FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2919779855> ?p ?o ?g. }

• W2919779855 endingPage "e13251" @default.
• W2919779855 startingPage "e13251" @default.
• W2919779855 abstract "The aim of this study was to elucidate the reproductive toxicity of the coadministration of diltiazem and cyclosporine A or tacrolimus. Testicular development, semen quality, sex hormones and testicular tissues were assessed in unilateral nephrectomised (UN) rats, including the control group, UN group, UN+CsA group, UN+FK506 group, UN+Rapa group, UN+CsA+Dil group and UN+FK506+Dil group. The testicular coefficient, the sperm number and the sperm motility were lower in the treatment groups (except UN+FK506) than in the control and UN groups (all p < 0.05). The lowest sperm number and motility were identified in the UN+CsA+Dil group, followed by the UN+CsA group. The proportion of abnormal sperm was higher in the UN+CsA and UN+CsA+Dil groups than in the control and UN groups, respectively (p < 0.05). The plasma concentrations of sex hormones were changed in the treatment groups. Dil can increase the blood concentrations of CsA and FK506 (◇p < 0.05, ◆p < 0.05). Therapeutic doses of these agents induced morphological changes in the testicular tissue and ultrastructural changes in the testosterone, mesenchymal cells and supporting cells. Our present study suggests that Dil can increase the testicular toxicity of CNIs (calcineurin inhibitors, including CsA and FK506) by enhancing the plasma concentrations of CNIs." @default.
• W2919779855 created "2019-03-11" @default.
• W2919779855 creator A5008797609 @default.
• W2919779855 creator A5011233723 @default.
• W2919779855 creator A5033571036 @default.
• W2919779855 creator A5054195152 @default.
• W2919779855 creator A5058497975 @default.
• W2919779855 creator A5061395340 @default.
• W2919779855 creator A5062538172 @default.
• W2919779855 creator A5066180348 @default.
• W2919779855 creator A5078627573 @default.
• W2919779855 creator A5090706844 @default.
• W2919779855 date "2019-02-28" @default.
• W2919779855 modified "2023-10-18" @default.
• W2919779855 title "Diltiazem aggravates testicular function impairment induced by cyclosporine A or tacrolimus in unilateral nephrectomised rats" @default.
• W2919779855 cites W1607800120 @default.
• W2919779855 cites W1957547329 @default.
• W2919779855 cites W1968495504 @default.
• W2919779855 cites W1969336978 @default.
• W2919779855 cites W1982500749 @default.
• W2919779855 cites W1994351795 @default.
• W2919779855 cites W1996224033 @default.
• W2919779855 cites W2000923578 @default.
• W2919779855 cites W2003886322 @default.
• W2919779855 cites W2017956661 @default.
• W2919779855 cites W2023452100 @default.
• W2919779855 cites W2029787393 @default.
• W2919779855 cites W2034702552 @default.
• W2919779855 cites W2039755588 @default.
• W2919779855 cites W2055048863 @default.
• W2919779855 cites W2059801270 @default.
• W2919779855 cites W2064818979 @default.
• W2919779855 cites W2072786219 @default.
• W2919779855 cites W2084592920 @default.
• W2919779855 cites W2102129490 @default.
• W2919779855 cites W2109019161 @default.
• W2919779855 cites W2117230863 @default.
• W2919779855 cites W2126785859 @default.
• W2919779855 cites W2137896826 @default.
• W2919779855 cites W2150069482 @default.
• W2919779855 cites W2246837230 @default.
• W2919779855 cites W2324000686 @default.
• W2919779855 cites W2410831871 @default.
• W2919779855 cites W2466974137 @default.
• W2919779855 cites W2516177238 @default.
• W2919779855 cites W2615904154 @default.
• W2919779855 cites W2618676493 @default.
• W2919779855 cites W1968941639 @default.
• W2919779855 doi "https://doi.org/10.1111/and.13251" @default.
• W2919779855 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30821033" @default.
• W2919779855 hasPublicationYear "2019" @default.
• W2919779855 type Work @default.
• W2919779855 sameAs 2919779855 @default.
• W2919779855 citedByCount "1" @default.
• W2919779855 countsByYear W29197798552020 @default.
• W2919779855 crossrefType "journal-article" @default.
• W2919779855 hasAuthorship W2919779855A5008797609 @default.
• W2919779855 hasAuthorship W2919779855A5011233723 @default.
• W2919779855 hasAuthorship W2919779855A5033571036 @default.
• W2919779855 hasAuthorship W2919779855A5054195152 @default.
• W2919779855 hasAuthorship W2919779855A5058497975 @default.
• W2919779855 hasAuthorship W2919779855A5061395340 @default.
• W2919779855 hasAuthorship W2919779855A5062538172 @default.
• W2919779855 hasAuthorship W2919779855A5066180348 @default.
• W2919779855 hasAuthorship W2919779855A5078627573 @default.
• W2919779855 hasAuthorship W2919779855A5090706844 @default.
• W2919779855 hasBestOaLocation W29197798551 @default.
• W2919779855 hasConcept C126322002 @default.
• W2919779855 hasConcept C128057223 @default.
• W2919779855 hasConcept C134018914 @default.
• W2919779855 hasConcept C16685009 @default.
• W2919779855 hasConcept C2777632594 @default.
• W2919779855 hasConcept C2778093475 @default.
• W2919779855 hasConcept C2779066085 @default.
• W2919779855 hasConcept C2779279991 @default.
• W2919779855 hasConcept C2781087480 @default.
• W2919779855 hasConcept C2909675724 @default.
• W2919779855 hasConcept C2911091166 @default.
• W2919779855 hasConcept C29730261 @default.
• W2919779855 hasConcept C54355233 @default.
• W2919779855 hasConcept C58207958 @default.
• W2919779855 hasConcept C71315377 @default.
• W2919779855 hasConcept C71924100 @default.
• W2919779855 hasConcept C86803240 @default.
• W2919779855 hasConceptScore W2919779855C126322002 @default.
• W2919779855 hasConceptScore W2919779855C128057223 @default.
• W2919779855 hasConceptScore W2919779855C134018914 @default.
• W2919779855 hasConceptScore W2919779855C16685009 @default.
• W2919779855 hasConceptScore W2919779855C2777632594 @default.
• W2919779855 hasConceptScore W2919779855C2778093475 @default.
• W2919779855 hasConceptScore W2919779855C2779066085 @default.
• W2919779855 hasConceptScore W2919779855C2779279991 @default.
• W2919779855 hasConceptScore W2919779855C2781087480 @default.
• W2919779855 hasConceptScore W2919779855C2909675724 @default.
• W2919779855 hasConceptScore W2919779855C2911091166 @default.
• W2919779855 hasConceptScore W2919779855C29730261 @default.
• W2919779855 hasConceptScore W2919779855C54355233 @default.
• W2919779855 hasConceptScore W2919779855C58207958 @default.

• next