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• W2921170701 abstract "Abstract Objectives The sagittal suture (SS) is assumed to be an initial site for the commencement of cranial suture closure as well as the most frequent spot of isolated craniosynostosis. The present study aimed to inspect the reorganization of the SS at the microlevel to assess the relation between its closure and aging and to establish whether it could be used as a reliable indicator in age‐at‐death prediction. Materials and methods The SS was investigated in 68 dry contemporary adult male skulls of known age‐at‐death. An additional series of 20 skulls was used for verification. The skulls were scanned using a micro‐computed tomography system. The SS closure degree was assessed along the three bone layers on cross‐sectional tomograms by using a scoring scale. Results In the entirely open SS, the bone edges consist of compact bone and are widely separated. With SS maturation, the bone edges come into contact, and the remodeling process leads to a decrease in the sutural area and bone homogenization across all three layers. SS closure is an irregular process roughly related to aging, beginning in the early 20s, reaching its peak at about 30 years of age and abating in the late 40s. Discussion Although related to aging, SS closure is not a simple function of it. Rather, the underlying factors inducing and managing this process are multifaceted and complex. Although the etiology of SS maturation remains unclear, it is reasonable to use SS closure cautiously and only as a supportive method for age prediction." @default.
• W2921170701 created "2019-03-22" @default.
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• W2921170701 date "2019-03-08" @default.
• W2921170701 modified "2023-10-18" @default.
• W2921170701 title "Sagittal suture maturation: Morphological reorganization, relation to aging, and reliability as an age‐at‐death indicator" @default.
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• W2921170701 doi "https://doi.org/10.1002/ajpa.23810" @default.
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