FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2920192166> ?p ?o ?g. }

• W2920192166 endingPage "755" @default.
• W2920192166 startingPage "745" @default.
• W2920192166 abstract "Abstract Editor’s Perspective What We Already Know about This Topic The nociception level index (Medasense Biometrics Ltd., Ramat Gan, Israel), is a reliable measure of moderate to intense noxious stimulation during anesthesia and surgery What This Article Tells Us That Is New In a randomized trial in patients having major abdominal surgery, compared to standard practice, nociception level-guided analgesia resulted in 30% less intraoperative remifentanil consumption Background The multidimensional index of nociception, the nociception level, outperforms blood pressure and heart rate in detection of nociceptive events during anesthesia. We hypothesized that nociception level–guided analgesia reduces opioid consumption and suboptimal anesthesia events such as low blood pressure and use of vasoactive medication. Methods In this single-blinded randomized study, 80 American Society of Anesthesiologists class I–III adult patients of either sex, scheduled for major abdominal procedures under remifentanil/propofol anesthesia by target-controlled infusion, were included. During the procedure nociception level, noninvasive blood pressure, and heart rate were monitored. Patients were randomized to receive standard clinical care or nociception level–guided analgesia. In the nociception level–guided group, remifentanil concentration was reduced when index values were less than 10 or increased when values were above 25 for at least 1 min, in steps of 0.5 to 1.0 ng/ml. Propofol was titrated to bispectral index values between 45 and 55. The primary outcomes of the study were remifentanil and propofol consumption and inadequate anesthesia events. Results Compared with standard care, remifentanil administration was reduced in nociception level–guided patients from (mean ± SD) 0.119 ± 0.033 to 0.086 ± 0.032 μg · kg-1 · min-1 (mean difference, 0.039 μg · kg-1 · min-1; 95% CI, 0.025–0.052 μg · kg-1 · min-1; P &lt; 0.001). Among nociception level–guided patients, 2 of 40 (5%) experienced a hypotensive event (mean arterial pressure values less than 55 mm Hg) versus 11 of 40 (28%) patients in the control group (relative risk, 0.271; 95% CI, 0.08–0.77; P = 0.006). In the nociception level–guided group, 16 of 40 (40%) patients received vasoactive medication versus 25 of 40 (63%) patients in the standard care group (relative risk, 0.64; 95% CI, 0.40–0.99; P = 0.044). Conclusions Nociception level-guided analgesia during major abdominal surgery resulted in 30% less remifentanil consumption." @default.
• W2920192166 created "2019-03-11" @default.
• W2920192166 creator A5041229784 @default.
• W2920192166 creator A5042412836 @default.
• W2920192166 creator A5052805595 @default.
• W2920192166 creator A5064619482 @default.
• W2920192166 creator A5072862006 @default.
• W2920192166 creator A5077603374 @default.
• W2920192166 creator A5078916012 @default.
• W2920192166 creator A5085079099 @default.
• W2920192166 creator A5086401956 @default.
• W2920192166 date "2019-05-01" @default.
• W2920192166 modified "2023-10-15" @default.
• W2920192166 title "Nociception-guided <i>versus</i> Standard Care during Remifentanil–Propofol Anesthesia" @default.
• W2920192166 cites W1582404770 @default.
• W2920192166 cites W1990836414 @default.
• W2920192166 cites W2017221863 @default.
• W2920192166 cites W2023919652 @default.
• W2920192166 cites W2047780340 @default.
• W2920192166 cites W2071317972 @default.
• W2920192166 cites W2099010807 @default.
• W2920192166 cites W2120606817 @default.
• W2920192166 cites W2126155630 @default.
• W2920192166 cites W2137546126 @default.
• W2920192166 cites W2138815770 @default.
• W2920192166 cites W2142823558 @default.
• W2920192166 cites W2158297165 @default.
• W2920192166 cites W2376783461 @default.
• W2920192166 cites W2488700677 @default.
• W2920192166 cites W2623298289 @default.
• W2920192166 cites W2738312094 @default.
• W2920192166 cites W2795355519 @default.
