FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2920736239> ?p ?o ?g. }

• W2920736239 endingPage "155932581983384" @default.
• W2920736239 startingPage "155932581983384" @default.
• W2920736239 abstract "Radiotherapy (RT) treats cancer effectively with high doses of ionizing radiation (IR) to killing cancer cells and shrinking tumors while bearing the risk of developing different side effects, including secondary cancer, which is most concerning for long-term health consequences. Genomic instability (GI) is a characteristic of most cancer cells, and IR-induced GI can manifest as delayed homologous recombination (HR). Radioadaptive response (RAR) is capable of reducing genotoxicity, cell transformation, mutation, and carcinogenesis, but the rational evidence describing its contributions to the reduction of radiation risk, in particular, carcinogenesis, remains fragmented. In this work, to investigate the impact of RAR on high-dose, IR-induced GI measured as delayed HR, the frequency of recombinant cells was comparatively studied under RAR-inducible and -uninducible conditions in the nucleated cells in hematopoietic tissues (bone marrow and spleen) using the Rosa26 Direct Repeat-green fluorescent protein (RaDR-GFP) homozygote mice. Results demonstrated that the frequency of recombinant cells was significantly lower in hematopoietic tissues under RAR-inducible condition. These findings suggest that reduction in delayed HR may be at least a part of the mechanisms underlying decreased carcinogenesis by RAR, and application of RAR would contribute to a more rigorous and scientifically grounded system of radiation protection in RT." @default.
• W2920736239 created "2019-03-11" @default.
• W2920736239 creator A5003433901 @default.
• W2920736239 creator A5040040696 @default.
• W2920736239 creator A5064253191 @default.
• W2920736239 creator A5074581569 @default.
• W2920736239 creator A5087387711 @default.
• W2920736239 creator A5087401551 @default.
• W2920736239 creator A5089334540 @default.
• W2920736239 date "2019-01-01" @default.
• W2920736239 modified "2023-09-23" @default.
• W2920736239 title "Reduction of Delayed Homologous Recombination by Induction of Radioadaptive Response in RaDR-GFP Mice (Yonezawa Effect): An Old Player With a New Role" @default.
• W2920736239 cites W1537707737 @default.
• W2920736239 cites W1538419182 @default.
• W2920736239 cites W1981587077 @default.
• W2920736239 cites W1991774681 @default.
• W2920736239 cites W1994840889 @default.
• W2920736239 cites W1995981964 @default.
• W2920736239 cites W2001263259 @default.
• W2920736239 cites W2002233914 @default.
• W2920736239 cites W2004282309 @default.
• W2920736239 cites W2008700492 @default.
• W2920736239 cites W2009836431 @default.
• W2920736239 cites W2020089194 @default.
• W2920736239 cites W2031342026 @default.
• W2920736239 cites W2056369119 @default.
• W2920736239 cites W2060953090 @default.
• W2920736239 cites W2074703731 @default.
• W2920736239 cites W2075638923 @default.
• W2920736239 cites W2078726332 @default.
• W2920736239 cites W2079352122 @default.
• W2920736239 cites W2084491525 @default.
• W2920736239 cites W2090431588 @default.
• W2920736239 cites W2095006567 @default.
• W2920736239 cites W2102971773 @default.
• W2920736239 cites W2116905348 @default.
• W2920736239 cites W2117847813 @default.
• W2920736239 cites W2125182491 @default.
• W2920736239 cites W2130256113 @default.
• W2920736239 cites W2135428117 @default.
• W2920736239 cites W2136848218 @default.
• W2920736239 cites W2143147046 @default.
• W2920736239 cites W2143660834 @default.
• W2920736239 cites W2143922291 @default.
• W2920736239 cites W2149687109 @default.
• W2920736239 cites W2152710213 @default.
• W2920736239 cites W2159885982 @default.
• W2920736239 cites W2196350061 @default.
• W2920736239 cites W2309182611 @default.
• W2920736239 cites W2427048046 @default.
• W2920736239 cites W2523918872 @default.
• W2920736239 cites W2575854861 @default.
• W2920736239 cites W2582143511 @default.
• W2920736239 cites W2586394616 @default.
• W2920736239 cites W2588778011 @default.
• W2920736239 cites W2602026850 @default.
• W2920736239 cites W2767814755 @default.
• W2920736239 cites W2811438356 @default.
• W2920736239 cites W2888085906 @default.
• W2920736239 cites W2964456975 @default.
• W2920736239 cites W4230482292 @default.
• W2920736239 cites W4239102610 @default.
• W2920736239 cites W4376595928 @default.
• W2920736239 cites W2620482351 @default.
• W2920736239 doi "https://doi.org/10.1177/1559325819833840" @default.
• W2920736239 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6402064" @default.
• W2920736239 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30858771" @default.
• W2920736239 hasPublicationYear "2019" @default.
• W2920736239 type Work @default.
• W2920736239 sameAs 2920736239 @default.
• W2920736239 citedByCount "6" @default.
• W2920736239 countsByYear W29207362392020 @default.
• W2920736239 countsByYear W29207362392021 @default.
• W2920736239 countsByYear W29207362392022 @default.
• W2920736239 countsByYear W29207362392023 @default.
• W2920736239 crossrefType "journal-article" @default.
• W2920736239 hasAuthorship W2920736239A5003433901 @default.
• W2920736239 hasAuthorship W2920736239A5040040696 @default.
• W2920736239 hasAuthorship W2920736239A5064253191 @default.
• W2920736239 hasAuthorship W2920736239A5074581569 @default.
• W2920736239 hasAuthorship W2920736239A5087387711 @default.
• W2920736239 hasAuthorship W2920736239A5087401551 @default.
• W2920736239 hasAuthorship W2920736239A5089334540 @default.
• W2920736239 hasBestOaLocation W29207362391 @default.
• W2920736239 hasConcept C102744134 @default.
• W2920736239 hasConcept C104317684 @default.
• W2920736239 hasConcept C109159458 @default.
• W2920736239 hasConcept C121608353 @default.
• W2920736239 hasConcept C142613039 @default.
• W2920736239 hasConcept C153911025 @default.
• W2920736239 hasConcept C203014093 @default.
• W2920736239 hasConcept C2780007613 @default.
• W2920736239 hasConcept C28328180 @default.
• W2920736239 hasConcept C40767141 @default.
• W2920736239 hasConcept C502942594 @default.
• W2920736239 hasConcept C54355233 @default.
• W2920736239 hasConcept C552990157 @default.
• W2920736239 hasConcept C555283112 @default.

• next