Matches in SemOpenAlex for { <https://semopenalex.org/work/W2917765263> ?p ?o ?g. }
- W2917765263 endingPage "1432" @default.
- W2917765263 startingPage "1411" @default.
- W2917765263 abstract "The human gut contains trillions of symbiotic bacteria that play a key role in programming different aspects of host physiology in health and disease. Psychotropic medications act on the central nervous system (CNS) and are used in the treatment of various psychiatric disorders. There is increasing emphasis on the bidirectional interaction between drugs and the gut microbiome. An expanding body of evidence supports the notion that microbes can metabolise drugs and vice versa drugs can modify the gut microbiota composition. In this review, we will first give a comprehensive introduction about this bidirectional interaction, then we will take into consideration different classes of psychotropics including antipsychotics, antidepressants, antianxiety drugs, anticonvulsants/mood stabilisers, opioid analgesics, drugs of abuse, alcohol, nicotine and xanthines. The varying effects of these widely used medications on microorganisms are becoming apparent from in vivo and in vitro studies. This has important implications for the future of psychopharmacology pipelines that will routinely need to consider the host microbiome during drug discovery and development." @default.
- W2917765263 created "2019-03-02" @default.
- W2917765263 creator A5003021083 @default.
- W2917765263 creator A5009182799 @default.
- W2917765263 creator A5042008021 @default.
- W2917765263 creator A5084928512 @default.
- W2917765263 date "2019-02-26" @default.
- W2917765263 modified "2023-10-12" @default.
- W2917765263 title "Psychotropics and the Microbiome: a Chamber of Secrets…" @default.
- W2917765263 cites W123901329 @default.
- W2917765263 cites W132100242 @default.
- W2917765263 cites W1781074272 @default.
- W2917765263 cites W1940659245 @default.
- W2917765263 cites W1943350258 @default.
- W2917765263 cites W1945551477 @default.
- W2917765263 cites W1963903715 @default.
- W2917765263 cites W1966108143 @default.
- W2917765263 cites W1969614033 @default.
- W2917765263 cites W1975467646 @default.
- W2917765263 cites W1977429705 @default.
- W2917765263 cites W1977922285 @default.
- W2917765263 cites W1979102386 @default.
- W2917765263 cites W1979944856 @default.
- W2917765263 cites W1980260676 @default.
- W2917765263 cites W1982322762 @default.
- W2917765263 cites W1982537960 @default.
- W2917765263 cites W1983000423 @default.
- W2917765263 cites W1983086029 @default.
- W2917765263 cites W1984580264 @default.
- W2917765263 cites W1984969555 @default.
- W2917765263 cites W1985141199 @default.
- W2917765263 cites W1987184081 @default.
- W2917765263 cites W1994618906 @default.
- W2917765263 cites W1995278557 @default.
- W2917765263 cites W1998063413 @default.
- W2917765263 cites W1999971484 @default.
- W2917765263 cites W2000670099 @default.
- W2917765263 cites W2006155478 @default.
- W2917765263 cites W2013345346 @default.
- W2917765263 cites W2016990995 @default.
- W2917765263 cites W2019939591 @default.
- W2917765263 cites W2020539338 @default.
- W2917765263 cites W2021140068 @default.
- W2917765263 cites W2024187667 @default.
- W2917765263 cites W2025188153 @default.
- W2917765263 cites W2027968599 @default.
- W2917765263 cites W2028008812 @default.
- W2917765263 cites W2032756641 @default.
- W2917765263 cites W2034446643 @default.
- W2917765263 cites W2035289099 @default.
- W2917765263 cites W2038208465 @default.
- W2917765263 cites W2038991343 @default.
- W2917765263 cites W2040431746 @default.
- W2917765263 cites W2044238207 @default.
- W2917765263 cites W2048964217 @default.
- W2917765263 cites W2049832659 @default.
- W2917765263 cites W2050477554 @default.
- W2917765263 cites W2051066741 @default.
- W2917765263 cites W2051567523 @default.
- W2917765263 cites W2059128083 @default.
- W2917765263 cites W2059231279 @default.
- W2917765263 cites W2061598370 @default.
- W2917765263 cites W2063073547 @default.
- W2917765263 cites W2063856799 @default.
- W2917765263 cites W2069873068 @default.
- W2917765263 cites W2070879762 @default.
- W2917765263 cites W2072944905 @default.
- W2917765263 cites W2074908487 @default.
- W2917765263 cites W2075375216 @default.
- W2917765263 cites W2076427840 @default.
- W2917765263 cites W2077653833 @default.
- W2917765263 cites W2077942466 @default.
- W2917765263 cites W2080416827 @default.
- W2917765263 cites W2082704291 @default.
- W2917765263 cites W2084583367 @default.
- W2917765263 cites W2087292184 @default.
- W2917765263 cites W2089458297 @default.
- W2917765263 cites W2093431262 @default.
- W2917765263 cites W2095350647 @default.
- W2917765263 cites W2095576080 @default.
- W2917765263 cites W2097619155 @default.
- W2917765263 cites W2097648013 @default.
- W2917765263 cites W2100047947 @default.
- W2917765263 cites W2108424503 @default.
- W2917765263 cites W2111967195 @default.
- W2917765263 cites W2112214408 @default.
- W2917765263 cites W2113785871 @default.
- W2917765263 cites W2114259235 @default.
- W2917765263 cites W2114270323 @default.
- W2917765263 cites W2114605673 @default.
- W2917765263 cites W2123097904 @default.
- W2917765263 cites W2124557952 @default.
- W2917765263 cites W2129997370 @default.
- W2917765263 cites W2132351503 @default.
- W2917765263 cites W2133681569 @default.
- W2917765263 cites W2138648191 @default.
- W2917765263 cites W2139505909 @default.
- W2917765263 cites W2139884694 @default.