FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2920921849> ?p ?o ?g. }

• W2920921849 abstract "You have accessJournal of UrologySexual Function/Dysfunction: Peyronie’s Disease (MP65)1 Apr 2019MP65-09 HOW UNCOMMON PENILE CURVATURES INFLUENCE CLINICAL OUTCOMES IN PATIENTS WITH PEYRONIE’S DISEASE RECEIVING COLLAGENASE CLOSTRIDIUM HYSTOLYTICUM THERAPY? Andrea Cocci*, Giorgio Ivan Russo, Gianmartin Cito, Andrea Minervini, Mauro Gacci, Sergio Serni, Pierangelo Verrienti, Bruno Giammusso, and Nicola Mondaini Andrea Cocci*Andrea Cocci* More articles by this author , Giorgio Ivan RussoGiorgio Ivan Russo More articles by this author , Gianmartin CitoGianmartin Cito More articles by this author , Andrea MinerviniAndrea Minervini More articles by this author , Mauro GacciMauro Gacci More articles by this author , Sergio SerniSergio Serni More articles by this author , Pierangelo VerrientiPierangelo Verrienti More articles by this author , Bruno GiammussoBruno Giammusso More articles by this author , and Nicola MondainiNicola Mondaini More articles by this author View All Author Informationhttps://doi.org/10.1097/01.JU.0000556921.65236.acAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVES: Patients affected by Peyronie’s disease (PD) benefit most from therapy with Collagenase Clostridium Hystolyticum (CCH). However, clinical results in patients with uncommon penile curvature (PC) have been never reported. METHODS: We retrospectively collected data of patients affected by ventrolateral PC secondary to PD. Patients received pharmacologically induced artificial erection test (intra-cavernous injection) to assess the degree of penile curvature (PC) at baseline and after the completion of the treatment. All patients underwent a modified treatment protocol, which consisted of 3 intra-lesional injections of 0.9 mg of CCH performed at 4-week intervals at the point of maximum curvature. After each injection, patients were instructed to follow a strict routine involving daily penile stretching in the intervals between injections. As previous reported, success of therapy was defined as a decrease in PC of ≥ 20° from baseline (Cocci et al. BJU Int 2018). RESULTS: A total of 65 patients were included in the analysis. Median age was 59.0 years (IQR 53.00-63.0), median curvature was 40.0° (IQR 30.0-45.0) and median duration of the disease was 12.0 years (IQR 6.5-24.0). 53 patients had ventral PC (81.54%), 7 has hourglass PC (10.77%) and 5 has shortening PC (7.69%). Median changes of PC were -20.0 (IQR -20.0, -10.0; p<0.01) in ventral PC, -20.0 (IQR -20.0, 0.0; p<0.01) in hourglass and -15.0 (IQR -15.0, -15.0; p<0.01). At one-way ANOVA test, we did not find significant differences between groups. The rate of PC success was 56.6% (30/23) in ventral PC, 57.14% (4/3) in hourglass and 20% (1/4) (p=0.29). Treatment success was not influenced by characteristics of curvature (OR= 0.66; p=0.20). CONCLUSIONS: CCH injection treatment has proven to be effective in the improvement of PC in case of uncommon curvatures, including ventrolateral, shortening and hourglass deformities. Source of Funding: None Florence, Italy; Catania, Italy; Florence, Italy; Catania, Italy; Florence, Italy© 2019 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 201Issue Supplement 4April 2019Page: e953-e953 Advertisement Copyright & Permissions© 2019 by American Urological Association Education and Research, Inc.MetricsAuthor Information Andrea Cocci* More articles by this author Giorgio Ivan Russo More articles by this author Gianmartin Cito More articles by this author Andrea Minervini More articles by this author Mauro Gacci More articles by this author Sergio Serni More articles by this author Pierangelo Verrienti More articles by this author Bruno Giammusso More articles by this author Nicola Mondaini More articles by this author Expand All Advertisement PDF downloadLoading ..." @default.
