Matches in SemOpenAlex for { <https://semopenalex.org/work/W2921054427> ?p ?o ?g. }
- W2921054427 endingPage "375" @default.
- W2921054427 startingPage "368" @default.
- W2921054427 abstract "This study aimed to identify critical physiological outcome variables underlying reduced upper extremity task performance in Duchenne muscular dystrophy (DMD). These critical variables were used to propose an explanatory biophysical model of the upper extremity working mechanisms in DMD. Twenty-three DMD patients (8–21 years) participated in this study. Correlations with Brooke scale and Performance of Upper Limb (PUL) score were very high for maximal active joint angle, high for maximal muscle torque and maximal surface electromyography amplitude, and moderate for mean echogenicity and maximal passive joint angle. Multivariable regression analysis showed that maximal active joint angle and maximal muscle torque were significantly associated with Brooke score (R2 = 0.91). Maximal active joint angle, maximal passive joint angle, and maximal muscle torque were significantly associated with PUL score (R2 = 0.94). Based on the most critical physiological outcome variables, we constructed an exploratory biophysical model of the working mechanisms leading to limitations in upper extremity task performance. Better insights in these working mechanisms could support clinical management of upper extremity limitations and facilitate the development of interventions. In addition, the model could form the basis for new multi-layered outcome measures for clinical trials." @default.
- W2921054427 created "2019-03-22" @default.
- W2921054427 creator A5015519090 @default.
- W2921054427 creator A5016167410 @default.
- W2921054427 creator A5041310576 @default.
- W2921054427 creator A5055507077 @default.
- W2921054427 date "2019-05-01" @default.
- W2921054427 modified "2023-10-18" @default.
- W2921054427 title "Unraveling upper extremity performance in Duchenne muscular dystrophy: A biophysical model" @default.
- W2921054427 cites W10680619 @default.
- W2921054427 cites W1486663246 @default.
- W2921054427 cites W1526250243 @default.
- W2921054427 cites W1558196299 @default.
- W2921054427 cites W1596515083 @default.
- W2921054427 cites W1966413061 @default.
- W2921054427 cites W1975139695 @default.
- W2921054427 cites W1987369104 @default.
- W2921054427 cites W1987791972 @default.
- W2921054427 cites W2000912972 @default.
- W2921054427 cites W2004904112 @default.
- W2921054427 cites W2011692833 @default.
- W2921054427 cites W2021001258 @default.
- W2921054427 cites W2023324665 @default.
- W2921054427 cites W2024011757 @default.
- W2921054427 cites W2026121313 @default.
- W2921054427 cites W2035652604 @default.
- W2921054427 cites W2043862760 @default.
- W2921054427 cites W2049094551 @default.
- W2921054427 cites W2056713865 @default.
- W2921054427 cites W2062176268 @default.
- W2921054427 cites W2072075432 @default.
- W2921054427 cites W2073563966 @default.
- W2921054427 cites W2076662962 @default.
- W2921054427 cites W2079569594 @default.
- W2921054427 cites W2082599638 @default.
- W2921054427 cites W2097024559 @default.
- W2921054427 cites W2099378066 @default.
- W2921054427 cites W2104806243 @default.
- W2921054427 cites W2112943033 @default.
- W2921054427 cites W2132091723 @default.
- W2921054427 cites W2142299200 @default.
- W2921054427 cites W2145040361 @default.
- W2921054427 cites W2149350407 @default.
- W2921054427 cites W2158739907 @default.
- W2921054427 cites W2159586986 @default.
- W2921054427 cites W2162517429 @default.
- W2921054427 cites W2320240192 @default.
- W2921054427 cites W2333684696 @default.
- W2921054427 cites W2410609393 @default.
- W2921054427 cites W2532593119 @default.
- W2921054427 cites W2617957706 @default.
- W2921054427 cites W804694437 @default.
- W2921054427 doi "https://doi.org/10.1016/j.nmd.2019.03.006" @default.
- W2921054427 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31029531" @default.
- W2921054427 hasPublicationYear "2019" @default.
- W2921054427 type Work @default.
- W2921054427 sameAs 2921054427 @default.
- W2921054427 citedByCount "8" @default.
- W2921054427 countsByYear W29210544272019 @default.
- W2921054427 countsByYear W29210544272020 @default.
- W2921054427 countsByYear W29210544272021 @default.
- W2921054427 countsByYear W29210544272023 @default.
- W2921054427 crossrefType "journal-article" @default.
- W2921054427 hasAuthorship W2921054427A5015519090 @default.
- W2921054427 hasAuthorship W2921054427A5016167410 @default.
- W2921054427 hasAuthorship W2921054427A5041310576 @default.
- W2921054427 hasAuthorship W2921054427A5055507077 @default.
- W2921054427 hasBestOaLocation W29210544272 @default.
- W2921054427 hasConcept C126322002 @default.
- W2921054427 hasConcept C1862650 @default.
- W2921054427 hasConcept C2776660947 @default.
- W2921054427 hasConcept C2777515770 @default.
- W2921054427 hasConcept C2778943923 @default.
- W2921054427 hasConcept C2779030066 @default.
- W2921054427 hasConcept C71924100 @default.
- W2921054427 hasConcept C99508421 @default.
- W2921054427 hasConceptScore W2921054427C126322002 @default.
- W2921054427 hasConceptScore W2921054427C1862650 @default.
- W2921054427 hasConceptScore W2921054427C2776660947 @default.
- W2921054427 hasConceptScore W2921054427C2777515770 @default.
- W2921054427 hasConceptScore W2921054427C2778943923 @default.
- W2921054427 hasConceptScore W2921054427C2779030066 @default.
- W2921054427 hasConceptScore W2921054427C71924100 @default.
- W2921054427 hasConceptScore W2921054427C99508421 @default.
- W2921054427 hasFunder F4320334893 @default.
- W2921054427 hasIssue "5" @default.
- W2921054427 hasLocation W29210544271 @default.
- W2921054427 hasLocation W29210544272 @default.
- W2921054427 hasLocation W29210544273 @default.
- W2921054427 hasLocation W29210544274 @default.
- W2921054427 hasOpenAccess W2921054427 @default.
- W2921054427 hasPrimaryLocation W29210544271 @default.
- W2921054427 hasRelatedWork W2006551337 @default.
- W2921054427 hasRelatedWork W2027163719 @default.
- W2921054427 hasRelatedWork W2056138909 @default.
- W2921054427 hasRelatedWork W2097967630 @default.
- W2921054427 hasRelatedWork W2156472821 @default.
- W2921054427 hasRelatedWork W2163416236 @default.