FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2921210032> ?p ?o ?g. }

• W2921210032 abstract "Previous studies indicated low-intensity warfarin (INR target of 1.5-2.5) achieved reduced hemorrhage without increasing thromboembolism for Asians with non-valvular atrial fibrillation (NVAF). Whether non-vitamin K antagonist oral anticoagulant (NOAC) is superior to warfarin with good time in the therapeutic range (TTR) based on lower INR target among Asians with NVAF remains unknown.In this retrospective study collected from Taiwan Chang Gung Memorial Hospital Database, there were 5,197, 3,396, and 9,898 consecutive patients taking warfarin, NOAC, and no-treatment, respectively, from January 1, 2000 to December 31, 2015. Propensity-score weighting was used across the study groups. Patients were followed until the first occurrence of study outcome or end date of study.Among those patients taking warfarin, the meanartificial TTR (aTTR) based on a lower INR target of 1.5-2.5 was 44.4±33.3%. Total 79.2% (n = 2,690) patients took low-dose NOACs. Patients with aTTR in the range from <30%(34.0%), 30-50%(17.6%), 50-70%(23.5%) to >70%(24.9%) showed decremental risks of efficacy and composite outcome compared with no-treatment. The risk of major bleeding didn't increase among patients with top aTTR>70% compared to no-treatment. The NOAC group showed a comparable risk of composite outcome to the warfarin subgroup with aTTR of >70% (P = 0.485). The NOAC group had a lower risk of composite outcome than warfarin subgroup with TTR of>70% based on the INR target of 2.0-3.0 (P = 0.004).NOACs showed a comparable risk of efficacy, safety, and composite outcome to well-managed warfarin based on a lower INR target of 1.5-2.5 in Asians with NVAF taking oral anticoagulants." @default.
• W2921210032 created "2019-03-22" @default.
• W2921210032 creator A5006179171 @default.
• W2921210032 creator A5022005660 @default.
• W2921210032 creator A5030133821 @default.
• W2921210032 creator A5042552378 @default.
• W2921210032 creator A5051140042 @default.
• W2921210032 creator A5062329309 @default.
• W2921210032 creator A5062863585 @default.
• W2921210032 date "2019-03-18" @default.
• W2921210032 modified "2023-09-24" @default.
• W2921210032 title "The comparison of non-vitamin K antagonist oral anticoagulants versus well-managed warfarin with a lower INR target of 1.5 to 2.5 in Asians patients with non-valvular atrial fibrillation" @default.
• W2921210032 cites W1586488555 @default.
• W2921210032 cites W1709985587 @default.
• W2921210032 cites W1979299653 @default.
• W2921210032 cites W1985993462 @default.
• W2921210032 cites W1995044128 @default.
• W2921210032 cites W1999468381 @default.
• W2921210032 cites W2001603488 @default.
• W2921210032 cites W2050306424 @default.
• W2921210032 cites W2081205482 @default.
• W2921210032 cites W2085975373 @default.
• W2921210032 cites W2095647706 @default.
• W2921210032 cites W2121394112 @default.
• W2921210032 cites W2127985968 @default.
• W2921210032 cites W2136587148 @default.
• W2921210032 cites W2143847103 @default.
• W2921210032 cites W2144168223 @default.
• W2921210032 cites W2152623033 @default.
• W2921210032 cites W2165242637 @default.
• W2921210032 cites W2170421103 @default.
• W2921210032 cites W2321584584 @default.
• W2921210032 cites W2509795914 @default.
• W2921210032 cites W2553397353 @default.
• W2921210032 cites W2557545836 @default.
• W2921210032 cites W2621026111 @default.
• W2921210032 cites W2740723077 @default.
• W2921210032 cites W3004050106 @default.
• W2921210032 cites W4238531734 @default.
• W2921210032 doi "https://doi.org/10.1371/journal.pone.0213517" @default.
• W2921210032 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6422299" @default.
• W2921210032 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30883567" @default.
• W2921210032 hasPublicationYear "2019" @default.
• W2921210032 type Work @default.
• W2921210032 sameAs 2921210032 @default.
• W2921210032 citedByCount "4" @default.
• W2921210032 countsByYear W29212100322020 @default.
• W2921210032 countsByYear W29212100322021 @default.
• W2921210032 countsByYear W29212100322023 @default.
• W2921210032 crossrefType "journal-article" @default.
• W2921210032 hasAuthorship W2921210032A5006179171 @default.
• W2921210032 hasAuthorship W2921210032A5022005660 @default.
• W2921210032 hasAuthorship W2921210032A5030133821 @default.
• W2921210032 hasAuthorship W2921210032A5042552378 @default.
• W2921210032 hasAuthorship W2921210032A5051140042 @default.
• W2921210032 hasAuthorship W2921210032A5062329309 @default.
• W2921210032 hasAuthorship W2921210032A5062863585 @default.
• W2921210032 hasBestOaLocation W29212100321 @default.
• W2921210032 hasConcept C126322002 @default.
• W2921210032 hasConcept C167135981 @default.
• W2921210032 hasConcept C17923572 @default.
• W2921210032 hasConcept C187960798 @default.
• W2921210032 hasConcept C2776301958 @default.
• W2921210032 hasConcept C2776704044 @default.
• W2921210032 hasConcept C2779161974 @default.
• W2921210032 hasConcept C44249647 @default.
• W2921210032 hasConcept C71924100 @default.
• W2921210032 hasConceptScore W2921210032C126322002 @default.
• W2921210032 hasConceptScore W2921210032C167135981 @default.
• W2921210032 hasConceptScore W2921210032C17923572 @default.
• W2921210032 hasConceptScore W2921210032C187960798 @default.
• W2921210032 hasConceptScore W2921210032C2776301958 @default.
• W2921210032 hasConceptScore W2921210032C2776704044 @default.
• W2921210032 hasConceptScore W2921210032C2779161974 @default.
• W2921210032 hasConceptScore W2921210032C44249647 @default.
• W2921210032 hasConceptScore W2921210032C71924100 @default.
• W2921210032 hasFunder F4320323441 @default.
• W2921210032 hasLocation W29212100321 @default.
• W2921210032 hasLocation W29212100322 @default.
• W2921210032 hasLocation W29212100323 @default.
• W2921210032 hasLocation W29212100324 @default.
• W2921210032 hasLocation W29212100325 @default.
• W2921210032 hasLocation W29212100326 @default.
• W2921210032 hasOpenAccess W2921210032 @default.
• W2921210032 hasPrimaryLocation W29212100321 @default.
• W2921210032 hasRelatedWork W2113021651 @default.
• W2921210032 hasRelatedWork W2267354991 @default.
• W2921210032 hasRelatedWork W2625135257 @default.
• W2921210032 hasRelatedWork W2889527959 @default.
• W2921210032 hasRelatedWork W2913881190 @default.
• W2921210032 hasRelatedWork W2918554128 @default.
• W2921210032 hasRelatedWork W2947231666 @default.
• W2921210032 hasRelatedWork W2981412304 @default.
• W2921210032 hasRelatedWork W3132687559 @default.
• W2921210032 hasRelatedWork W3175289208 @default.
• W2921210032 isParatext "false" @default.
• W2921210032 isRetracted "false" @default.
• W2921210032 magId "2921210032" @default.
• W2921210032 workType "article" @default.