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• W2917962356 abstract "Background/aims: Studies have demonstrated that osteopontin (OPN) was associated with the severity and development of knee osteoarthritis (OA). Methods: The purpose of this case-control study was to investigate the association between OPN gene rs11730582 polymorphism and knee OA risk in a Chinese population. Genotyping was analyzed using standard PCR and restriction fragment length polymorphism (PCR-RFLP). Results: The present study found that C allele or CC genotype of OPN gene rs11730582 polymorphism was related to decreased risk for knee OA. Furthermore, positive associations were obtained amongst the females, and body mass index (BMI) < 25 kg/m2 groups. Conclusions: To sum up, the present study reveals that OPN gene rs11730582 polymorphism decreases the risk of knee OA in Chinese Han population." @default.
• W2917962356 created "2019-03-02" @default.
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• W2917962356 date "2019-02-01" @default.
• W2917962356 modified "2023-09-23" @default.
• W2917962356 title "<i>OPN</i> gene locus is associated with the risk of knee osteoarthritis: a case–control study" @default.
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• W2917962356 doi "https://doi.org/10.1042/bsr20182023" @default.
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