W2917569531 startingPage "1273" @default.
• W2917569531 abstract "Abstract Background Microbial shifts have been associated with disease activity in Crohn’s disease [CD], but findings on specific taxa are inconsistent. This may be due to differences in applied methods and cross-sectional study designs. We prospectively examined the faecal microbiota in adult CD patients with changing or stable disease course over time. Methods Faeces were collected at two time-points from 15 healthy control individuals [HCs], 35 CD patients who were in remission and who maintained remission [RRs], and 22 CD patients during remission and also during subsequent exacerbation [RAs]. The microbial composition was assessed by 16S rRNA [V4] gene sequencing. Results Compared with HCs, patients with CD had a lower microbial richness [p = 0.0002] and diversity [p = 0.005]. Moreover, the microbial community structure of a subset of patients, clustered apart from HCs, was characterized by low microbial diversity and Faecalibacterium abundance. Patients within this cluster did not differ with respect to long-term disease course compared with patients with a ‘healthy-appearing’ microbiota. Over time, microbial richness and diversity did not change in RR versus RA patients. Although the microbial community structure of both RR and RA patients was less stable over time compared with that of HCs, no differences were observed between the patient groups [p = 0.17]; nor was the stability impacted by Montreal classification, medication use, or surgery. Conclusion The altered microbiota composition and stability in CD was neither associated with disease activity nor long-term disease course, questioning its involvement in the development of an exacerbation. The aberrant microbiota composition in a subset of CD patients warrants further exploration of a more microbiota-driven etiology in this group." @default.
• W2917569531 created "2019-03-02" @default.
• W2917569531 creator A5001770368 @default.
• W2917569531 creator A5038737152 @default.
• W2917569531 creator A5050638372 @default.
• W2917569531 creator A5056341837 @default.
• W2917569531 creator A5058784327 @default.
• W2917569531 creator A5065028617 @default.
• W2917569531 creator A5069798085 @default.
• W2917569531 creator A5087592132 @default.
• W2917569531 creator A5090502596 @default.
• W2917569531 date "2019-02-27" @default.
• W2917569531 modified "2023-10-15" @default.
• W2917569531 title "Faecal Microbiota Dynamics and their Relation to Disease Course in Crohn’s Disease" @default.
• W2917569531 cites W1563930908 @default.
• W2917569531 cites W1569647046 @default.
• W2917569531 cites W1868032452 @default.
• W2917569531 cites W2004192158 @default.
• W2917569531 cites W2004608617 @default.
• W2917569531 cites W2021559015 @default.
• W2917569531 cites W2028520715 @default.
• W2917569531 cites W2030032384 @default.
• W2917569531 cites W2034008046 @default.
• W2917569531 cites W2054755479 @default.
• W2917569531 cites W2056585868 @default.
• W2917569531 cites W2064958296 @default.
• W2917569531 cites W2085284704 @default.
• W2917569531 cites W2088608269 @default.
• W2917569531 cites W2090711753 @default.
• W2917569531 cites W2097788076 @default.
• W2917569531 cites W2097875133 @default.
• W2917569531 cites W2102013054 @default.
• W2917569531 cites W2102567329 @default.
• W2917569531 cites W2107805776 @default.
• W2917569531 cites W2112635226 @default.
• W2917569531 cites W2122242590 @default.
• W2917569531 cites W2123914286 @default.
• W2917569531 cites W2131042289 @default.
• W2917569531 cites W2143777796 @default.
• W2917569531 cites W2144413511 @default.
• W2917569531 cites W2146584127 @default.
• W2917569531 cites W2155660329 @default.
• W2917569531 cites W2155860422 @default.
• W2917569531 cites W2159561736 @default.
• W2917569531 cites W2162748874 @default.
• W2917569531 cites W2209396357 @default.
• W2917569531 cites W2255712021 @default.
• W2917569531 cites W2578250538 @default.
• W2917569531 cites W2586959160 @default.
• W2917569531 cites W2588997555 @default.
• W2917569531 cites W2626326831 @default.
• W2917569531 cites W812505777 @default.
• W2917569531 doi "https://doi.org/10.1093/ecco-jcc/jjz049" @default.
• W2917569531 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6764104" @default.
• W2917569531 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30810207" @default.
• W2917569531 hasPublicationYear "2019" @default.
• W2917569531 type Work @default.
• W2917569531 sameAs 2917569531 @default.
• W2917569531 citedByCount "33" @default.
• W2917569531 countsByYear W29175695312019 @default.
• W2917569531 countsByYear W29175695312020 @default.
• W2917569531 countsByYear W29175695312021 @default.
• W2917569531 countsByYear W29175695312022 @default.
• W2917569531 countsByYear W29175695312023 @default.
• W2917569531 crossrefType "journal-article" @default.
• W2917569531 hasAuthorship W2917569531A5001770368 @default.
• W2917569531 hasAuthorship W2917569531A5038737152 @default.
• W2917569531 hasAuthorship W2917569531A5050638372 @default.
• W2917569531 hasAuthorship W2917569531A5056341837 @default.
• W2917569531 hasAuthorship W2917569531A5058784327 @default.
• W2917569531 hasAuthorship W2917569531A5065028617 @default.
• W2917569531 hasAuthorship W2917569531A5069798085 @default.
• W2917569531 hasAuthorship W2917569531A5087592132 @default.
• W2917569531 hasAuthorship W2917569531A5090502596 @default.
• W2917569531 hasBestOaLocation W29175695311 @default.
• W2917569531 hasConcept C126322002 @default.
• W2917569531 hasConcept C143121216 @default.
• W2917569531 hasConcept C18903297 @default.
• W2917569531 hasConcept C203014093 @default.
• W2917569531 hasConcept C2777014857 @default.
• W2917569531 hasConcept C2777165150 @default.
• W2917569531 hasConcept C2778260677 @default.
• W2917569531 hasConcept C2779134260 @default.
• W2917569531 hasConcept C2779280984 @default.
• W2917569531 hasConcept C2780675110 @default.
• W2917569531 hasConcept C2780940764 @default.
• W2917569531 hasConcept C523546767 @default.
• W2917569531 hasConcept C53565203 @default.
• W2917569531 hasConcept C539455810 @default.
• W2917569531 hasConcept C54355233 @default.
• W2917569531 hasConcept C60644358 @default.
• W2917569531 hasConcept C61716771 @default.
• W2917569531 hasConcept C71924100 @default.
• W2917569531 hasConcept C86803240 @default.
• W2917569531 hasConcept C89423630 @default.
• W2917569531 hasConcept C90924648 @default.
• W2917569531 hasConceptScore W2917569531C126322002 @default.
• W2917569531 hasConceptScore W2917569531C143121216 @default.

• next