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- W2921017227 abstract "Lantibiotics are a class of peptide antibiotics with activity against most Gram-positive bacteria. Lanthionine (Lan) and β-MeLan are unusual thioether-bridged, non-proteinogenic amino acids, which are characteristic features of lantibiotics. In this paper, we report the facile stereoselective synthesis of β-methyllanthionines with orthogonal protection by nucleophilic ring opening of aziridines. This method leads to an expedient access to β-methyllanthionines and allows production of over 30 g of β-methyllanthionine in a single batch." @default.
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- W2921017227 date "2019-03-11" @default.
- W2921017227 modified "2023-09-26" @default.
- W2921017227 title "Scalable Synthesis of Orthogonally Protected β-Methyllanthionines by Indium(III)-Mediated Ring Opening of Aziridines" @default.
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- W2921017227 doi "https://doi.org/10.1021/acs.orglett.9b00125" @default.
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