Matches in SemOpenAlex for { <https://semopenalex.org/work/W2918519897> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W2918519897 endingPage "2005" @default.
- W2918519897 startingPage "2005" @default.
- W2918519897 abstract "Purpose: Intra-arterial chemotherapy (IAC) has emerged as an effective treatment for retinoblastoma (RB) however, little information exists regarding its use in older patients (>5 years). In the present study, we evaluate the use of IAC (2008–2018) for RB in older patients and compare the outcomes to those in the prechemotherapy (<1994) and intravenous chemotherapy (IVC) (1994–2007) eras. Methods: A retrospective analysis of all patients older than 5 years treated with IAC for RB from 2008–2018. Comparisons were made to 26 active RB cases in older children treated in the prechemotherapy era and to 12 active RB cases treated in the IVC era. Results: There were 13 eyes with RB in 13 older patients treated in the IAC era. The median patient age was 6.8 years. Tumor response was achieved in all 13 eyes at a median interval of 1.1 months from first IAC. Globe salvage was achieved in eight eyes with five eyes requiring enucleation. At 14 months, median follow-up after IAC, there was no metastasis or death. Compared to the prechemotherapy era, those in the IAC era demonstrated significant reduction in need for enucleation (P < 0.001) and EBRT or enucleation (P < 0.001). Compared to the IVC era, there was significant reduction in need for EBRT (P = 0.02) and EBRT or enucleation (P = 0.03) and similar avoidance of metastasis (P > 0.99) and death (P > 0.99). Conclusion: Older patients with RB managed in the IAC era demonstrated reduced need for EBRT or enucleation compared to those managed in the IVC or prechemotherapy eras, with no instance of metastasis or death." @default.
- W2918519897 created "2019-03-11" @default.
- W2918519897 creator A5001760520 @default.
- W2918519897 creator A5026355189 @default.
- W2918519897 creator A5033179358 @default.
- W2918519897 creator A5061484429 @default.
- W2918519897 creator A5069640934 @default.
- W2918519897 date "2019-01-01" @default.
- W2918519897 modified "2023-09-30" @default.
- W2918519897 title "Management of retinoblastoma in older children (>5 years) using intra-arterial chemotherapy: Comparison of outcomes to prechemotherapy and intravenous chemotherapy eras" @default.
- W2918519897 cites W1844379777 @default.
- W2918519897 cites W1902808961 @default.
- W2918519897 cites W1980224204 @default.
- W2918519897 cites W1985610709 @default.
- W2918519897 cites W1995509840 @default.
- W2918519897 cites W2015249392 @default.
- W2918519897 cites W2024822082 @default.
- W2918519897 cites W2025712151 @default.
- W2918519897 cites W2048947239 @default.
- W2918519897 cites W2069655243 @default.
- W2918519897 cites W2086115121 @default.
- W2918519897 cites W2142480746 @default.
- W2918519897 cites W2254013392 @default.
- W2918519897 cites W2287928389 @default.
- W2918519897 cites W2322479806 @default.
- W2918519897 cites W2507899036 @default.
- W2918519897 cites W273601416 @default.
- W2918519897 cites W2755392039 @default.
- W2918519897 cites W2808809873 @default.
- W2918519897 cites W2922071674 @default.
- W2918519897 cites W608380506 @default.
- W2918519897 doi "https://doi.org/10.4103/ijo.ijo_642_19" @default.
- W2918519897 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6896522" @default.
- W2918519897 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31755439" @default.
- W2918519897 hasPublicationYear "2019" @default.
- W2918519897 type Work @default.
- W2918519897 sameAs 2918519897 @default.
- W2918519897 citedByCount "6" @default.
- W2918519897 countsByYear W29185198972019 @default.
- W2918519897 countsByYear W29185198972021 @default.
- W2918519897 countsByYear W29185198972022 @default.
- W2918519897 crossrefType "journal-article" @default.
- W2918519897 hasAuthorship W2918519897A5001760520 @default.
- W2918519897 hasAuthorship W2918519897A5026355189 @default.
- W2918519897 hasAuthorship W2918519897A5033179358 @default.
- W2918519897 hasAuthorship W2918519897A5061484429 @default.
- W2918519897 hasAuthorship W2918519897A5069640934 @default.
- W2918519897 hasBestOaLocation W29185198971 @default.
- W2918519897 hasConcept C104317684 @default.
- W2918519897 hasConcept C121608353 @default.
- W2918519897 hasConcept C126322002 @default.
- W2918519897 hasConcept C141071460 @default.
- W2918519897 hasConcept C167135981 @default.
- W2918519897 hasConcept C185592680 @default.
- W2918519897 hasConcept C188261085 @default.
- W2918519897 hasConcept C2776577112 @default.
- W2918519897 hasConcept C2776694085 @default.
- W2918519897 hasConcept C2779013556 @default.
- W2918519897 hasConcept C55493867 @default.
- W2918519897 hasConcept C71924100 @default.
- W2918519897 hasConceptScore W2918519897C104317684 @default.
- W2918519897 hasConceptScore W2918519897C121608353 @default.
- W2918519897 hasConceptScore W2918519897C126322002 @default.
- W2918519897 hasConceptScore W2918519897C141071460 @default.
- W2918519897 hasConceptScore W2918519897C167135981 @default.
- W2918519897 hasConceptScore W2918519897C185592680 @default.
- W2918519897 hasConceptScore W2918519897C188261085 @default.
- W2918519897 hasConceptScore W2918519897C2776577112 @default.
- W2918519897 hasConceptScore W2918519897C2776694085 @default.
- W2918519897 hasConceptScore W2918519897C2779013556 @default.
- W2918519897 hasConceptScore W2918519897C55493867 @default.
- W2918519897 hasConceptScore W2918519897C71924100 @default.
- W2918519897 hasIssue "12" @default.
- W2918519897 hasLocation W29185198971 @default.
- W2918519897 hasLocation W29185198972 @default.
- W2918519897 hasLocation W29185198973 @default.
- W2918519897 hasLocation W29185198974 @default.
- W2918519897 hasLocation W29185198975 @default.
- W2918519897 hasOpenAccess W2918519897 @default.
- W2918519897 hasPrimaryLocation W29185198971 @default.
- W2918519897 hasRelatedWork W2028662119 @default.
- W2918519897 hasRelatedWork W2047698445 @default.
- W2918519897 hasRelatedWork W2054697909 @default.
- W2918519897 hasRelatedWork W2059060788 @default.
- W2918519897 hasRelatedWork W2064219895 @default.
- W2918519897 hasRelatedWork W2171057357 @default.
- W2918519897 hasRelatedWork W2334205130 @default.
- W2918519897 hasRelatedWork W2487872961 @default.
- W2918519897 hasRelatedWork W2991475447 @default.
- W2918519897 hasRelatedWork W3032477005 @default.
- W2918519897 hasVolume "67" @default.
- W2918519897 isParatext "false" @default.
- W2918519897 isRetracted "false" @default.
- W2918519897 magId "2918519897" @default.
- W2918519897 workType "article" @default.