FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2921226392> ?p ?o ?g. }

• W2921226392 endingPage "S109" @default.
• W2921226392 startingPage "S107" @default.
• W2921226392 abstract "Introduction: C. difficile infection (CDI) is the most common cause of nosocomial diarrhea. Post-op patients (pts) have a distinctly increased risk of CDI and outcomes of such CDI are being actively investigated. We aimed to examine the time from surgery to first post-op CDI (i.e. index CDI) and to assess outcomes of post-op CDI among 3 major surgical categories, Gastrointestinal (GI), Vascular (Vasc), and Orthopedic (Ortho). Methods: We performed a retrospective study of pts who had surgery in one of 3 categories (GI, Ortho, and Vasc) and who developed CDI within 90 days of surgery. GI subgroups (intestinal [small intestine and colon], non-intestinal hollow viscera [stomach and gallbladder], and solid organ) were also analyzed. Pt characteristics between time of surgery and CDI were compared using ANOVA (for continuous variables) and Chi-squared test (for categorical variables). CDI recurrence rates were compared between groups using a Chi-squared test. Time from surgery to index CDI, all-cause mortality, and mortality related to CDI complications within 90 days after index CDI were analyzed using Kaplan-Meier curves and log-rank tests. Statistical significance was set at P<0.05. Results: We included 518 post-surgical pts (GI, n=187; Vasc, n=192; Ortho, n=139). Pts were older in Ortho and Vasc groups than in the GI group (Table 1). Compared with GI and Ortho, Vasc pts were more likely to be diabetic, have renal disease, and be immunocompromised at index CDI time. Compared with GI and Vasc, recent use of PPIs was less likely in Ortho pts. Use of antibiotics in the preceding 3 months was higher in Ortho and Vasc patients compared with GI pts. GI pts developed CDI sooner than Vasc pts after surgery (P=0.01); no other pairwise difference was noted (Figure 1). Among GI subgroups, nonintestinal hollow visceral procedures were complicated by CDI sooner than were intestinal procedures (P=0.02) (Figure 2). CDI recurrence was not significantly different between groups. All-cause mortality and mortality related to complications within 90 days from index CDI were higher in Vasc pts compared with GI pts (P=0.003 and 0.0032, respectively); no other pairwise difference was noted.191_A Figure 1. Patient Demographics and Clinical Characteristics at the time of CDI191_B Figure 2. Time from surgery to index CDI among post-surgical Gastrointestinal, Orthopedic, and Vascular patientsConclusion: Pts developed CDI sooner after GI surgery, especially non-intestinal hollow visceral surgery. Pts had higher all-cause mortality and mortality from complications of CDI at 90 days after Vasc surgery compared with GI surgery. There were no differences in mortality in Ortho pts compared with Vasc and GI pts.191_C Figure 3. Time from surgery to index CDI among post-surgical Gastrointestinal subgroups" @default.
• W2921226392 created "2019-03-22" @default.
• W2921226392 creator A5010038196 @default.
• W2921226392 creator A5021568406 @default.
• W2921226392 creator A5028140014 @default.
• W2921226392 creator A5036500041 @default.
• W2921226392 creator A5037026486 @default.
• W2921226392 creator A5037943626 @default.
• W2921226392 creator A5056008079 @default.
• W2921226392 creator A5067803286 @default.
• W2921226392 creator A5069803629 @default.
• W2921226392 date "2018-10-01" @default.
• W2921226392 modified "2023-09-27" @default.
• W2921226392 title "Outcomes and Mortality in Post-Operative C. difficile Infection: A Single Center Study" @default.
• W2921226392 doi "https://doi.org/10.14309/00000434-201810001-00191" @default.
• W2921226392 hasPublicationYear "2018" @default.
• W2921226392 type Work @default.
• W2921226392 sameAs 2921226392 @default.
• W2921226392 citedByCount "0" @default.
• W2921226392 crossrefType "journal-article" @default.
• W2921226392 hasAuthorship W2921226392A5010038196 @default.
• W2921226392 hasAuthorship W2921226392A5021568406 @default.
• W2921226392 hasAuthorship W2921226392A5028140014 @default.
• W2921226392 hasAuthorship W2921226392A5036500041 @default.
• W2921226392 hasAuthorship W2921226392A5037026486 @default.
• W2921226392 hasAuthorship W2921226392A5037943626 @default.
• W2921226392 hasAuthorship W2921226392A5056008079 @default.
• W2921226392 hasAuthorship W2921226392A5067803286 @default.
• W2921226392 hasAuthorship W2921226392A5069803629 @default.
• W2921226392 hasConcept C10515644 @default.
• W2921226392 hasConcept C126322002 @default.
• W2921226392 hasConcept C141071460 @default.
• W2921226392 hasConcept C167135981 @default.
• W2921226392 hasConcept C2776641081 @default.
• W2921226392 hasConcept C2777148285 @default.
• W2921226392 hasConcept C2779802037 @default.
• W2921226392 hasConcept C65409693 @default.
• W2921226392 hasConcept C66339696 @default.
• W2921226392 hasConcept C71924100 @default.
• W2921226392 hasConcept C90924648 @default.
• W2921226392 hasConceptScore W2921226392C10515644 @default.
• W2921226392 hasConceptScore W2921226392C126322002 @default.
• W2921226392 hasConceptScore W2921226392C141071460 @default.
• W2921226392 hasConceptScore W2921226392C167135981 @default.
• W2921226392 hasConceptScore W2921226392C2776641081 @default.
• W2921226392 hasConceptScore W2921226392C2777148285 @default.
• W2921226392 hasConceptScore W2921226392C2779802037 @default.
• W2921226392 hasConceptScore W2921226392C65409693 @default.
• W2921226392 hasConceptScore W2921226392C66339696 @default.
• W2921226392 hasConceptScore W2921226392C71924100 @default.
• W2921226392 hasConceptScore W2921226392C90924648 @default.
• W2921226392 hasIssue "Supplement" @default.
• W2921226392 hasLocation W29212263921 @default.
• W2921226392 hasOpenAccess W2921226392 @default.
• W2921226392 hasPrimaryLocation W29212263921 @default.
• W2921226392 hasRelatedWork W1985196611 @default.
• W2921226392 hasRelatedWork W2000364423 @default.
• W2921226392 hasRelatedWork W2028322447 @default.
• W2921226392 hasRelatedWork W2032781929 @default.
• W2921226392 hasRelatedWork W21140888 @default.
• W2921226392 hasRelatedWork W2320031995 @default.
• W2921226392 hasRelatedWork W2416177430 @default.
• W2921226392 hasRelatedWork W2551215869 @default.
• W2921226392 hasRelatedWork W3141712789 @default.
• W2921226392 hasRelatedWork W4282982086 @default.
• W2921226392 hasVolume "113" @default.
• W2921226392 isParatext "false" @default.
• W2921226392 isRetracted "false" @default.
• W2921226392 magId "2921226392" @default.
• W2921226392 workType "article" @default.