FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2918920715> ?p ?o ?g. }

• W2918920715 endingPage "95" @default.
• W2918920715 startingPage "95" @default.
• W2918920715 abstract "Locally advanced non-small cell lung cancer (NSCLC) may exhibit significant tumor growth before the initiation of definitive chemoradiation therapy (CRT). We thus investigated the prognostic value of pretreatment tumor growth rate as measured by specific growth rate (SGR).We conducted a retrospective review of 42 patients with locally advanced NSCLC treated with definitive concurrent CRT. For each patient, we contoured the primary gross tumor volume (GTV) on the pretreatment diagnostic chest computed tomography (CT) scan and the radiation therapy (RT) planning CT scan. We then calculated SGR based on the primary GTV from each scan and the time interval between scans. We used log-rank tests and univariate Cox regression models to quantify differences in progression-free survival (PFS), overall survival (OS) and recurrence based on SGR.We divided patients into two groups for analysis: those with an SGR greater than or equal to the upper tercile value of 0.94%/day (high SGR) and those with SGR less than 0.94%/day (low SGR). Patients with high SGRs versus low SGRs experienced inferior PFS (median, 5.6 vs. 13.6 months, P=0.016), without a significant difference in OS. The inferior PFS in the high SGR group persisted on multivariate analysis [adjusted hazard ratio (HR) 2.37, 95% confidence interval (CI): 1.07-5.25, P=0.034]. The risk of distant recurrence was higher in the high SGR group (HR 2.62, 95% CI: 1.08-6.38, P=0.033), but there was no difference in the risk of locoregional recurrence between groups.Pretreatment SGR was associated with inferior PFS and distant control among patients with locally advanced NSCLC treated with concurrent CRT. Further studies in larger populations may aid in elucidating optimal SGR cut-off points for risk stratification." @default.
• W2918920715 created "2019-03-11" @default.
• W2918920715 creator A5000667041 @default.
• W2918920715 creator A5005298316 @default.
• W2918920715 creator A5006355538 @default.
• W2918920715 creator A5046406616 @default.
• W2918920715 creator A5048331793 @default.
• W2918920715 creator A5054371540 @default.
• W2918920715 creator A5067536094 @default.
• W2918920715 creator A5069565044 @default.
• W2918920715 creator A5069684066 @default.
• W2918920715 creator A5082312064 @default.
• W2918920715 creator A5084574866 @default.
• W2918920715 creator A5087198417 @default.
• W2918920715 creator A5090002307 @default.
• W2918920715 date "2019-03-01" @default.
• W2918920715 modified "2023-10-15" @default.
• W2918920715 title "Clinical significance of pretreatment tumor growth rate for locally advanced non-small cell lung cancer" @default.
• W2918920715 cites W1968899146 @default.
• W2918920715 cites W1977155686 @default.
• W2918920715 cites W1985285668 @default.
• W2918920715 cites W2000009782 @default.
• W2918920715 cites W2045388014 @default.
• W2918920715 cites W2063247340 @default.
• W2918920715 cites W2067903148 @default.
• W2918920715 cites W2135842710 @default.
• W2918920715 cites W2149569497 @default.
• W2918920715 cites W2152939220 @default.
• W2918920715 cites W2167968937 @default.
• W2918920715 cites W2252723759 @default.
• W2918920715 cites W2608413653 @default.
• W2918920715 cites W2747425692 @default.
• W2918920715 cites W2893824814 @default.
• W2918920715 doi "https://doi.org/10.21037/atm.2019.02.14" @default.
• W2918920715 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6462644" @default.
• W2918920715 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31019945" @default.
• W2918920715 hasPublicationYear "2019" @default.
• W2918920715 type Work @default.
• W2918920715 sameAs 2918920715 @default.
• W2918920715 citedByCount "3" @default.
• W2918920715 countsByYear W29189207152019 @default.
• W2918920715 countsByYear W29189207152021 @default.
• W2918920715 countsByYear W29189207152023 @default.
• W2918920715 crossrefType "journal-article" @default.
• W2918920715 hasAuthorship W2918920715A5000667041 @default.
• W2918920715 hasAuthorship W2918920715A5005298316 @default.
• W2918920715 hasAuthorship W2918920715A5006355538 @default.
• W2918920715 hasAuthorship W2918920715A5046406616 @default.
• W2918920715 hasAuthorship W2918920715A5048331793 @default.
• W2918920715 hasAuthorship W2918920715A5054371540 @default.
• W2918920715 hasAuthorship W2918920715A5067536094 @default.
• W2918920715 hasAuthorship W2918920715A5069565044 @default.
• W2918920715 hasAuthorship W2918920715A5069684066 @default.
• W2918920715 hasAuthorship W2918920715A5082312064 @default.
• W2918920715 hasAuthorship W2918920715A5084574866 @default.
• W2918920715 hasAuthorship W2918920715A5087198417 @default.
• W2918920715 hasAuthorship W2918920715A5090002307 @default.
• W2918920715 hasBestOaLocation W29189207151 @default.
• W2918920715 hasConcept C121608353 @default.
• W2918920715 hasConcept C126322002 @default.
• W2918920715 hasConcept C126838900 @default.
• W2918920715 hasConcept C143998085 @default.
• W2918920715 hasConcept C144301174 @default.
• W2918920715 hasConcept C167135981 @default.
• W2918920715 hasConcept C207103383 @default.
• W2918920715 hasConcept C2776256026 @default.
• W2918920715 hasConcept C2779013556 @default.
• W2918920715 hasConcept C2780283643 @default.
• W2918920715 hasConcept C2989005 @default.
• W2918920715 hasConcept C38180746 @default.
• W2918920715 hasConcept C44249647 @default.
• W2918920715 hasConcept C50382708 @default.
• W2918920715 hasConcept C509974204 @default.
• W2918920715 hasConcept C71924100 @default.
• W2918920715 hasConceptScore W2918920715C121608353 @default.
• W2918920715 hasConceptScore W2918920715C126322002 @default.
• W2918920715 hasConceptScore W2918920715C126838900 @default.
• W2918920715 hasConceptScore W2918920715C143998085 @default.
• W2918920715 hasConceptScore W2918920715C144301174 @default.
• W2918920715 hasConceptScore W2918920715C167135981 @default.
• W2918920715 hasConceptScore W2918920715C207103383 @default.
• W2918920715 hasConceptScore W2918920715C2776256026 @default.
• W2918920715 hasConceptScore W2918920715C2779013556 @default.
• W2918920715 hasConceptScore W2918920715C2780283643 @default.
• W2918920715 hasConceptScore W2918920715C2989005 @default.
• W2918920715 hasConceptScore W2918920715C38180746 @default.
• W2918920715 hasConceptScore W2918920715C44249647 @default.
• W2918920715 hasConceptScore W2918920715C50382708 @default.
• W2918920715 hasConceptScore W2918920715C509974204 @default.
• W2918920715 hasConceptScore W2918920715C71924100 @default.
• W2918920715 hasIssue "5" @default.
• W2918920715 hasLocation W29189207151 @default.
• W2918920715 hasLocation W29189207152 @default.
• W2918920715 hasLocation W29189207153 @default.
• W2918920715 hasLocation W29189207154 @default.
• W2918920715 hasOpenAccess W2918920715 @default.
• W2918920715 hasPrimaryLocation W29189207151 @default.
• W2918920715 hasRelatedWork W1975698825 @default.

• next