Matches in SemOpenAlex for { <https://semopenalex.org/work/W2921402778> ?p ?o ?g. }
Showing items 1 to 87 of
87
with 100 items per page.
- W2921402778 abstract "The study aimed to evaluate the diagnostic performance of malaria through microscopy and rapid diagnostic test (RDT) analysis performed locally and the accuracy evaluated by nested polymerase chain reaction (PCR) for diagnosis of Plasmodium falciparum from hotspot regions of North East (NE) India.One thousand one hundred and seventy-three blood samples were collected for identification of P. falciparum infection using microscopy and RDT analysis. DNA was extracted from whole blood using QIAamp DNA blood mini kit, and nested PCR was performed to confirm P. falciparum for evaluating sensitivity and specificity from various epidemiological surveys and geographical areas of NE India.Of 1173 symptomatic malaria suspected patients, 15.6% (183/1173) patients were diagnosed as malaria positive by RDT and 67.94% cases (53/78) with microscopy. Of 183 malaria-positive patients, 42.62% (78/183) were diagnosed with P. falciparum and 84.61% (66/78) further confirmed to be P. falciparum positive by nested PCR. High sensitivity (97.9%) and low specificity (2.03%) of the RDT and high sensitivity (99.1%) and low specificity (0.9%) in microscopy against nested PCR results was statistically significant (P < 0.05). Epidemiological comparisons expressed highest incidences in Manipur (51.11%) followed by Meghalaya (48.93%) and Assam (35.16%). Overall incidence rate among the genders was observed to be higher in males than in females.Our findings suggest that PCR, RDT and microscopy can potentially determine hotspots at moderate transmission intensities, but PCR testing has a diagnostic advantage as transmission intensity falls. Therefore, malaria control programs should consider PCR testing when the prevalence of infection is low." @default.
- W2921402778 created "2019-03-22" @default.
- W2921402778 creator A5017136816 @default.
- W2921402778 creator A5052455152 @default.
- W2921402778 creator A5066051373 @default.
- W2921402778 creator A5070177147 @default.
- W2921402778 date "2018-10-01" @default.
- W2921402778 modified "2023-09-27" @default.
- W2921402778 title "High-Sensitivity Detection of Human Malaria Parasites by the Use of Rapid Diagnostic Tests and Nested Polymerase Chain Reaction in Burdened Communities of North East India" @default.
- W2921402778 cites W1965537883 @default.
- W2921402778 cites W1966474428 @default.
- W2921402778 cites W1977784023 @default.
- W2921402778 cites W1990497262 @default.
- W2921402778 cites W2010328983 @default.
- W2921402778 cites W2072273656 @default.
- W2921402778 cites W2073519713 @default.
- W2921402778 cites W2079263157 @default.
- W2921402778 cites W2112225093 @default.
- W2921402778 cites W2115837962 @default.
- W2921402778 cites W2117528530 @default.
- W2921402778 cites W2121049991 @default.
- W2921402778 cites W2131478872 @default.
- W2921402778 cites W2143212783 @default.
- W2921402778 cites W2144029515 @default.
- W2921402778 cites W2166805205 @default.
- W2921402778 cites W2166806965 @default.
- W2921402778 cites W2169986867 @default.
- W2921402778 cites W2330751868 @default.
- W2921402778 cites W2399484661 @default.
- W2921402778 cites W4241609512 @default.
- W2921402778 doi "https://doi.org/10.4103/ijmm.ijmm_18_394" @default.
- W2921402778 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30880704" @default.
- W2921402778 hasPublicationYear "2018" @default.
- W2921402778 type Work @default.
- W2921402778 sameAs 2921402778 @default.
- W2921402778 citedByCount "1" @default.
- W2921402778 countsByYear W29214027782020 @default.
- W2921402778 crossrefType "journal-article" @default.
- W2921402778 hasAuthorship W2921402778A5017136816 @default.
- W2921402778 hasAuthorship W2921402778A5052455152 @default.
- W2921402778 hasAuthorship W2921402778A5066051373 @default.
- W2921402778 hasAuthorship W2921402778A5070177147 @default.
- W2921402778 hasBestOaLocation W29214027781 @default.
- W2921402778 hasConcept C104317684 @default.
- W2921402778 hasConcept C107130276 @default.
- W2921402778 hasConcept C126322002 @default.
- W2921402778 hasConcept C157431215 @default.
- W2921402778 hasConcept C203014093 @default.
- W2921402778 hasConcept C2778048844 @default.
- W2921402778 hasConcept C2778371730 @default.
- W2921402778 hasConcept C2780261877 @default.
- W2921402778 hasConcept C42972112 @default.
- W2921402778 hasConcept C49105822 @default.
- W2921402778 hasConcept C54355233 @default.
- W2921402778 hasConcept C71924100 @default.
- W2921402778 hasConcept C86803240 @default.
- W2921402778 hasConceptScore W2921402778C104317684 @default.
- W2921402778 hasConceptScore W2921402778C107130276 @default.
- W2921402778 hasConceptScore W2921402778C126322002 @default.
- W2921402778 hasConceptScore W2921402778C157431215 @default.
- W2921402778 hasConceptScore W2921402778C203014093 @default.
- W2921402778 hasConceptScore W2921402778C2778048844 @default.
- W2921402778 hasConceptScore W2921402778C2778371730 @default.
- W2921402778 hasConceptScore W2921402778C2780261877 @default.
- W2921402778 hasConceptScore W2921402778C42972112 @default.
- W2921402778 hasConceptScore W2921402778C49105822 @default.
- W2921402778 hasConceptScore W2921402778C54355233 @default.
- W2921402778 hasConceptScore W2921402778C71924100 @default.
- W2921402778 hasConceptScore W2921402778C86803240 @default.
- W2921402778 hasLocation W29214027781 @default.
- W2921402778 hasLocation W29214027782 @default.
- W2921402778 hasOpenAccess W2921402778 @default.
- W2921402778 hasPrimaryLocation W29214027781 @default.
- W2921402778 hasRelatedWork W2022460484 @default.
- W2921402778 hasRelatedWork W2111533837 @default.
- W2921402778 hasRelatedWork W2112217960 @default.
- W2921402778 hasRelatedWork W2112342754 @default.
- W2921402778 hasRelatedWork W2126740217 @default.
- W2921402778 hasRelatedWork W2223307961 @default.
- W2921402778 hasRelatedWork W2921402778 @default.
- W2921402778 hasRelatedWork W2963186091 @default.
- W2921402778 hasRelatedWork W3133188342 @default.
- W2921402778 hasRelatedWork W4283067428 @default.
- W2921402778 isParatext "false" @default.
- W2921402778 isRetracted "false" @default.
- W2921402778 magId "2921402778" @default.
- W2921402778 workType "article" @default.