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• W2918752434 startingPage "27" @default.
• W2918752434 abstract "In this review, we describe our experience in building a pilot-scale packed-bed solid-state fermentation (SSF) bioreactor, with provision for intermittent mixing, and the use of this bioreactor to produce pectinases and lipases by filamentous fungi. We show that, at pilot scale, special attention must be given to several aspects that are not usually problematic when one works with laboratory-scale SSF bioreactors. For example, it can be a challenge to produce large amounts of inoculum if the fungus does not sporulate well. Likewise, at larger scales, the air preparation system needs as much attention as the bioreactor itself. Sampling can also be problematic if one wishes to avoid disrupting the bed structure. In the fermentations carried out in the pilot bioreactor, when the substrate bed contained predominantly wheat bran, the bed shrank away from the walls, providing preferential flow paths for the air and necessitating agitation of the bed. These problems were avoided by using beds with approximately 50% of sugarcane bagasse. We also show how a mathematical model that describes heat and water transfer in the bed can be a useful tool in developing appropriate control schemes." @default.
• W2918752434 created "2019-03-11" @default.
• W2918752434 creator A5007621417 @default.
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• W2918752434 date "2019-01-01" @default.
• W2918752434 modified "2023-10-03" @default.
• W2918752434 title "Design and Operation of a Pilot-Scale Packed-Bed Bioreactor for the Production of Enzymes by Solid-State Fermentation" @default.
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• W2918752434 doi "https://doi.org/10.1007/10_2019_90" @default.
• W2918752434 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30828754" @default.
• W2918752434 hasPublicationYear "2019" @default.
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