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- W2920956886 abstract "Peste des petits ruminants (PPR) is an endemic disease of small ruminants in Nigeria and routine vaccination is the mainstay for its prevention and control. This study was aimed to assess PPR antibodies in vaccinated pregnant does and subsequent maternal immunity in their kids post parturition (PP). Twelve apparently healthy pregnant Kano brown does were used for this study. Pregnancy (third trimester) was confirmed by ultrasonography. Does were vaccinated using Nigerian 75/1 PPR strain vaccine produced by the National Veterinary Research Institute (NVRI) Vom, Nigeria. Blood was collected from does and sera harvested pre-vaccination (PrV), one week post vaccination (PV) and at two weeks interval for up to 12 weeks PP. Sera were collected from kids at two weeks of age and at two weeks interval for up to 12 weeks PP. Sera were tested for PPR antibodies using competitive enzyme linked immunosorbent assay (c-ELISA). Results showed that 100% of vaccinated does had and maintained protective PPR antibodies PV. There was significant difference (P < 0.05) in mean PPR c-ELISA antibodies PrV and PV, but no significant difference (P < 0.05) at different time intervals PV. Kids had protective maternal PPR antibodies up to four weeks (100% = 6 kids), six weeks (83.3% = 5 kids), eight weeks (50% = 3 kids), 10 weeks (16.7% = 1 kid) and none (0%) at 12 weeks PP. In conclusion, vaccination of pregnant does against PPR provided protective maternal immunity in their kids. It is recommended that Kano brown kids of vaccinated does be immunized by 10 weeks of age." @default.
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- W2920956886 date "2019-05-01" @default.
- W2920956886 modified "2023-10-11" @default.
- W2920956886 title "Assessment of Peste des petits ruminants antibodies in vaccinated pregnant Kano brown does from Nigeria and subsequent maternal immunity in their kids" @default.
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- W2920956886 doi "https://doi.org/10.1016/j.smallrumres.2019.03.009" @default.
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