• W2920921849 created "2019-03-22" @default.
• W2920921849 creator A5006232447 @default.
• W2920921849 creator A5009778854 @default.
• W2920921849 creator A5012539089 @default.
• W2920921849 creator A5018754403 @default.
• W2920921849 creator A5037830047 @default.
• W2920921849 creator A5042036655 @default.
• W2920921849 creator A5048032405 @default.
• W2920921849 creator A5060706639 @default.
• W2920921849 creator A5087878705 @default.
• W2920921849 date "2019-04-01" @default.
• W2920921849 modified "2023-09-23" @default.
• W2920921849 title "MP65-09 HOW UNCOMMON PENILE CURVATURES INFLUENCE CLINICAL OUTCOMES IN PATIENTS WITH PEYRONIE’S DISEASE RECEIVING COLLAGENASE CLOSTRIDIUM HYSTOLYTICUM THERAPY?" @default.
• W2920921849 doi "https://doi.org/10.1097/01.ju.0000556921.65236.ac" @default.
• W2920921849 hasPublicationYear "2019" @default.
• W2920921849 type Work @default.
• W2920921849 sameAs 2920921849 @default.
• W2920921849 citedByCount "0" @default.
• W2920921849 crossrefType "journal-article" @default.
• W2920921849 hasAuthorship W2920921849A5006232447 @default.
• W2920921849 hasAuthorship W2920921849A5009778854 @default.
• W2920921849 hasAuthorship W2920921849A5012539089 @default.
• W2920921849 hasAuthorship W2920921849A5018754403 @default.
• W2920921849 hasAuthorship W2920921849A5037830047 @default.
• W2920921849 hasAuthorship W2920921849A5042036655 @default.
• W2920921849 hasAuthorship W2920921849A5048032405 @default.
• W2920921849 hasAuthorship W2920921849A5060706639 @default.
• W2920921849 hasAuthorship W2920921849A5087878705 @default.
• W2920921849 hasBestOaLocation W29209218491 @default.
• W2920921849 hasConcept C141071460 @default.
• W2920921849 hasConcept C2779145901 @default.
• W2920921849 hasConcept C2779929075 @default.
• W2920921849 hasConcept C3018271632 @default.
• W2920921849 hasConcept C3020768380 @default.
• W2920921849 hasConcept C71924100 @default.
• W2920921849 hasConceptScore W2920921849C141071460 @default.
• W2920921849 hasConceptScore W2920921849C2779145901 @default.
• W2920921849 hasConceptScore W2920921849C2779929075 @default.
• W2920921849 hasConceptScore W2920921849C3018271632 @default.
• W2920921849 hasConceptScore W2920921849C3020768380 @default.
• W2920921849 hasConceptScore W2920921849C71924100 @default.
• W2920921849 hasIssue "Supplement 4" @default.
• W2920921849 hasLocation W29209218491 @default.
• W2920921849 hasOpenAccess W2920921849 @default.
• W2920921849 hasPrimaryLocation W29209218491 @default.
• W2920921849 hasRelatedWork W1829382524 @default.
• W2920921849 hasRelatedWork W1970450214 @default.
• W2920921849 hasRelatedWork W2054808153 @default.
• W2920921849 hasRelatedWork W2171098927 @default.
• W2920921849 hasRelatedWork W2282550812 @default.
• W2920921849 hasRelatedWork W2327716609 @default.
• W2920921849 hasRelatedWork W2933911947 @default.
• W2920921849 hasRelatedWork W2934390355 @default.
• W2920921849 hasRelatedWork W4308154535 @default.
• W2920921849 hasRelatedWork W2281914468 @default.
• W2920921849 hasVolume "201" @default.
• W2920921849 isParatext "false" @default.
• W2920921849 isRetracted "false" @default.
• W2920921849 magId "2920921849" @default.
• W2920921849 workType "article" @default.