FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2917730648> ?p ?o ?g. }

• W2917730648 endingPage "16" @default.
• W2917730648 startingPage "10" @default.
• W2917730648 abstract "OBJECTIVE There is a strong clinical need to accurately determine the average annual hemorrhage risk in unruptured brain arteriovenous malformations (AVMs). This need motivated the present initiative to use data from a uniquely large patient population and design a novel methodology to achieve a risk determination with unprecedented accuracy. The authors also aimed to determine the impact of sex, pregnancy, AVM volume, and location on the risk for AVM rupture. METHODS The present study does not consider any specific management of the AVMs, but only uses the age distribution for the first hemorrhage, the shape of which becomes universal for a sufficiently large set of patients. For this purpose, the authors collected observations, including age at first hemorrhage and AVM size and location, in 3425 patients. The average annual risk for hemorrhage could then be determined from the simple relation that the number of patients with their first hemorrhage at a specific age equals the risk for hemorrhage times the number of patients at risk at that age. For a subset of the patients, the information regarding occurrence of AVM hemorrhage after treatment of the first hemorrhage was used for further analysis of the influence on risk from AVM location and pregnancy. RESULTS The age distribution for the first AVM hemorrhage was used to determine the average annual risk for hemorrhage in unruptured AVMs at adult ages (25–60 years). It was concluded to be 3.1% ± 0.2% and unrelated to AVM volume but influenced by its location, with the highest risk for centrally located AVMs. The hemorrhage risk was found to be significantly higher for females in their fertile years. CONCLUSIONS The present methodology allowed the authors to determine the average annual risk for the first AVM hemorrhage at 3.1% ± 0.2% without the need for individual patient follow-up. This methodology has potential also for other similar types of investigations. The conclusion that centrally located AVMs carry a higher risk was confirmed by follow-up information. Follow-up information was also used to conclude that pregnancy causes a substantially greater AVM hemorrhage risk. The age distribution for AVM hemorrhage is incompatible with AVMs present at birth having the same hemorrhage risk as AVMs in adults. Plausibly, they instead develop in the early years of life, possibly with a lower hemorrhage risk during that time period." @default.
• W2917730648 created "2019-03-02" @default.
• W2917730648 creator A5001959228 @default.
• W2917730648 creator A5002750718 @default.
• W2917730648 creator A5004877841 @default.
• W2917730648 creator A5006571598 @default.
• W2917730648 creator A5019910065 @default.
• W2917730648 creator A5027994732 @default.
• W2917730648 creator A5032612533 @default.
• W2917730648 creator A5035692256 @default.
• W2917730648 creator A5039781666 @default.
• W2917730648 creator A5046359356 @default.
• W2917730648 creator A5047858866 @default.
• W2917730648 creator A5063738165 @default.
• W2917730648 creator A5082451414 @default.
• W2917730648 creator A5089995737 @default.
• W2917730648 date "2018-12-01" @default.
• W2917730648 modified "2023-10-18" @default.
• W2917730648 title "A novel method to determine the natural course of unruptured brain arteriovenous malformations without the need for follow-up information" @default.
• W2917730648 cites W1965061510 @default.
• W2917730648 cites W1972656667 @default.
• W2917730648 cites W1982437710 @default.
• W2917730648 cites W2013663435 @default.
• W2917730648 cites W2048020454 @default.
• W2917730648 cites W2050529289 @default.
• W2917730648 cites W2052619669 @default.
• W2917730648 cites W2055825000 @default.
• W2917730648 cites W2066788634 @default.
• W2917730648 cites W2070982129 @default.
• W2917730648 cites W2084000811 @default.
• W2917730648 cites W2084725426 @default.
• W2917730648 cites W2100788029 @default.
• W2917730648 cites W2102766489 @default.
• W2917730648 cites W2105301891 @default.
• W2917730648 cites W2115273358 @default.
• W2917730648 cites W2124599330 @default.
• W2917730648 cites W2130187335 @default.
• W2917730648 cites W2130774572 @default.
• W2917730648 cites W2154970859 @default.
• W2917730648 cites W2261136219 @default.
• W2917730648 cites W2533825452 @default.
• W2917730648 cites W2586777038 @default.
• W2917730648 cites W2616943652 @default.
• W2917730648 cites W2621946351 @default.
• W2917730648 cites W4376595656 @default.
• W2917730648 cites W9932100 @default.
• W2917730648 doi "https://doi.org/10.3171/2018.7.gks181278" @default.
• W2917730648 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30544301" @default.
• W2917730648 hasPublicationYear "2018" @default.
• W2917730648 type Work @default.
• W2917730648 sameAs 2917730648 @default.
• W2917730648 citedByCount "10" @default.
• W2917730648 countsByYear W29177306482020 @default.
• W2917730648 countsByYear W29177306482022 @default.
• W2917730648 countsByYear W29177306482023 @default.
• W2917730648 crossrefType "journal-article" @default.
• W2917730648 hasAuthorship W2917730648A5001959228 @default.
• W2917730648 hasAuthorship W2917730648A5002750718 @default.
• W2917730648 hasAuthorship W2917730648A5004877841 @default.
• W2917730648 hasAuthorship W2917730648A5006571598 @default.
• W2917730648 hasAuthorship W2917730648A5019910065 @default.
• W2917730648 hasAuthorship W2917730648A5027994732 @default.
• W2917730648 hasAuthorship W2917730648A5032612533 @default.
• W2917730648 hasAuthorship W2917730648A5035692256 @default.
• W2917730648 hasAuthorship W2917730648A5039781666 @default.
• W2917730648 hasAuthorship W2917730648A5046359356 @default.
• W2917730648 hasAuthorship W2917730648A5047858866 @default.
• W2917730648 hasAuthorship W2917730648A5063738165 @default.
• W2917730648 hasAuthorship W2917730648A5082451414 @default.
• W2917730648 hasAuthorship W2917730648A5089995737 @default.
• W2917730648 hasBestOaLocation W29177306481 @default.
• W2917730648 hasConcept C141071460 @default.
• W2917730648 hasConcept C2778749279 @default.
• W2917730648 hasConcept C2779234561 @default.
• W2917730648 hasConcept C2779603958 @default.
• W2917730648 hasConcept C2780643987 @default.
• W2917730648 hasConcept C2908647359 @default.
• W2917730648 hasConcept C2910939485 @default.
• W2917730648 hasConcept C54355233 @default.
• W2917730648 hasConcept C71924100 @default.
• W2917730648 hasConcept C86803240 @default.
• W2917730648 hasConcept C99454951 @default.
• W2917730648 hasConceptScore W2917730648C141071460 @default.
• W2917730648 hasConceptScore W2917730648C2778749279 @default.
• W2917730648 hasConceptScore W2917730648C2779234561 @default.
• W2917730648 hasConceptScore W2917730648C2779603958 @default.
• W2917730648 hasConceptScore W2917730648C2780643987 @default.
• W2917730648 hasConceptScore W2917730648C2908647359 @default.
• W2917730648 hasConceptScore W2917730648C2910939485 @default.
• W2917730648 hasConceptScore W2917730648C54355233 @default.
• W2917730648 hasConceptScore W2917730648C71924100 @default.
• W2917730648 hasConceptScore W2917730648C86803240 @default.
• W2917730648 hasConceptScore W2917730648C99454951 @default.
• W2917730648 hasIssue "Suppl1" @default.
• W2917730648 hasLocation W29177306481 @default.
• W2917730648 hasLocation W29177306482 @default.
• W2917730648 hasOpenAccess W2917730648 @default.
• W2917730648 hasPrimaryLocation W29177306481 @default.

• next