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- W2919009825 abstract "Introduction: Accumulating data from recent studies has altered the gold standard of care for diabetes treatment. In patients with type 2 diabetes (T2D) and established cardiovascular disease (CVD) or those at high risk for CVD, subsequently to lifestyle changes and metformin therapy, the administration of an SGLT-2 inhibitor with established benefits for cardiovascular outcome (CVOT) should be considered.Areas covered: Tofogliflozin is the most selective SGLT-2 inhibitor and has been approved for the treatment of T2D in Japan. This review summarizes the available data on Tofogliflozin as compared to other SGLT-2 inhibitors, and primarily the three SGLT-2 inhibitors with published CVOT: Empagliflozin, Canagliflozin and Dapagliflozin.Expert opinion: Tofogliflozin’s higher selectivity profile increases the positive effects on cardiovascular (CV) outcomes and death and reduces side effects. However, the clinical data on Tofogliflozin from both clinical and real-world studies remain sparse and much less abundant than the other main 3 SGLT-2 inhibitors, thus calling for caution and underscoring the need for further research." @default.
- W2919009825 created "2019-03-11" @default.
- W2919009825 creator A5031159026 @default.
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- W2919009825 date "2019-03-05" @default.
- W2919009825 modified "2023-09-23" @default.
- W2919009825 title "An evaluation of the efficacy and safety of Tofogliflozin for the treatment of type II diabetes" @default.
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- W2919009825 doi "https://doi.org/10.1080/14656566.2019.1583210" @default.
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