• W2920192166 doi "https://doi.org/10.1097/aln.0000000000002634" @default.
• W2920192166 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30829658" @default.
• W2920192166 hasPublicationYear "2019" @default.
• W2920192166 type Work @default.
• W2920192166 sameAs 2920192166 @default.
• W2920192166 citedByCount "55" @default.
• W2920192166 countsByYear W29201921662019 @default.
• W2920192166 countsByYear W29201921662020 @default.
• W2920192166 countsByYear W29201921662021 @default.
• W2920192166 countsByYear W29201921662022 @default.
• W2920192166 countsByYear W29201921662023 @default.
• W2920192166 crossrefType "journal-article" @default.
• W2920192166 hasAuthorship W2920192166A5041229784 @default.
• W2920192166 hasAuthorship W2920192166A5042412836 @default.
• W2920192166 hasAuthorship W2920192166A5052805595 @default.
• W2920192166 hasAuthorship W2920192166A5064619482 @default.
• W2920192166 hasAuthorship W2920192166A5072862006 @default.
• W2920192166 hasAuthorship W2920192166A5077603374 @default.
• W2920192166 hasAuthorship W2920192166A5078916012 @default.
• W2920192166 hasAuthorship W2920192166A5085079099 @default.
• W2920192166 hasAuthorship W2920192166A5086401956 @default.
• W2920192166 hasBestOaLocation W29201921661 @default.
• W2920192166 hasConcept C126322002 @default.
• W2920192166 hasConcept C141071460 @default.
• W2920192166 hasConcept C15490471 @default.
• W2920192166 hasConcept C168563851 @default.
• W2920192166 hasConcept C170493617 @default.
• W2920192166 hasConcept C2776277131 @default.
• W2920192166 hasConcept C2777953023 @default.
• W2920192166 hasConcept C2778891214 @default.
• W2920192166 hasConcept C2781097354 @default.
• W2920192166 hasConcept C42219234 @default.
• W2920192166 hasConcept C71924100 @default.
• W2920192166 hasConcept C84393581 @default.
• W2920192166 hasConceptScore W2920192166C126322002 @default.
• W2920192166 hasConceptScore W2920192166C141071460 @default.
• W2920192166 hasConceptScore W2920192166C15490471 @default.
• W2920192166 hasConceptScore W2920192166C168563851 @default.
• W2920192166 hasConceptScore W2920192166C170493617 @default.
• W2920192166 hasConceptScore W2920192166C2776277131 @default.
• W2920192166 hasConceptScore W2920192166C2777953023 @default.
• W2920192166 hasConceptScore W2920192166C2778891214 @default.
• W2920192166 hasConceptScore W2920192166C2781097354 @default.
• W2920192166 hasConceptScore W2920192166C42219234 @default.
• W2920192166 hasConceptScore W2920192166C71924100 @default.
• W2920192166 hasConceptScore W2920192166C84393581 @default.
• W2920192166 hasIssue "5" @default.
• W2920192166 hasLocation W29201921661 @default.
• W2920192166 hasLocation W29201921662 @default.
• W2920192166 hasLocation W29201921663 @default.
• W2920192166 hasOpenAccess W2920192166 @default.
• W2920192166 hasPrimaryLocation W29201921661 @default.
• W2920192166 hasRelatedWork W1964497275 @default.
• W2920192166 hasRelatedWork W1996356226 @default.
• W2920192166 hasRelatedWork W2005998605 @default.
• W2920192166 hasRelatedWork W2038661164 @default.
• W2920192166 hasRelatedWork W2120027149 @default.
• W2920192166 hasRelatedWork W2324428236 @default.
• W2920192166 hasRelatedWork W2393748027 @default.
• W2920192166 hasRelatedWork W2513475169 @default.
• W2920192166 hasRelatedWork W2613033866 @default.
• W2920192166 hasRelatedWork W3030904938 @default.
• W2920192166 hasVolume "130" @default.
• W2920192166 isParatext "false" @default.
• W2920192166 isRetracted "false" @default.
• W2920192166 magId "2920192166" @default.

• next