FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2920996891> ?p ?o ?g. }

• W2920996891 abstract "There is a growing interest in new methods to generate bio-inspired, chemically diverse, sequence-defined synthetic polymers. Solid-phase submonomer approaches offer facile access to these types of materials, since they take advantage of readily available synthons. Submonomer approaches to date have been applied to peptidomimetics with oligo-amide backbones. Here we extend the approach to a phosphorous-containing backbone, where N-substituted phosphoramidate oligomers are constructed from a set of amine submonomers, diphenyl H-phosphonate, and cyclohexane diol. The key chemical steps in chain elongation are a chain extension reaction based on H-phosphonate (P III) chemistry, and a side chain attachment step based on the Atherton-Todd reaction. Cheap, stable chemical reagents are used without heating, all reaction times are 30 minutes or less and open to air, and no main-chain protecting groups are required. Phosphoramitoid tetramers and pentamers displaying a variety of side chain functionalities were synthesized by a three-step solid-phase submonomer method, typically with >85% crude purities." @default.
• W2920996891 created "2019-03-22" @default.
• W2920996891 creator A5013752136 @default.
• W2920996891 creator A5024089820 @default.
• W2920996891 creator A5091725897 @default.
• W2920996891 date "2019-03-13" @default.
• W2920996891 modified "2023-09-26" @default.
• W2920996891 title "Phosphoramitoids—A submonomer approach to sequence defined N ‐substituted phosphoramidate polymers" @default.
• W2920996891 cites W1966120877 @default.
• W2920996891 cites W1970597973 @default.
• W2920996891 cites W1987800184 @default.
• W2920996891 cites W1988111791 @default.
• W2920996891 cites W1994944007 @default.
• W2920996891 cites W1995024825 @default.
• W2920996891 cites W1999848871 @default.
• W2920996891 cites W2004531868 @default.
• W2920996891 cites W2007487132 @default.
• W2920996891 cites W2014539101 @default.
• W2920996891 cites W2014717165 @default.
• W2920996891 cites W2017112096 @default.
• W2920996891 cites W2020538610 @default.
• W2920996891 cites W2029659094 @default.
• W2920996891 cites W2031043408 @default.
• W2920996891 cites W2036859000 @default.
• W2920996891 cites W2043884644 @default.
• W2920996891 cites W2044337834 @default.
• W2920996891 cites W2050289195 @default.
• W2920996891 cites W2058289726 @default.
• W2920996891 cites W2135090970 @default.
• W2920996891 cites W2149681664 @default.
• W2920996891 cites W2161717388 @default.
• W2920996891 cites W2318821151 @default.
• W2920996891 cites W2326145513 @default.
• W2920996891 cites W2623628426 @default.
• W2920996891 cites W2950260686 @default.
• W2920996891 cites W2950470571 @default.
• W2920996891 cites W2953350388 @default.
• W2920996891 cites W4234803768 @default.
• W2920996891 cites W4249829561 @default.
• W2920996891 cites W45043595 @default.
• W2920996891 doi "https://doi.org/10.1002/bip.23268" @default.
• W2920996891 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30866037" @default.
• W2920996891 hasPublicationYear "2019" @default.
• W2920996891 type Work @default.
• W2920996891 sameAs 2920996891 @default.
• W2920996891 citedByCount "1" @default.
• W2920996891 countsByYear W29209968912023 @default.
• W2920996891 crossrefType "journal-article" @default.
• W2920996891 hasAuthorship W2920996891A5013752136 @default.
• W2920996891 hasAuthorship W2920996891A5024089820 @default.
• W2920996891 hasAuthorship W2920996891A5091725897 @default.
• W2920996891 hasConcept C131779359 @default.
• W2920996891 hasConcept C178790620 @default.
• W2920996891 hasConcept C185592680 @default.
• W2920996891 hasConcept C188027245 @default.
• W2920996891 hasConcept C204921945 @default.
• W2920996891 hasConcept C21951064 @default.
• W2920996891 hasConcept C2776469878 @default.
• W2920996891 hasConcept C2777626080 @default.
• W2920996891 hasConcept C2778112365 @default.
• W2920996891 hasConcept C2778439535 @default.
• W2920996891 hasConcept C2779281246 @default.
• W2920996891 hasConcept C2779515768 @default.
• W2920996891 hasConcept C2780880337 @default.
• W2920996891 hasConcept C40869318 @default.
• W2920996891 hasConcept C40875361 @default.
• W2920996891 hasConcept C521977710 @default.
• W2920996891 hasConcept C55493867 @default.
• W2920996891 hasConcept C71240020 @default.
• W2920996891 hasConceptScore W2920996891C131779359 @default.
• W2920996891 hasConceptScore W2920996891C178790620 @default.
• W2920996891 hasConceptScore W2920996891C185592680 @default.
• W2920996891 hasConceptScore W2920996891C188027245 @default.
• W2920996891 hasConceptScore W2920996891C204921945 @default.
• W2920996891 hasConceptScore W2920996891C21951064 @default.
• W2920996891 hasConceptScore W2920996891C2776469878 @default.
• W2920996891 hasConceptScore W2920996891C2777626080 @default.
• W2920996891 hasConceptScore W2920996891C2778112365 @default.
• W2920996891 hasConceptScore W2920996891C2778439535 @default.
• W2920996891 hasConceptScore W2920996891C2779281246 @default.
• W2920996891 hasConceptScore W2920996891C2779515768 @default.
• W2920996891 hasConceptScore W2920996891C2780880337 @default.
• W2920996891 hasConceptScore W2920996891C40869318 @default.
• W2920996891 hasConceptScore W2920996891C40875361 @default.
• W2920996891 hasConceptScore W2920996891C521977710 @default.
• W2920996891 hasConceptScore W2920996891C55493867 @default.
• W2920996891 hasConceptScore W2920996891C71240020 @default.
• W2920996891 hasIssue "4" @default.
• W2920996891 hasLocation W29209968911 @default.
• W2920996891 hasLocation W29209968912 @default.
• W2920996891 hasOpenAccess W2920996891 @default.
• W2920996891 hasPrimaryLocation W29209968911 @default.
• W2920996891 hasRelatedWork W1987755785 @default.
• W2920996891 hasRelatedWork W1993896944 @default.
• W2920996891 hasRelatedWork W2020183541 @default.
• W2920996891 hasRelatedWork W2025007445 @default.
• W2920996891 hasRelatedWork W2134324855 @default.
• W2920996891 hasRelatedWork W2899565859 @default.
• W2920996891 hasRelatedWork W2920996891 @default.
• W2920996891 hasRelatedWork W2949138808 @default.

• next