FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2918565981> ?p ?o ?g. }

• W2918565981 endingPage "741" @default.
• W2918565981 startingPage "734" @default.
• W2918565981 abstract "Objective The electrical properties of olfactory cells (OCs) are typically examined using animals such as newts, mice, and frogs, with few studies on human OCs. This study investigated the electrical properties of human cells from olfactory epithelium (hCOEs) obtained from subjects of olfactory epithelium showing no clinical symptoms during endoscopic sinus surgery. Methods hCOEs were isolated by collagenase treatment for whole-cell patch clamp recording. The identity of the cells was confirmed by immunohistochemistry with an antibody against olfactory maker protein. Under the voltage clamp with the whole-cell recording configuration, the voltage-gated currents of isolated hCOEs were recorded when the membrane potential was depolarized from a holding potential of −100 mV in a stepwise manner between −90 mV and + 40 mV. Results Only one of 14 hCOE samples expressed a transient inward current at the depolarizing voltage step that was activated by depolarization beyond −40 mV and reached a peak at −30 mV. Delayed and sustained outward currents (444 ± 106 pA at + 40 mV pulse; n = 20) were suppressed by tetraethyl ammonium (n = 3), which is consistent with the properties of newt OCs. Conclusions Most hCOEs did not exhibit the transient inward current observed in animal models. These findings provide insight into the physiological basis of the unique aspects of human olfactory signal transduction." @default.
• W2918565981 created "2019-03-11" @default.
• W2918565981 creator A5004420299 @default.
• W2918565981 creator A5031036106 @default.
• W2918565981 creator A5031577925 @default.
• W2918565981 creator A5047844727 @default.
• W2918565981 creator A5054823334 @default.
• W2918565981 creator A5068927073 @default.
• W2918565981 date "2019-10-01" @default.
• W2918565981 modified "2023-10-17" @default.
• W2918565981 title "Electrical properties of cells from human olfactory epithelium" @default.
• W2918565981 cites W1804958350 @default.
• W2918565981 cites W1905594901 @default.
• W2918565981 cites W1970706920 @default.
• W2918565981 cites W1971927522 @default.
• W2918565981 cites W1991862214 @default.
• W2918565981 cites W2002202194 @default.
• W2918565981 cites W2009667219 @default.
• W2918565981 cites W2011723731 @default.
• W2918565981 cites W2015207701 @default.
• W2918565981 cites W2017320072 @default.
• W2918565981 cites W2017625589 @default.
• W2918565981 cites W2017631205 @default.
• W2918565981 cites W2029235325 @default.
• W2918565981 cites W2031471871 @default.
• W2918565981 cites W2048091014 @default.
• W2918565981 cites W2048430622 @default.
• W2918565981 cites W2061428351 @default.
• W2918565981 cites W2090500868 @default.
• W2918565981 cites W2104720816 @default.
• W2918565981 cites W2110833648 @default.
• W2918565981 cites W2118044990 @default.
• W2918565981 cites W2126251398 @default.
• W2918565981 cites W2129102784 @default.
• W2918565981 cites W2151216132 @default.
• W2918565981 cites W2161994762 @default.
• W2918565981 cites W2165338498 @default.
• W2918565981 doi "https://doi.org/10.1016/j.anl.2019.01.006" @default.
• W2918565981 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30850172" @default.
• W2918565981 hasPublicationYear "2019" @default.
• W2918565981 type Work @default.
• W2918565981 sameAs 2918565981 @default.
• W2918565981 citedByCount "2" @default.
• W2918565981 countsByYear W29185659812023 @default.
• W2918565981 crossrefType "journal-article" @default.
• W2918565981 hasAuthorship W2918565981A5004420299 @default.
• W2918565981 hasAuthorship W2918565981A5031036106 @default.
• W2918565981 hasAuthorship W2918565981A5031577925 @default.
• W2918565981 hasAuthorship W2918565981A5047844727 @default.
• W2918565981 hasAuthorship W2918565981A5054823334 @default.
• W2918565981 hasAuthorship W2918565981A5068927073 @default.
• W2918565981 hasConcept C100837961 @default.
• W2918565981 hasConcept C105702510 @default.
• W2918565981 hasConcept C12554922 @default.
• W2918565981 hasConcept C126322002 @default.
• W2918565981 hasConcept C142724271 @default.
• W2918565981 hasConcept C147944092 @default.
• W2918565981 hasConcept C169760540 @default.
• W2918565981 hasConcept C181911157 @default.
• W2918565981 hasConcept C185263204 @default.
• W2918565981 hasConcept C201792869 @default.
• W2918565981 hasConcept C2780187430 @default.
• W2918565981 hasConcept C4141045 @default.
• W2918565981 hasConcept C529295009 @default.
• W2918565981 hasConcept C71924100 @default.
• W2918565981 hasConcept C86803240 @default.
• W2918565981 hasConceptScore W2918565981C100837961 @default.
• W2918565981 hasConceptScore W2918565981C105702510 @default.
• W2918565981 hasConceptScore W2918565981C12554922 @default.
• W2918565981 hasConceptScore W2918565981C126322002 @default.
• W2918565981 hasConceptScore W2918565981C142724271 @default.
• W2918565981 hasConceptScore W2918565981C147944092 @default.
• W2918565981 hasConceptScore W2918565981C169760540 @default.
• W2918565981 hasConceptScore W2918565981C181911157 @default.
• W2918565981 hasConceptScore W2918565981C185263204 @default.
• W2918565981 hasConceptScore W2918565981C201792869 @default.
• W2918565981 hasConceptScore W2918565981C2780187430 @default.
• W2918565981 hasConceptScore W2918565981C4141045 @default.
• W2918565981 hasConceptScore W2918565981C529295009 @default.
• W2918565981 hasConceptScore W2918565981C71924100 @default.
• W2918565981 hasConceptScore W2918565981C86803240 @default.
• W2918565981 hasFunder F4320334764 @default.
• W2918565981 hasIssue "5" @default.
• W2918565981 hasLocation W29185659811 @default.
• W2918565981 hasLocation W29185659812 @default.
• W2918565981 hasOpenAccess W2918565981 @default.
• W2918565981 hasPrimaryLocation W29185659811 @default.
• W2918565981 hasRelatedWork W1990054546 @default.
• W2918565981 hasRelatedWork W2013597739 @default.
• W2918565981 hasRelatedWork W2013640811 @default.
• W2918565981 hasRelatedWork W2055830121 @default.
• W2918565981 hasRelatedWork W2061630254 @default.
• W2918565981 hasRelatedWork W2073090149 @default.
• W2918565981 hasRelatedWork W2087539633 @default.
• W2918565981 hasRelatedWork W2106024132 @default.
• W2918565981 hasRelatedWork W2417181054 @default.
• W2918565981 hasRelatedWork W2417237198 @default.
• W2918565981 hasVolume "46" @default.

• next