FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2920394562> ?p ?o ?g. }

• W2920394562 endingPage "217" @default.
• W2920394562 startingPage "209" @default.
• W2920394562 abstract "Orodispersible films (ODFs) have a high potential to accelerate the individualized medication. The films can be produced as drug-free templates and subsequently printed with an API (active pharmaceutical ingredient) solution or suspension according to the needs of the patient. While the printing technology already enables a precise dosing of fluids, there is still a high need of suitable, edible templates with elevated loading capacity. The structured orodispersible film templates (SOFTs) developed in this study should overcome this void. The SOFTs are pervaded with pores to realize a high API load into the film structure and possess a closed bottom side to prevent the printed fluids to pass through the film. They consist of a water-soluble cellulose derivative and are produced with the solvent casting method. This study focused on the influence of the formulation of the film casting mass on the film properties, like porosity and disintegration time due to changed pore sizes and numbers. Due to the porous film structure a mass load of up to 6.1 mg cm-2 could be realized already in SOFTs, but, higher loads are feasible. The mechanical film properties could further be improved by additional matrix material in the suspension formulation, also inhibiting particle agglomeration and aggregation during the drying process, and positively influencing the dissolution behavior of the applied nanoparticles. An application of a protection layer on top of the loaded SOFTs improves the handling safety by inhibiting contact to the API and it prevents a removal of the particles from the film surface." @default.
• W2920394562 created "2019-03-11" @default.
• W2920394562 creator A5005901248 @default.
• W2920394562 creator A5057988130 @default.
• W2920394562 creator A5081584453 @default.
• W2920394562 date "2019-04-01" @default.
• W2920394562 modified "2023-09-24" @default.
• W2920394562 title "SOFTs – Structured orodispersible film templates" @default.
• W2920394562 cites W1842673738 @default.
• W2920394562 cites W1892588048 @default.
• W2920394562 cites W1917517659 @default.
• W2920394562 cites W1984992915 @default.
• W2920394562 cites W1992631805 @default.
• W2920394562 cites W2007974867 @default.
• W2920394562 cites W2008934600 @default.
• W2920394562 cites W2047667390 @default.
• W2920394562 cites W2051497948 @default.
• W2920394562 cites W2054115461 @default.
• W2920394562 cites W2066027172 @default.
• W2920394562 cites W2072066319 @default.
• W2920394562 cites W2082715589 @default.
• W2920394562 cites W2086071452 @default.
• W2920394562 cites W2093699525 @default.
• W2920394562 cites W2171865969 @default.
• W2920394562 cites W2340805991 @default.
• W2920394562 cites W2475561070 @default.
• W2920394562 cites W2493825632 @default.
• W2920394562 cites W2727286339 @default.
• W2920394562 doi "https://doi.org/10.1016/j.ejpb.2019.03.001" @default.
• W2920394562 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30836181" @default.
• W2920394562 hasPublicationYear "2019" @default.
• W2920394562 type Work @default.
• W2920394562 sameAs 2920394562 @default.
• W2920394562 citedByCount "11" @default.
• W2920394562 countsByYear W29203945622020 @default.
• W2920394562 countsByYear W29203945622021 @default.
• W2920394562 countsByYear W29203945622022 @default.
• W2920394562 countsByYear W29203945622023 @default.
• W2920394562 crossrefType "journal-article" @default.
• W2920394562 hasAuthorship W2920394562A5005901248 @default.
• W2920394562 hasAuthorship W2920394562A5057988130 @default.
• W2920394562 hasAuthorship W2920394562A5081584453 @default.
• W2920394562 hasConcept C105341887 @default.
• W2920394562 hasConcept C111368507 @default.
• W2920394562 hasConcept C127313418 @default.
• W2920394562 hasConcept C127413603 @default.
• W2920394562 hasConcept C155672457 @default.
• W2920394562 hasConcept C159985019 @default.
• W2920394562 hasConcept C16635281 @default.
• W2920394562 hasConcept C171250308 @default.
• W2920394562 hasConcept C191897082 @default.
• W2920394562 hasConcept C192562407 @default.
• W2920394562 hasConcept C202444582 @default.
• W2920394562 hasConcept C2776081644 @default.
• W2920394562 hasConcept C2778517922 @default.
• W2920394562 hasConcept C2781218482 @default.
• W2920394562 hasConcept C33923547 @default.
• W2920394562 hasConcept C42360764 @default.
• W2920394562 hasConcept C45904493 @default.
• W2920394562 hasConcept C521977710 @default.
• W2920394562 hasConcept C537181965 @default.
• W2920394562 hasConcept C5961521 @default.
• W2920394562 hasConcept C60644358 @default.
• W2920394562 hasConcept C6648577 @default.
• W2920394562 hasConcept C82714645 @default.
• W2920394562 hasConcept C86803240 @default.
• W2920394562 hasConcept C88380143 @default.
• W2920394562 hasConceptScore W2920394562C105341887 @default.
• W2920394562 hasConceptScore W2920394562C111368507 @default.
• W2920394562 hasConceptScore W2920394562C127313418 @default.
• W2920394562 hasConceptScore W2920394562C127413603 @default.
• W2920394562 hasConceptScore W2920394562C155672457 @default.
• W2920394562 hasConceptScore W2920394562C159985019 @default.
• W2920394562 hasConceptScore W2920394562C16635281 @default.
• W2920394562 hasConceptScore W2920394562C171250308 @default.
• W2920394562 hasConceptScore W2920394562C191897082 @default.
• W2920394562 hasConceptScore W2920394562C192562407 @default.
• W2920394562 hasConceptScore W2920394562C202444582 @default.
• W2920394562 hasConceptScore W2920394562C2776081644 @default.
• W2920394562 hasConceptScore W2920394562C2778517922 @default.
• W2920394562 hasConceptScore W2920394562C2781218482 @default.
• W2920394562 hasConceptScore W2920394562C33923547 @default.
• W2920394562 hasConceptScore W2920394562C42360764 @default.
• W2920394562 hasConceptScore W2920394562C45904493 @default.
• W2920394562 hasConceptScore W2920394562C521977710 @default.
• W2920394562 hasConceptScore W2920394562C537181965 @default.
• W2920394562 hasConceptScore W2920394562C5961521 @default.
• W2920394562 hasConceptScore W2920394562C60644358 @default.
• W2920394562 hasConceptScore W2920394562C6648577 @default.
• W2920394562 hasConceptScore W2920394562C82714645 @default.
• W2920394562 hasConceptScore W2920394562C86803240 @default.
• W2920394562 hasConceptScore W2920394562C88380143 @default.
• W2920394562 hasFunder F4320313139 @default.
• W2920394562 hasLocation W29203945621 @default.
• W2920394562 hasLocation W29203945622 @default.
• W2920394562 hasOpenAccess W2920394562 @default.
• W2920394562 hasPrimaryLocation W29203945621 @default.
• W2920394562 hasRelatedWork W2043535345 @default.

• next