FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2920031833> ?p ?o ?g. }

• W2920031833 abstract "Introduction Richter’s transformation (RT) refers to the development of an aggressive lymphoma in patients with chronic lymphocytic leukaemia (CLL) or small lymphocytic lymphoma. Studies have shown that 2–10% of patients with CLL develop RT including diffuse large B-cell lymphoma (DLBCL) and less common Hodgkin lymphoma (HL). This study aims to assess the risk factors for RT of CLL in a nationwide cohort. Additionally, we want to examine prognostic factors in patients with RT. These findings may guide management of treated as well as untreated patients with CLL in the risk of RT. Methods Clinical data for patients diagnosed with CLL between 2008 and 2016 will be retrieved from the Danish National CLL registry (DCLLR). Using the Danish unique person identification number, clinical data will be merged with histologically verified DLBCL and/or HL diagnoses retrieved from the Danish National Pathology Data Bank. This will ensure complete follow-up for all patients. The DCLLR includes data from more than 4000 patients with CLL ensuring a median follow-up of 3 years. With the reported incidences (2-10%) of RT, we expect to identify 80–200 CLL patients with RT enabling analysis of overall survival following RT. From time of CLL diagnosis, estimates of cumulative incidence of RT will be calculated using the Aalen-Johansen estimator. From time of RT diagnosis, survival analysis will be performed by Kaplan-Meier method. Cox proportional hazards models will be used for multivariable survival analysis. Ethics and dissemination Approvals for data collection and analysis was obtained from the Danish Data Protection Agency and the Danish Health Authorities. All data will be managed confidentially according to guidelines and legislation. The dissemination will include a publication of scientific papers and/or presentations of the study findings at international conferences." @default.
• W2920031833 created "2019-03-11" @default.
• W2920031833 creator A5011876375 @default.
• W2920031833 creator A5018408489 @default.
• W2920031833 creator A5021929721 @default.
• W2920031833 creator A5023096734 @default.
• W2920031833 creator A5028769876 @default.
• W2920031833 creator A5030819112 @default.
• W2920031833 creator A5057884204 @default.
• W2920031833 date "2019-03-01" @default.
• W2920031833 modified "2023-09-25" @default.
• W2920031833 title "Risk factors associated with Richter’s transformation in patients with chronic lymphocytic leukaemia: protocol for a retrospective population-based cohort study" @default.
• W2920031833 cites W1555998680 @default.
• W2920031833 cites W1605184956 @default.
• W2920031833 cites W1992857313 @default.
• W2920031833 cites W2008650271 @default.
• W2920031833 cites W2014119870 @default.
• W2920031833 cites W2054943699 @default.
• W2920031833 cites W2058370462 @default.
• W2920031833 cites W2060489569 @default.
• W2920031833 cites W2061128187 @default.
• W2920031833 cites W2102420102 @default.
• W2920031833 cites W2122285534 @default.
• W2920031833 cites W2130081091 @default.
• W2920031833 cites W2133545780 @default.
• W2920031833 cites W2168905545 @default.
• W2920031833 cites W2219591537 @default.
• W2920031833 cites W2253032999 @default.
• W2920031833 cites W2283026262 @default.
• W2920031833 cites W2544982242 @default.
• W2920031833 cites W2566053885 @default.
• W2920031833 cites W2744781811 @default.
• W2920031833 doi "https://doi.org/10.1136/bmjopen-2018-023566" @default.
• W2920031833 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6443055" @default.
• W2920031833 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30833314" @default.
• W2920031833 hasPublicationYear "2019" @default.
• W2920031833 type Work @default.
• W2920031833 sameAs 2920031833 @default.
• W2920031833 citedByCount "5" @default.
• W2920031833 countsByYear W29200318332020 @default.
• W2920031833 countsByYear W29200318332021 @default.
• W2920031833 crossrefType "journal-article" @default.
• W2920031833 hasAuthorship W2920031833A5011876375 @default.
• W2920031833 hasAuthorship W2920031833A5018408489 @default.
• W2920031833 hasAuthorship W2920031833A5021929721 @default.
• W2920031833 hasAuthorship W2920031833A5023096734 @default.
• W2920031833 hasAuthorship W2920031833A5028769876 @default.
• W2920031833 hasAuthorship W2920031833A5030819112 @default.
• W2920031833 hasAuthorship W2920031833A5057884204 @default.
• W2920031833 hasBestOaLocation W29200318331 @default.
• W2920031833 hasConcept C107130276 @default.
• W2920031833 hasConcept C120665830 @default.
• W2920031833 hasConcept C121332964 @default.
• W2920031833 hasConcept C126322002 @default.
• W2920031833 hasConcept C138885662 @default.
• W2920031833 hasConcept C143998085 @default.
• W2920031833 hasConcept C164622146 @default.
• W2920031833 hasConcept C2777938653 @default.
• W2920031833 hasConcept C2778461978 @default.
• W2920031833 hasConcept C2778559949 @default.
• W2920031833 hasConcept C2779338263 @default.
• W2920031833 hasConcept C2780653079 @default.
• W2920031833 hasConcept C2781214270 @default.
• W2920031833 hasConcept C2908647359 @default.
• W2920031833 hasConcept C41895202 @default.
• W2920031833 hasConcept C50382708 @default.
• W2920031833 hasConcept C61511704 @default.
• W2920031833 hasConcept C71924100 @default.
• W2920031833 hasConcept C72563966 @default.
• W2920031833 hasConcept C88879693 @default.
• W2920031833 hasConcept C99454951 @default.
• W2920031833 hasConceptScore W2920031833C107130276 @default.
• W2920031833 hasConceptScore W2920031833C120665830 @default.
• W2920031833 hasConceptScore W2920031833C121332964 @default.
• W2920031833 hasConceptScore W2920031833C126322002 @default.
• W2920031833 hasConceptScore W2920031833C138885662 @default.
• W2920031833 hasConceptScore W2920031833C143998085 @default.
• W2920031833 hasConceptScore W2920031833C164622146 @default.
• W2920031833 hasConceptScore W2920031833C2777938653 @default.
• W2920031833 hasConceptScore W2920031833C2778461978 @default.
• W2920031833 hasConceptScore W2920031833C2778559949 @default.
• W2920031833 hasConceptScore W2920031833C2779338263 @default.
• W2920031833 hasConceptScore W2920031833C2780653079 @default.
• W2920031833 hasConceptScore W2920031833C2781214270 @default.
• W2920031833 hasConceptScore W2920031833C2908647359 @default.
• W2920031833 hasConceptScore W2920031833C41895202 @default.
• W2920031833 hasConceptScore W2920031833C50382708 @default.
• W2920031833 hasConceptScore W2920031833C61511704 @default.
• W2920031833 hasConceptScore W2920031833C71924100 @default.
• W2920031833 hasConceptScore W2920031833C72563966 @default.
• W2920031833 hasConceptScore W2920031833C88879693 @default.
• W2920031833 hasConceptScore W2920031833C99454951 @default.
• W2920031833 hasLocation W29200318331 @default.
• W2920031833 hasLocation W29200318332 @default.
• W2920031833 hasLocation W29200318333 @default.
• W2920031833 hasLocation W29200318334 @default.
• W2920031833 hasLocation W29200318335 @default.
• W2920031833 hasOpenAccess W2920031833 @default.
• W2920031833 hasPrimaryLocation W29200318331 @default.
• W2920031833 hasRelatedWork W1969612927 @default.

• next