FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2920200983> ?p ?o ?g. }

• W2920200983 abstract "Von Hippel-Lindau (VHL) disease is a genetic syndrome that involves the development of tumors in numerous organs. The kidney is one of the most frequently affected organs, and patients with VHL and renal tumors require repeated nephrectomy. The present study aimed to further determine the clinicopathological characteristics of patients with VHL-associated renal cell carcinoma (RCC), which may allow more rational clinical treatment decisions. This study included 27 patients with VHL who underwent radical or partial nephrectomy at the Peking University First Hospital between January 2010 and April 2018. The clinicopathological characteristics and prognosis of the patients were retrospectively reviewed. The expression of RCC-associated molecular markers was evaluated by immunohistochemistry. The mean size of the renal tumors was 4.3±2.0 cm (range 1.3-9.5 cm). The pathological type in 26 cases (96.3%) was clear cell RCC (CCRCC), whereas only one patient was diagnosed with CCRCC and clear cell papillary RCC. Renal cysts with a clear cell lining were observed, and RCC cell clusters were scattered in renal cyst cavities. Among the 27 patients, 21 (77.8%) were diagnosed with stage IA/T1N0M0, according to Tumor-Node-Metastasis staging, and 16 (59.3%) had grade 1 tumors. The mean postoperative follow-up duration was 39.0±24.0 months (range, 1.7-96.5 months). No metastasis or VHL-associated mortality was observed. VHL-associated RCC is a relatively low-risk disease, and a tumor size of 4 cm was determined as a threshold for nephron-sparing surgery. In addition, to prevent tumor cell dispersion, renal cysts should be carefully treated. A comprehensive understanding of the clinicopathological characteristics and underlying mechanisms of RCC associated with VHL syndrome may improve patient prognosis." @default.
• W2920200983 created "2019-03-11" @default.
• W2920200983 creator A5014028086 @default.
• W2920200983 creator A5027904854 @default.
• W2920200983 creator A5028066952 @default.
• W2920200983 creator A5042665218 @default.
• W2920200983 creator A5042791790 @default.
• W2920200983 creator A5054418515 @default.
• W2920200983 creator A5058554971 @default.
• W2920200983 creator A5076246947 @default.
• W2920200983 date "2019-03-01" @default.
• W2920200983 modified "2023-09-26" @default.
• W2920200983 title "Distinctive clinicopathological features of Von�Hippel‑Lindau‑associated hereditary renal cell carcinoma: A single‑institution study" @default.
• W2920200983 cites W1968472532 @default.
• W2920200983 cites W1990588975 @default.
• W2920200983 cites W2005230197 @default.
• W2920200983 cites W2011499154 @default.
• W2920200983 cites W2030376875 @default.
• W2920200983 cites W2037966103 @default.
• W2920200983 cites W2045891052 @default.
• W2920200983 cites W2052271345 @default.
• W2920200983 cites W2058862357 @default.
• W2920200983 cites W2061329487 @default.
• W2920200983 cites W2068919366 @default.
• W2920200983 cites W2079408140 @default.
• W2920200983 cites W2090648810 @default.
• W2920200983 cites W2090789862 @default.
• W2920200983 cites W2093887297 @default.
• W2920200983 cites W2118167935 @default.
• W2920200983 cites W2167324724 @default.
• W2920200983 cites W2169246212 @default.
• W2920200983 cites W2284518822 @default.
• W2920200983 cites W2343355344 @default.
• W2920200983 cites W2343715512 @default.
• W2920200983 cites W2346437270 @default.
• W2920200983 cites W2516804390 @default.
• W2920200983 cites W2551569844 @default.
• W2920200983 cites W2622978308 @default.
• W2920200983 cites W2742324210 @default.
• W2920200983 cites W2783115664 @default.
• W2920200983 cites W2794393820 @default.
• W2920200983 doi "https://doi.org/10.3892/ol.2019.10091" @default.
• W2920200983 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6444392" @default.
• W2920200983 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30944649" @default.
• W2920200983 hasPublicationYear "2019" @default.
• W2920200983 type Work @default.
• W2920200983 sameAs 2920200983 @default.
• W2920200983 citedByCount "3" @default.
• W2920200983 countsByYear W29202009832019 @default.
• W2920200983 countsByYear W29202009832022 @default.
• W2920200983 crossrefType "journal-article" @default.
• W2920200983 hasAuthorship W2920200983A5014028086 @default.
• W2920200983 hasAuthorship W2920200983A5027904854 @default.
• W2920200983 hasAuthorship W2920200983A5028066952 @default.
• W2920200983 hasAuthorship W2920200983A5042665218 @default.
• W2920200983 hasAuthorship W2920200983A5042791790 @default.
• W2920200983 hasAuthorship W2920200983A5054418515 @default.
• W2920200983 hasAuthorship W2920200983A5058554971 @default.
• W2920200983 hasAuthorship W2920200983A5076246947 @default.
• W2920200983 hasBestOaLocation W29202009831 @default.
• W2920200983 hasConcept C121608353 @default.
• W2920200983 hasConcept C126322002 @default.
• W2920200983 hasConcept C142724271 @default.
• W2920200983 hasConcept C146357865 @default.
• W2920200983 hasConcept C151730666 @default.
• W2920200983 hasConcept C207886595 @default.
• W2920200983 hasConcept C2777472916 @default.
• W2920200983 hasConcept C2778560582 @default.
• W2920200983 hasConcept C2778886567 @default.
• W2920200983 hasConcept C2779134260 @default.
• W2920200983 hasConcept C2780091579 @default.
• W2920200983 hasConcept C2780227381 @default.
• W2920200983 hasConcept C2781278892 @default.
• W2920200983 hasConcept C29537977 @default.
• W2920200983 hasConcept C67082663 @default.
• W2920200983 hasConcept C71924100 @default.
• W2920200983 hasConcept C78795084 @default.
• W2920200983 hasConcept C86803240 @default.
• W2920200983 hasConceptScore W2920200983C121608353 @default.
• W2920200983 hasConceptScore W2920200983C126322002 @default.
• W2920200983 hasConceptScore W2920200983C142724271 @default.
• W2920200983 hasConceptScore W2920200983C146357865 @default.
• W2920200983 hasConceptScore W2920200983C151730666 @default.
• W2920200983 hasConceptScore W2920200983C207886595 @default.
• W2920200983 hasConceptScore W2920200983C2777472916 @default.
• W2920200983 hasConceptScore W2920200983C2778560582 @default.
• W2920200983 hasConceptScore W2920200983C2778886567 @default.
• W2920200983 hasConceptScore W2920200983C2779134260 @default.
• W2920200983 hasConceptScore W2920200983C2780091579 @default.
• W2920200983 hasConceptScore W2920200983C2780227381 @default.
• W2920200983 hasConceptScore W2920200983C2781278892 @default.
• W2920200983 hasConceptScore W2920200983C29537977 @default.
• W2920200983 hasConceptScore W2920200983C67082663 @default.
• W2920200983 hasConceptScore W2920200983C71924100 @default.
• W2920200983 hasConceptScore W2920200983C78795084 @default.
• W2920200983 hasConceptScore W2920200983C86803240 @default.
• W2920200983 hasLocation W29202009831 @default.
• W2920200983 hasLocation W29202009832 @default.
• W2920200983 hasLocation W29202009833 @default.
• W2920200983 hasLocation W29202009834 @default.

• next