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• W2920464915 endingPage "163" @default.
• W2920464915 startingPage "131" @default.
• W2920464915 abstract "Glycan molecular-technology-based methods to control biodistributions and in vivo kinetics of proteins and cells are reviewed here. Several chemical methods were found to conjugate various mono- and oligosaccharides onto protein surfaces. The kinetics and organ-specific accumulation profiles of these glycoconjugates intravenously injected into mouse models have been extensively analyzed by conventional dissection studies, as well as noninvasive methods such as SPECT, PET, and fluorescence imaging. These results suggest that glycan-dependent protein distribution kinetics may be useful in the development of future diagnostic and therapeutic applications. A newly emerging synthetic in vivo molecular technology is also introduced, which exploits these glycoconjugates as targeting vectors to facilitate localized, metal-catalyzed organic transformations within living organisms." @default.
• W2920464915 created "2019-03-11" @default.
• W2920464915 creator A5061443765 @default.
• W2920464915 date "2019-02-27" @default.
• W2920464915 modified "2023-09-26" @default.
• W2920464915 title "Glycan Molecular Technology for Highly Selective <i>In Vivo</i> Recognition" @default.
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