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• W2920880878 abstract "Introduction: Patients with an eating disorder (ED) can experience protracted or recurrence of gastrointestinal (GI) symptoms, even in recovery from their ED. Some patients presenting with symptoms of gastroparesis (Gp) may have a history of an ED that could be the cause of or secondarily maintain symptoms resembling Gp. We aimed to study GI symptom characteristics and gastric emptying of patients with ED history presenting with Gp symptoms. Methods: Patients (N=755) referred to our tertiary care academic medical center with symptoms suggestive of Gp from July 2013 to May 2018 completed Patient Assessment of Upper GI Symptoms (PAGI—SYM) to capture symptom severity, self—report ED history, and gastric emptying scintigraphy (GES). Results: 37 patients (4.9%) reported a history of ED (89.2% female; Table 1). Patients with ED history reported history of anorexia nervosa (n=9), bulimia nervosa (n=6), anorexia nervosa and bulimia nervosa (n=6), or a non—specified ED (n=16). Patients with ED history had a significantly greater frequency of delayed GES than those without ED history (81.1% vs. 57.8%, p=0.005; Table 1). Interestingly, this difference was explained by the greater delay by 4—hours (p=0.001) rather than at 2 hours. Of the Gp symptoms by PAGI—SYM, severity of stomach fullness and postprandial fullness were significantly greater in the patients with history of ED (Table 2). All but 4 patients with ED history reported post—prandial fullness interfering with usual activities every day up to multiple times per day over the past 3 months. Severity of early satiety and loss of appetite were also greater in those with ED history, but at trend level. Although, patients with an ED history had a significantly lower average body mass index than those without ED history, the range was large for both groups. Conclusion: Among patients with symptoms of Gp, approximately 5% report history of ED. This is the first study to report Gp symptom complaints and 4—hour GES findings in patients with ED history presenting for Gp evaluation. Patients with ED history had a greater severity of stomach fullness and post—prandial fullness with greater retention at 4 hours postprandially on GES. Clinicians should be cognizant that patients presenting with Gp symptoms may have a history of ED, particularly those who have significant 4—hour GES delay and report severe post—prandial fullness. ED history may inform differential diagnosis and treatment approach.1226_A Figure 1 No Caption available.1226_B Figure 2 No Caption available." @default.
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• W2920880878 date "2018-10-01" @default.
• W2920880878 modified "2023-09-27" @default.
• W2920880878 title "History of Eating Disorder in Patients With Gastroparesis Symptoms: More Severe Postprandial Fullness and Delayed Gastric Emptying" @default.
• W2920880878 doi "https://doi.org/10.14309/00000434-201810001-01226" @default.
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