FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2921311512> ?p ?o ?g. }

• W2921311512 abstract "In sickle cell disease, the aberrant assembly of hemoglobin fibers induces changes in red blood cell morphology and stiffness, which leads to downstream symptoms of the disease. Therefore, understanding of this assembly process will be important for the treatment of sickle cell disease. By performing the highest spatiotemporal resolution measurements (55 nm at 1 Hz) of single sickle hemoglobin fiber assembly to date and combining them with a model that accounts for the multistranded structure of the fibers, we show that the rates of sickle hemoglobin addition and loss have been underestimated in the literature by at least an order of magnitude. These results reveal that the sickle hemoglobin self-assembly process is very rapid and inefficient (4% efficient versus 96% efficient based on previous analyses), where net growth is the small difference between over a million addition-loss events occurring every second." @default.
• W2921311512 created "2019-03-22" @default.
• W2921311512 creator A5010235753 @default.
• W2921311512 creator A5052243927 @default.
• W2921311512 creator A5088610056 @default.
• W2921311512 date "2019-03-01" @default.
• W2921311512 modified "2023-10-18" @default.
• W2921311512 title "Rapid and inefficient kinetics of sickle hemoglobin fiber growth" @default.
• W2921311512 cites W111659589 @default.
• W2921311512 cites W1504723206 @default.
• W2921311512 cites W1572474990 @default.
• W2921311512 cites W1587588813 @default.
• W2921311512 cites W1596260168 @default.
• W2921311512 cites W1601819722 @default.
• W2921311512 cites W168265165 @default.
• W2921311512 cites W1965404941 @default.
• W2921311512 cites W1980262534 @default.
• W2921311512 cites W1985701335 @default.
• W2921311512 cites W1990037275 @default.
• W2921311512 cites W2009740004 @default.
• W2921311512 cites W2012557094 @default.
• W2921311512 cites W2015005644 @default.
• W2921311512 cites W2027398076 @default.
• W2921311512 cites W2030543911 @default.
• W2921311512 cites W2033319799 @default.
• W2921311512 cites W2043130582 @default.
• W2921311512 cites W2044998117 @default.
• W2921311512 cites W2047579047 @default.
• W2921311512 cites W2054455698 @default.
• W2921311512 cites W2056977331 @default.
• W2921311512 cites W2057096287 @default.
• W2921311512 cites W2058523300 @default.
• W2921311512 cites W2062441703 @default.
• W2921311512 cites W2074113851 @default.
• W2921311512 cites W2077298760 @default.
• W2921311512 cites W2093855538 @default.
• W2921311512 cites W2132662279 @default.
• W2921311512 cites W2146453988 @default.
• W2921311512 cites W2157420503 @default.
• W2921311512 cites W2159447001 @default.
• W2921311512 cites W2171956751 @default.
• W2921311512 cites W2326476344 @default.
• W2921311512 cites W2397676076 @default.
• W2921311512 cites W2510810968 @default.
• W2921311512 cites W2605267194 @default.
• W2921311512 cites W2606557370 @default.
• W2921311512 cites W4245377377 @default.
• W2921311512 doi "https://doi.org/10.1126/sciadv.aau1086" @default.
• W2921311512 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6415962" @default.
• W2921311512 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30891490" @default.
• W2921311512 hasPublicationYear "2019" @default.
• W2921311512 type Work @default.
• W2921311512 sameAs 2921311512 @default.
• W2921311512 citedByCount "18" @default.
• W2921311512 countsByYear W29213115122019 @default.
• W2921311512 countsByYear W29213115122020 @default.
• W2921311512 countsByYear W29213115122021 @default.
• W2921311512 countsByYear W29213115122022 @default.
• W2921311512 countsByYear W29213115122023 @default.
• W2921311512 crossrefType "journal-article" @default.
• W2921311512 hasAuthorship W2921311512A5010235753 @default.
• W2921311512 hasAuthorship W2921311512A5052243927 @default.
• W2921311512 hasAuthorship W2921311512A5088610056 @default.
• W2921311512 hasBestOaLocation W29213115121 @default.
• W2921311512 hasConcept C126322002 @default.
• W2921311512 hasConcept C1491633281 @default.
• W2921311512 hasConcept C159985019 @default.
• W2921311512 hasConcept C185592680 @default.
• W2921311512 hasConcept C192562407 @default.
• W2921311512 hasConcept C2778620579 @default.
• W2921311512 hasConcept C2778917026 @default.
• W2921311512 hasConcept C2779134260 @default.
• W2921311512 hasConcept C3020314195 @default.
• W2921311512 hasConcept C519885992 @default.
• W2921311512 hasConcept C55493867 @default.
• W2921311512 hasConcept C71924100 @default.
• W2921311512 hasConceptScore W2921311512C126322002 @default.
• W2921311512 hasConceptScore W2921311512C1491633281 @default.
• W2921311512 hasConceptScore W2921311512C159985019 @default.
• W2921311512 hasConceptScore W2921311512C185592680 @default.
• W2921311512 hasConceptScore W2921311512C192562407 @default.
• W2921311512 hasConceptScore W2921311512C2778620579 @default.
• W2921311512 hasConceptScore W2921311512C2778917026 @default.
• W2921311512 hasConceptScore W2921311512C2779134260 @default.
• W2921311512 hasConceptScore W2921311512C3020314195 @default.
• W2921311512 hasConceptScore W2921311512C519885992 @default.
• W2921311512 hasConceptScore W2921311512C55493867 @default.
• W2921311512 hasConceptScore W2921311512C71924100 @default.
• W2921311512 hasFunder F4320332161 @default.
• W2921311512 hasIssue "3" @default.
• W2921311512 hasLocation W29213115121 @default.
• W2921311512 hasLocation W29213115122 @default.
• W2921311512 hasLocation W29213115123 @default.
• W2921311512 hasLocation W29213115124 @default.
• W2921311512 hasOpenAccess W2921311512 @default.
• W2921311512 hasPrimaryLocation W29213115121 @default.
• W2921311512 hasRelatedWork W1842015934 @default.
• W2921311512 hasRelatedWork W184984064 @default.
• W2921311512 hasRelatedWork W1963435794 @default.
• W2921311512 hasRelatedWork W1969284018 @default.

• next