Matches in SemOpenAlex for { <https://semopenalex.org/work/W2920761495> ?p ?o ?g. }
- W2920761495 abstract "Resistance to antibiotics often evolves when bacteria encounter antibiotics. However, bacterial strains and species without any known exposure to these drugs also vary in their intrinsic susceptibility. In many cases, evolved resistance has been shown to be costly to the bacteria, such that resistant types have reduced competitiveness relative to their sensitive progenitors in the absence of antibiotics. In this study, we examined changes in the susceptibilities of 12 populations of Escherichia coli to 15 antibiotics after 2,000 and 50,000 generations without exposure to any drug. The evolved bacteria tended to become more susceptible to most antibiotics, with most of the change occurring during the first 2,000 generations, when the bacteria were undergoing rapid adaptation to their experimental conditions. On balance, our findings indicate that bacteria with low levels of intrinsic resistance can, in the absence of relevant selection, become even more susceptible to antibiotics." @default.
- W2920761495 created "2019-03-11" @default.
- W2920761495 creator A5005762958 @default.
- W2920761495 creator A5035422823 @default.
- W2920761495 creator A5072995553 @default.
- W2920761495 creator A5077792703 @default.
- W2920761495 date "2019-04-30" @default.
- W2920761495 modified "2023-10-11" @default.
- W2920761495 title "Changes in Intrinsic Antibiotic Susceptibility during a Long-Term Evolution Experiment with Escherichia coli" @default.
- W2920761495 cites W1480307447 @default.
- W2920761495 cites W1566245339 @default.
- W2920761495 cites W1601991546 @default.
- W2920761495 cites W1768787945 @default.
- W2920761495 cites W1816841406 @default.
- W2920761495 cites W1903051111 @default.
- W2920761495 cites W1922732464 @default.
- W2920761495 cites W1967600116 @default.
- W2920761495 cites W1991265385 @default.
- W2920761495 cites W1996460711 @default.
- W2920761495 cites W2016687536 @default.
- W2920761495 cites W2019293613 @default.
- W2920761495 cites W2028849916 @default.
- W2920761495 cites W2031581341 @default.
- W2920761495 cites W2033932013 @default.
- W2920761495 cites W2035525755 @default.
- W2920761495 cites W2051116946 @default.
- W2920761495 cites W2055238593 @default.
- W2920761495 cites W2059795850 @default.
- W2920761495 cites W2066286375 @default.
- W2920761495 cites W2066492436 @default.
- W2920761495 cites W2067849157 @default.
- W2920761495 cites W2068028004 @default.
- W2920761495 cites W2072290177 @default.
- W2920761495 cites W2073556554 @default.
- W2920761495 cites W2081183202 @default.
- W2920761495 cites W2087601214 @default.
- W2920761495 cites W2101019518 @default.
- W2920761495 cites W2102975216 @default.
- W2920761495 cites W2116791869 @default.
- W2920761495 cites W2118868588 @default.
- W2920761495 cites W2121444224 @default.
- W2920761495 cites W2126115772 @default.
- W2920761495 cites W2126563157 @default.
- W2920761495 cites W2128898768 @default.
- W2920761495 cites W2135331392 @default.
- W2920761495 cites W2135682495 @default.
- W2920761495 cites W2158271932 @default.
- W2920761495 cites W2182611834 @default.
- W2920761495 cites W2205740488 @default.
- W2920761495 cites W2346473307 @default.
- W2920761495 cites W2490493873 @default.
- W2920761495 cites W2511099695 @default.
- W2920761495 cites W2754780457 @default.
- W2920761495 cites W2755522297 @default.
- W2920761495 cites W2765922336 @default.
- W2920761495 cites W2884248235 @default.
- W2920761495 cites W2888840473 @default.
- W2920761495 cites W2939226595 @default.
- W2920761495 doi "https://doi.org/10.1128/mbio.00189-19" @default.
- W2920761495 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6401480" @default.
- W2920761495 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30837336" @default.
- W2920761495 hasPublicationYear "2019" @default.
- W2920761495 type Work @default.
- W2920761495 sameAs 2920761495 @default.
- W2920761495 citedByCount "19" @default.
- W2920761495 countsByYear W29207614952019 @default.
- W2920761495 countsByYear W29207614952020 @default.
- W2920761495 countsByYear W29207614952021 @default.
- W2920761495 countsByYear W29207614952022 @default.
- W2920761495 countsByYear W29207614952023 @default.
- W2920761495 crossrefType "journal-article" @default.
- W2920761495 hasAuthorship W2920761495A5005762958 @default.
- W2920761495 hasAuthorship W2920761495A5035422823 @default.
- W2920761495 hasAuthorship W2920761495A5072995553 @default.
- W2920761495 hasAuthorship W2920761495A5077792703 @default.
- W2920761495 hasBestOaLocation W29207614951 @default.
- W2920761495 hasConcept C104317684 @default.
- W2920761495 hasConcept C114851261 @default.
- W2920761495 hasConcept C139807058 @default.
- W2920761495 hasConcept C169760540 @default.
- W2920761495 hasConcept C501593827 @default.
- W2920761495 hasConcept C523546767 @default.
- W2920761495 hasConcept C54355233 @default.
- W2920761495 hasConcept C547475151 @default.
- W2920761495 hasConcept C86803240 @default.
- W2920761495 hasConcept C87590526 @default.
- W2920761495 hasConcept C89423630 @default.
- W2920761495 hasConcept C94665300 @default.
- W2920761495 hasConceptScore W2920761495C104317684 @default.
- W2920761495 hasConceptScore W2920761495C114851261 @default.
- W2920761495 hasConceptScore W2920761495C139807058 @default.
- W2920761495 hasConceptScore W2920761495C169760540 @default.
- W2920761495 hasConceptScore W2920761495C501593827 @default.
- W2920761495 hasConceptScore W2920761495C523546767 @default.
- W2920761495 hasConceptScore W2920761495C54355233 @default.
- W2920761495 hasConceptScore W2920761495C547475151 @default.
- W2920761495 hasConceptScore W2920761495C86803240 @default.
- W2920761495 hasConceptScore W2920761495C87590526 @default.
- W2920761495 hasConceptScore W2920761495C89423630 @default.
- W2920761495 hasConceptScore W2920761495C94665300 @default.