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- W2918261671 abstract "Background. Several large epidemiological studies have provided evidence of short-term adverse effects of particulate matter (PM) and gaseous pollutants on health. In Italy, an ongoing surveillance system (EpiAir) has already studied the effects on 10 cities in the 2001-2005 period. Aims. To enlarge the surveillance program on health effects of air pollution for cause-specific mortality updating it to the period 2006-2010, extending it to a larger number of cities (25) and studying for the first time in Italy the effects of PM below 2.5 ?m (PM2.5) in a consistent number of cities. Methods. Following standardized protocols, we collected daily mortality data for residents aged 35+ years for all natural, cardiac, cerebrovascular and respiratory causes. PM2.5 and nitrogen dioxide (NO2) were averaged for every city from selected monitoring stations. A two steps analysis was performed: a case-crossover analysis was conducted within each city, followed by a random-effects meta-analysis. Results. During the study period, we analyzed 422,723 deaths in 25 Italian cities for the NO2–mortality analysis, and 290,144 deaths from 13 cities for PM2.5. Statistically significant effects on natural mortality were found both for PM2.5 and NO2: percent increases of risk were 0.56% (95% confidence interval [CI]: 0.17%, 0.95%, lag 0-1) and1.14% (95% CI: 0.66%, 1.63%, lag 0-5), respectively. Delayed (lag 2-5) and prolonged (lag 0-5) effects of PM2.5 on cardiovascular mortality were also detected, with excess risks of 1.20% (95% CI: 0.34%, 2.06%) and 1.23% (95% CI: 0.19%, 2.27%) respectively. Conclusions. We found a large effect of PM2.5 on natural and cardiovascular mortality in 13 Italian cities. The large and prolonged effects of NO2 previously found (10 cities, 2001-2005) were confirmed on 25 cities, 2006-2010." @default.
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- W2918261671 date "2013-09-19" @default.
- W2918261671 modified "2023-10-16" @default.
- W2918261671 title "Short-term effects of PM2.5 and NO2 on mortality in 25 Italian cities: the EpiAir2 project" @default.
- W2918261671 doi "https://doi.org/10.1289/isee.2013.o-3-23-01" @default.
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