FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2920335274> ?p ?o ?g. }

• W2920335274 abstract "Histopathological differences in horses infected with equine herpesvirus type 1 (EHV-1) of differing neuropathogenic potential [wild-type (Ab4), polymerase mutant (Ab4 N752), EHV-1/4 gD mutant (Ab4 gD4)] were evaluated to examine the impact of viral factors on clinical disease, tissue tropism and pathology. Three of 8 Ab4 infected horses developed Equine Herpesvirus Myeloencephalopathy (EHM) requiring euthanasia of 2 horses on day 9 post-infection. None of the other horses showed neurologic signs and all remaining animals were sacrificed 10 weeks post-infection. EHM horses had lymphohistiocytic vasculitis and lymphocytic infiltrates in the lungs, spinal cord, endometrium and eyes. EHV-1 antigen was detected within the eyes and spinal cord. In 3/6 of the remaining Ab4 infected horses, 4/9 Ab4 N752 infected horses, and 8/8 Ab4 gD4 infected horses, choroiditis was observed. All males had interstitial lymphoplasmacytic and/or histiocytic orchitis and EHV-1 antigen was detected. In conclusion, only animals sacrificed due to EHM developed overt vasculitis in the CNS and the eye. Mild choroiditis persisted in many animals and appeared to be more common in Ab4 gD4 infected animals. Finally, we report infiltrates and changes in the reproductive organs of all males associated with EHV-1 antigen. While the exact significance of these changes is unclear, these findings raise concern for long-term effects on reproduction and prolonged shedding of virus through semen." @default.
• W2920335274 created "2019-03-11" @default.
• W2920335274 creator A5000353089 @default.
• W2920335274 creator A5003198305 @default.
• W2920335274 creator A5009363036 @default.
• W2920335274 creator A5062298983 @default.
• W2920335274 creator A5085344571 @default.
• W2920335274 creator A5089997890 @default.
• W2920335274 date "2019-03-04" @default.
• W2920335274 modified "2023-10-18" @default.
• W2920335274 title "Histopathologic Findings Following Experimental Equine Herpesvirus 1 Infection of Horses" @default.
• W2920335274 cites W1223737510 @default.
• W2920335274 cites W1584598921 @default.
• W2920335274 cites W1965370551 @default.
• W2920335274 cites W1996915304 @default.
• W2920335274 cites W1998159972 @default.
• W2920335274 cites W2001410333 @default.
• W2920335274 cites W2002953288 @default.
• W2920335274 cites W2018992544 @default.
• W2920335274 cites W2023498118 @default.
• W2920335274 cites W2032865163 @default.
• W2920335274 cites W2048683674 @default.
• W2920335274 cites W2050451979 @default.
• W2920335274 cites W2054930050 @default.
• W2920335274 cites W2057571516 @default.
• W2920335274 cites W2060146656 @default.
• W2920335274 cites W2072926676 @default.
• W2920335274 cites W2073861055 @default.
• W2920335274 cites W2073876601 @default.
• W2920335274 cites W2075487677 @default.
• W2920335274 cites W2079537889 @default.
• W2920335274 cites W2080203891 @default.
• W2920335274 cites W2086996704 @default.
• W2920335274 cites W2089970346 @default.
• W2920335274 cites W2090422147 @default.
• W2920335274 cites W2098301202 @default.
• W2920335274 cites W2102139081 @default.
• W2920335274 cites W2107344412 @default.
• W2920335274 cites W2109261688 @default.
• W2920335274 cites W2109405327 @default.
• W2920335274 cites W2136149552 @default.
• W2920335274 cites W2152243579 @default.
• W2920335274 cites W2161315452 @default.
• W2920335274 cites W2165142761 @default.
• W2920335274 cites W2167022679 @default.
• W2920335274 cites W2171324876 @default.
• W2920335274 cites W2172058232 @default.
• W2920335274 cites W2234065549 @default.
• W2920335274 cites W2235050815 @default.
• W2920335274 cites W2298682040 @default.
• W2920335274 cites W2316109945 @default.
• W2920335274 cites W2346895333 @default.
• W2920335274 cites W2414541769 @default.
• W2920335274 cites W2468221292 @default.
• W2920335274 cites W2511168252 @default.
• W2920335274 cites W2519621949 @default.
• W2920335274 cites W2643405330 @default.
• W2920335274 cites W4242534526 @default.
• W2920335274 cites W58489445 @default.
• W2920335274 doi "https://doi.org/10.3389/fvets.2019.00059" @default.
• W2920335274 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6409500" @default.
• W2920335274 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30886853" @default.
• W2920335274 hasPublicationYear "2019" @default.
• W2920335274 type Work @default.
• W2920335274 sameAs 2920335274 @default.
• W2920335274 citedByCount "15" @default.
• W2920335274 countsByYear W29203352742019 @default.
• W2920335274 countsByYear W29203352742020 @default.
• W2920335274 countsByYear W29203352742021 @default.
• W2920335274 countsByYear W29203352742022 @default.
• W2920335274 countsByYear W29203352742023 @default.
• W2920335274 crossrefType "journal-article" @default.
• W2920335274 hasAuthorship W2920335274A5000353089 @default.
• W2920335274 hasAuthorship W2920335274A5003198305 @default.
• W2920335274 hasAuthorship W2920335274A5009363036 @default.
• W2920335274 hasAuthorship W2920335274A5062298983 @default.
• W2920335274 hasAuthorship W2920335274A5085344571 @default.
• W2920335274 hasAuthorship W2920335274A5089997890 @default.
• W2920335274 hasBestOaLocation W29203352741 @default.
• W2920335274 hasConcept C118552586 @default.
• W2920335274 hasConcept C142724271 @default.
• W2920335274 hasConcept C151730666 @default.
• W2920335274 hasConcept C159047783 @default.
• W2920335274 hasConcept C203014093 @default.
• W2920335274 hasConcept C2522874641 @default.
• W2920335274 hasConcept C2775976905 @default.
• W2920335274 hasConcept C2776015282 @default.
• W2920335274 hasConcept C2776409557 @default.
• W2920335274 hasConcept C2779134260 @default.
• W2920335274 hasConcept C2780727368 @default.
• W2920335274 hasConcept C2780762169 @default.
• W2920335274 hasConcept C2780775167 @default.
• W2920335274 hasConcept C35693153 @default.
• W2920335274 hasConcept C71924100 @default.
• W2920335274 hasConcept C86803240 @default.
• W2920335274 hasConceptScore W2920335274C118552586 @default.
• W2920335274 hasConceptScore W2920335274C142724271 @default.
• W2920335274 hasConceptScore W2920335274C151730666 @default.
• W2920335274 hasConceptScore W2920335274C159047783 @default.
• W2920335274 hasConceptScore W2920335274C203014093 @default.

• next